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Postnatal development in cynomolgus monkeys following prenatal exposure to natalizumab, an alpha4 integrin inhibitor.
Wehner NG, Shopp G, Osterburg I, Fuchs A, Buse E, Clarke J. Wehner NG, et al. Among authors: shopp g. Birth Defects Res B Dev Reprod Toxicol. 2009 Apr;86(2):144-56. doi: 10.1002/bdrb.20193. Birth Defects Res B Dev Reprod Toxicol. 2009. PMID: 19283860
METHODS: The effects of prenatal exposure to natalizumab on postnatal development were assessed in cynomolgus monkeys at doses of 0 and 30 mg/kg administered intravenously every other day from gestational day (GD) 20 to 70 or GD 20 to term. Infants were delivered by natura …
METHODS: The effects of prenatal exposure to natalizumab on postnatal development were assessed in cynomolgus monkeys at doses of 0 and 30 m …