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Use of Mitomycin-C in Laryngotracheal Stenosis: A Focused Clinical Review.
Di Felice C, Machuzak MS, Shepherd RW. Di Felice C, et al. Among authors: shepherd rw. J Bronchology Interv Pulmonol. 2023 Jul 1;30(3):223-231. doi: 10.1097/LBR.0000000000000933. J Bronchology Interv Pulmonol. 2023. PMID: 37271867 Review.
Single versus multiple application(s) of MMC resulted in similar restenosis rates at long-term follow-up. Complications related to MMC use are rarely reported using conventional doses (0.4 mg/mL). ...
Single versus multiple application(s) of MMC resulted in similar restenosis rates at long-term follow-up. Complications related to MM …
Neonatal BCG vaccination is associated with a long-term DNA methylation signature in circulating monocytes.
Bannister S, Kim B, Domínguez-Andrés J, Kilic G, Ansell BRE, Neeland MR, Moorlag SJCFM, Matzaraki V, Vlahos A, Shepherd R, Germano S, Bahlo M, Messina NL, Saffery R, Netea MG, Curtis N, Novakovic B. Bannister S, et al. Among authors: shepherd r. Sci Adv. 2022 Aug 5;8(31):eabn4002. doi: 10.1126/sciadv.abn4002. Epub 2022 Aug 5. Sci Adv. 2022. PMID: 35930640 Free PMC article.
Methadone-related death in detention.
Flanagan RJ, Shepherd RT. Flanagan RJ, et al. Among authors: shepherd rt. J Forensic Leg Med. 2022 May;88:102356. doi: 10.1016/j.jflm.2022.102356. Epub 2022 Apr 26. J Forensic Leg Med. 2022. PMID: 35500444

Those who died within 7 days of the commencement of methadone treatment were significantly younger (Mann-Whitney U 102.5, p < 0.05), were prescribed a significantly lower dose (U = 80.0, p < 0.05) and had significantly lower blood methadone concentrations at death (U = 106.

…

Those who died within 7 days of the commencement of methadone treatment were significantly younger (Mann-Whitney U 102.5, p < 0.05), were

…
Acceptability and feasibility of an online physical activity program for women over 50: a pilot trial.
Wallbank G, Sherrington C, Hassett L, Kwasnicka D, Chau JY, Phongsavan P, Grunseit A, Martin F, Canning CG, Baird M, Shepherd R, Tiedemann A. Wallbank G, et al. Among authors: shepherd r. Transl Behav Med. 2022 Feb 16;12(2):225-236. doi: 10.1093/tbm/ibab161. Transl Behav Med. 2022. PMID: 35020938 Clinical Trial.
The [Active Women over 50 Online] program demonstrated acceptability and feasibility among the target population, and effectiveness in some domains in the short term. Results warrant further testing in a full-scale RCT. Regular physical activity benefits health at all ages …
The [Active Women over 50 Online] program demonstrated acceptability and feasibility among the target population, and effectiveness in some …
Platinum dissolution and tissue response following long-term electrical stimulation at high charge densities.
Shepherd RK, Carter PM, Dalrymple AN, Enke YL, Wise AK, Nguyen T, Firth J, Thompson A, Fallon JB. Shepherd RK, et al. J Neural Eng. 2021 Mar 17;18(3):10.1088/1741-2552/abe5ba. doi: 10.1088/1741-2552/abe5ba. J Neural Eng. 2021. PMID: 33578409 Free PMC article.
Recent studies have reported particulate platinum (Pt) associated with long-term clinical use of these devices, highlighting the need for more carefully defined safety limits. ...Finally, increased charge storage capacity and charge injection limit reflected the more exten …
Recent studies have reported particulate platinum (Pt) associated with long-term clinical use of these devices, highlighting the need …
Chronic intracochlear electrical stimulation at high charge densities: reducing platinum dissolution.
Shepherd RK, Carter PM, Enke YL, Thompson A, Flynn B, Trang EP, Dalrymple AN, Fallon JB. Shepherd RK, et al. J Neural Eng. 2020 Oct 8;17(5):056009. doi: 10.1088/1741-2552/abb7a6. J Neural Eng. 2020. PMID: 32916669 Free PMC article.
OBJECTIVE: Cochleae of long-term cochlear implant users have shown evidence of particulate platinum (Pt) corroded from the surface of Pt electrodes. ...
OBJECTIVE: Cochleae of long-term cochlear implant users have shown evidence of particulate platinum (Pt) corroded from the surface of …
New molecular therapies for the treatment of hearing loss.
Ma Y, Wise AK, Shepherd RK, Richardson RT. Ma Y, et al. Among authors: shepherd rk. Pharmacol Ther. 2019 Aug;200:190-209. doi: 10.1016/j.pharmthera.2019.05.003. Epub 2019 May 8. Pharmacol Ther. 2019. PMID: 31075354 Free PMC article. Review.
Drug therapy delivery technologies are being employed to address the specific needs of neurotrophin and other therapies for hearing loss that include the need for high doses, long-term delivery, localised or cell-specific targeting and techniques for their safe and efficac …
Drug therapy delivery technologies are being employed to address the specific needs of neurotrophin and other therapies for hearing loss tha …
Chronic intracochlear electrical stimulation at high charge densities results in platinum dissolution but not neural loss or functional changes in vivo.
Shepherd RK, Carter PM, Enke YL, Wise AK, Fallon JB. Shepherd RK, et al. J Neural Eng. 2019 Apr;16(2):026009. doi: 10.1088/1741-2552/aaf66b. Epub 2018 Dec 5. J Neural Eng. 2019. PMID: 30523828 Free PMC article.
More recently, histological examination of cochleae from patients that were long-term cochlear implant users have shown evidence of particulate platinum (Pt). ...
More recently, histological examination of cochleae from patients that were long-term cochlear implant users have shown evidence of p …
Gel-Mediated Electrospray Assembly of Silica Supraparticles for Sustained Drug Delivery.
Ma Y, Björnmalm M, Wise AK, Cortez-Jugo C, Revalor E, Ju Y, Feeney OM, Richardson RT, Hanssen E, Shepherd RK, Porter CJH, Caruso F. Ma Y, et al. Among authors: shepherd rk. ACS Appl Mater Interfaces. 2018 Sep 19;10(37):31019-31031. doi: 10.1021/acsami.8b10415. Epub 2018 Sep 7. ACS Appl Mater Interfaces. 2018. PMID: 30192499 Free article.
Supraparticles (SPs) composed of smaller colloidal particles provide a platform for the long-term, controlled release of therapeutics in biomedical applications. ...Drug loading kinetics and loading capacity for six different types of Si-SPs, using a model protein drug (fl …
Supraparticles (SPs) composed of smaller colloidal particles provide a platform for the long-term, controlled release of therapeutics …
Early, Accurate Diagnosis and Early Intervention in Cerebral Palsy: Advances in Diagnosis and Treatment.
Novak I, Morgan C, Adde L, Blackman J, Boyd RN, Brunstrom-Hernandez J, Cioni G, Damiano D, Darrah J, Eliasson AC, de Vries LS, Einspieler C, Fahey M, Fehlings D, Ferriero DM, Fetters L, Fiori S, Forssberg H, Gordon AM, Greaves S, Guzzetta A, Hadders-Algra M, Harbourne R, Kakooza-Mwesige A, Karlsson P, Krumlinde-Sundholm L, Latal B, Loughran-Fowlds A, Maitre N, McIntyre S, Noritz G, Pennington L, Romeo DM, Shepherd R, Spittle AJ, Thornton M, Valentine J, Walker K, White R, Badawi N. Novak I, et al. Among authors: shepherd r. JAMA Pediatr. 2017 Sep 1;171(9):897-907. doi: 10.1001/jamapediatrics.2017.1689. JAMA Pediatr. 2017. PMID: 28715518 Free PMC article. Review.
Before 5 months' corrected age, the most predictive tools for detecting risk are term-age magnetic resonance imaging (86%-89% sensitivity), the Prechtl Qualitative Assessment of General Movements (98% sensitivity), and the Hammersmith Infant Neurological Examination (90% s …
Before 5 months' corrected age, the most predictive tools for detecting risk are term-age magnetic resonance imaging (86%-89% sensiti …
71 results