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X-linked myotubular myopathy associated with an MTM1 variant in a Maine coon cat.
Kopke MA, Shelton GD, Lyons LA, Wall MJ, Pemberton S, Gedye KR, Owen R, Guo LT, Buckley RM, Valencia JA; 99 Lives Consortium; Jones BR. Kopke MA, et al. Among authors: shelton gd. J Vet Intern Med. 2022 Sep;36(5):1800-1805. doi: 10.1111/jvim.16509. Epub 2022 Aug 13. J Vet Intern Med. 2022. PMID: 35962713 Free PMC article.
Genetic testing for spinal muscular atrophy (LIX1) was negative. Given the progressive nature and suspected poor long-term prognosis, the owners elected euthanasia. Histopathology of skeletal muscle obtained post-mortem disclosed numerous rounded atrophic or hypotrophic fi …
Genetic testing for spinal muscular atrophy (LIX1) was negative. Given the progressive nature and suspected poor long-term prognosis, …
Glossitis in an older non-corgi dog: Diagnosis and long-term follow-up.
Krenzke LR, Cameron S, Pritchard JC, Webb DB, Guo LT, Shelton GD. Krenzke LR, et al. Among authors: shelton gd. Can Vet J. 2022 Aug;63(8):825-829. Can Vet J. 2022. PMID: 35919473 Free PMC article.
The dog was treated with a tapering course of prednisone over 2 months and cyclosporine long-term. The dog was maintained on cyclosporine alone for > 2 years and clinical signs remained static, although multiple episodes of aspiration pneumonia occurred. ...
The dog was treated with a tapering course of prednisone over 2 months and cyclosporine long-term. The dog was maintained on cyclospo …
Clinical features and outcome of acquired myasthenia gravis in 94 dogs.
Forgash JT, Chang YM, Mittelman NS, Petesch S, Benedicenti L, Galban E, Hammond JJ, Glass EN, Barker JR, Shelton GD, Luo J, Garden OA. Forgash JT, et al. Among authors: shelton gd. J Vet Intern Med. 2021 Sep;35(5):2315-2326. doi: 10.1111/jvim.16223. Epub 2021 Jul 31. J Vet Intern Med. 2021. PMID: 34331481 Free PMC article.
HYPOTHESIS/OBJECTIVES: Of dogs with MG, advancing age and comorbid neoplasia are associated with poor long-term prognosis and low rates of remission. ANIMALS: Ninety-four client-owned dogs with MG diagnosed by acetylcholine receptor antibody (AChR Ab) assay between 2001 an …
HYPOTHESIS/OBJECTIVES: Of dogs with MG, advancing age and comorbid neoplasia are associated with poor long-term prognosis and low rat …
Clinical characteristics of non-infectious inflammatory myopathy in the boxer dog.
Hong HP, Thomovsky SA, Lewis MJ, Bentley RT, Shelton GD. Hong HP, et al. Among authors: shelton gd. J Small Anim Pract. 2021 Sep;62(9):765-774. doi: 10.1111/jsap.13350. Epub 2021 May 17. J Small Anim Pract. 2021. PMID: 34002872
CLINICAL SIGNIFICANCE: Boxer dogs with non-infectious inflammatory myopathy can present for generalised weakness and dysphagia; long-term successful outcome is uncommon. The relationship between neoplasia and non-infectious inflammatory myopathy in boxer dogs remains uncle …
CLINICAL SIGNIFICANCE: Boxer dogs with non-infectious inflammatory myopathy can present for generalised weakness and dysphagia; long-term …
Long-term outcome of Miniature Schnauzers with genetically confirmed demyelinating polyneuropathy: 12 cases.
Farré Mariné A, Granger N, Bertolani C, Mascort Boixeda J, Shelton GD, Luján Feliu-Pascual A. Farré Mariné A, et al. Among authors: shelton gd. J Vet Intern Med. 2020 Sep;34(5):2005-2011. doi: 10.1111/jvim.15861. Epub 2020 Aug 1. J Vet Intern Med. 2020. PMID: 32738000 Free PMC article.
A genetic variant of MTRM13/SBF2 has been identified as causative in affected Miniature Schnauzers with this polyneuropathy. OBJECTIVE: To provide data on the long-term progression in affected Miniature Schnauzers from Spain confirmed with the MTRM13/SBF2 genetic variant. …
A genetic variant of MTRM13/SBF2 has been identified as causative in affected Miniature Schnauzers with this polyneuropathy. OBJECTIVE: To p …
Risk Factors and Outcomes in Cats with Acquired Myasthenia Gravis (2001-2012).
Hague DW, Humphries HD, Mitchell MA, Shelton GD. Hague DW, et al. Among authors: shelton gd. J Vet Intern Med. 2015 Sep-Oct;29(5):1307-12. doi: 10.1111/jvim.13596. Epub 2015 Aug 26. J Vet Intern Med. 2015. PMID: 26308738 Free PMC article.
ANIMALS: Two hundred and thirty-five cats with MG. METHODS: Retrospective case study to evaluate the long-term outcome and incidence of spontaneous remission in myasthenic cats. ...Spontaneous remission is not common and clinicians should warn owners of the necessity for l …
ANIMALS: Two hundred and thirty-five cats with MG. METHODS: Retrospective case study to evaluate the long-term outcome and incidence …
Resolution of polyneuropathy in a hypothyroid dog following thyroid supplementation.
Utsugi S, Saito M, Shelton GD. Utsugi S, et al. Among authors: shelton gd. J Am Anim Hosp Assoc. 2014 Sep-Oct;50(5):345-9. doi: 10.5326/JAAHA-MS-6035. J Am Anim Hosp Assoc. 2014. PMID: 25028439
Although the occurrence of polyneuropathy in dogs resulting from hypothyroidism has been controversial, the study authors demonstrated that hypothyroid polyneuropathy can occur in dogs as documented in humans. This is the first report describing long-term follow-up informa …
Although the occurrence of polyneuropathy in dogs resulting from hypothyroidism has been controversial, the study authors demonstrated that …
Recurrent demyelination and remyelination in 37 young Bengal cats with polyneuropathy.
Bensfield AC, Evans J, Pesayco JP, Mizisin AP, Shelton GD. Bensfield AC, et al. Among authors: shelton gd. J Vet Intern Med. 2011 Jul-Aug;25(4):882-9. doi: 10.1111/j.1939-1676.2011.0740.x. Epub 2011 Jun 20. J Vet Intern Med. 2011. PMID: 21689154 Free article.
Pathological changes were characterized at the light and electron microscopic level and by morphometry. Clinical information and long-term outcome from case records of Bengal cats with histologically confirmed peripheral neuropathy were then assessed. ...
Pathological changes were characterized at the light and electron microscopic level and by morphometry. Clinical information and long-ter …
Myasthenia gravis in dogs with an emphasis on treatment and critical care management.
Khorzad R, Whelan M, Sisson A, Shelton GD. Khorzad R, et al. Among authors: shelton gd. J Vet Emerg Crit Care (San Antonio). 2011 Jun;21(3):193-208. doi: 10.1111/j.1476-4431.2011.00636.x. Epub 2011 May 10. J Vet Emerg Crit Care (San Antonio). 2011. PMID: 21631705 Review.
Recent studies, mainly case series and case reports, emphasize the use of immunomodulatory treatments as an alternative for long-term treatment. However, there are no randomized, controlled studies on treatment with immunomodulatory therapy for MG in dogs available to asse …
Recent studies, mainly case series and case reports, emphasize the use of immunomodulatory treatments as an alternative for long-term …
Histopathological confirmation of polyneuropathy in 11 dogs with laryngeal paralysis.
Thieman KM, Krahwinkel DJ, Sims MH, Shelton GD. Thieman KM, et al. Among authors: shelton gd. J Am Anim Hosp Assoc. 2010 May-Jun;46(3):161-7. doi: 10.5326/0460161. J Am Anim Hosp Assoc. 2010. PMID: 20439938
Establishing a diagnosis of a more involved disease process is relevant for long-term prognosis....
Establishing a diagnosis of a more involved disease process is relevant for long-term prognosis....
12 results