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Page 1
Prevalence and Predictors of Functional Vitamin K Insufficiency in Mothers and Newborns in Uganda.
Santorino D, Siedner MJ, Mwanga-Amumpaire J, Shearer MJ, Harrington DJ, Wariyar U. Santorino D, et al. Among authors: shearer mj. Nutrients. 2015 Oct 16;7(10):8545-52. doi: 10.3390/nu7105408. Nutrients. 2015. PMID: 26501317 Free PMC article.
We found no significant predictors of newborn VK insufficiency, including infant weight (AOR (adjusted odds ratio) 1.85, 95% CI (confidence interval) 0.15-22.49), gender (AOR 0.54, 95% CI 0.26-1.11), term birth (AOR 0.72, 95% CI 0.20-2.62), maternal VK-rich diet (AO …
We found no significant predictors of newborn VK insufficiency, including infant weight (AOR (adjusted odds ratio) 1.85, 95% CI (confidence …
Efficient photoelectrochemical hydrogen generation using heterostructures of Si and chemically exfoliated metallic MoS2.
Ding Q, Meng F, English CR, Cabán-Acevedo M, Shearer MJ, Liang D, Daniel AS, Hamers RJ, Jin S. Ding Q, et al. Among authors: shearer mj. J Am Chem Soc. 2014 Jun 18;136(24):8504-7. doi: 10.1021/ja5025673. Epub 2014 Jun 3. J Am Chem Soc. 2014. PMID: 24892384
Photocurrents up to 17.6 mA/cm(2) at 0 V vs reversible hydrogen electrode were achieved under simulated 1 sun irradiation, and excellent stability was demonstrated over long-term operation. Electrochemical impedance spectroscopy revealed low charge-transfer resistances at …
Photocurrents up to 17.6 mA/cm(2) at 0 V vs reversible hydrogen electrode were achieved under simulated 1 sun irradiation, and excellent sta …
Association of vitamin K status with adiponectin and body composition in healthy subjects: uncarboxylated osteocalcin is not associated with fat mass and body weight.
Knapen MH, Schurgers LJ, Shearer MJ, Newman P, Theuwissen E, Vermeer C. Knapen MH, et al. Among authors: shearer mj. Br J Nutr. 2012 Sep 28;108(6):1017-24. doi: 10.1017/S000711451100626X. Epub 2011 Dec 5. Br J Nutr. 2012. PMID: 22136751 Clinical Trial.
These findings demonstrate that a high vitamin K status of bone has no effect on circulating adiponectin in healthy people and long-term vitamin K supplementation does not increase weight in healthy postmenopausal women....
These findings demonstrate that a high vitamin K status of bone has no effect on circulating adiponectin in healthy people and long-term …
Urinary excretion of vitamin K metabolites in term and preterm infants: relationship to vitamin K status and prophylaxis.
Harrington DJ, Clarke P, Card DJ, Mitchell SJ, Shearer MJ. Harrington DJ, et al. Among authors: shearer mj. Pediatr Res. 2010 Dec;68(6):508-12. doi: 10.1203/PDR.0b013e3181f981c7. Pediatr Res. 2010. PMID: 20814348
We measured the excretion of two urinary metabolites ( 24 h) of vitamin K (5C- and 7C-aglycones) in term infants before (n = 11) and after (n = 5) a 1000 mug i.m. dose of vitamin K1 (K1) and in preterm infants after 200 mug i.m. ...All term and 10 of 13 preterm infa …
We measured the excretion of two urinary metabolites ( 24 h) of vitamin K (5C- and 7C-aglycones) in term infants before (n = 11) and …
Two-year randomized controlled trial of vitamin K1 (phylloquinone) and vitamin D3 plus calcium on the bone health of older women.
Bolton-Smith C, McMurdo ME, Paterson CR, Mole PA, Harvey JM, Fenton ST, Prynne CJ, Mishra GD, Shearer MJ. Bolton-Smith C, et al. Among authors: shearer mj. J Bone Miner Res. 2007 Apr;22(4):509-19. doi: 10.1359/jbmr.070116. J Bone Miner Res. 2007. PMID: 17243866 Free article. Clinical Trial.
The substantial increase in gamma-carboxylation of osteocalcin by vitamin K may have long-term benefits and is potentially achievable by increased dietary intakes of vitamin K rather than by supplementation....
The substantial increase in gamma-carboxylation of osteocalcin by vitamin K may have long-term benefits and is potentially achievable …
Effect of calcium fortified milk supplementation with or without vitamin K on biochemical markers of bone turnover in premenopausal women.
Kruger MC, Booth CL, Coad J, Schollum LM, Kuhn-Sherlock B, Shearer MJ. Kruger MC, et al. Among authors: shearer mj. Nutrition. 2006 Nov-Dec;22(11-12):1120-8. doi: 10.1016/j.nut.2006.08.008. Epub 2006 Oct 9. Nutrition. 2006. PMID: 17030114 Clinical Trial.
Phylloquinone fortification substantially improved vitamin K status but had no demonstrable additive effect on bone turnover in this short-term study....
Phylloquinone fortification substantially improved vitamin K status but had no demonstrable additive effect on bone turnover in this short- …
Determination of phylloquinone (vitamin K1) in plasma and serum by HPLC with fluorescence detection.
Wang LY, Bates CJ, Yan L, Harrington DJ, Shearer MJ, Prentice A. Wang LY, et al. Among authors: shearer mj. Clin Chim Acta. 2004 Sep;347(1-2):199-207. doi: 10.1016/j.cccn.2004.04.030. Clin Chim Acta. 2004. PMID: 15313159
It is therefore adequately sensitive for 0.25 ml or less of plasma sample. Long-term reproducibility of quality assurance (QA) samples was verified over a period of 4 months. ...
It is therefore adequately sensitive for 0.25 ml or less of plasma sample. Long-term reproducibility of quality assurance (QA) sample …
Effect of vitamin K intake on the stability of oral anticoagulant treatment: dose-response relationships in healthy subjects.
Schurgers LJ, Shearer MJ, Hamulyák K, Stöcklin E, Vermeer C. Schurgers LJ, et al. Among authors: shearer mj. Blood. 2004 Nov 1;104(9):2682-9. doi: 10.1182/blood-2004-04-1525. Epub 2004 Jul 1. Blood. 2004. PMID: 15231565 Free article. Clinical Trial.
The short-lived response after meals of spinach and broccoli suggested an inefficient bioavailability from these 2 sources. We conclude that short-term variability in intake of K(1) is less important to fluctuations in the international normalized ratio (INR) than has been …
The short-lived response after meals of spinach and broccoli suggested an inefficient bioavailability from these 2 sources. We conclude that …
The uptake of lipoprotein-borne phylloquinone (vitamin K1) by osteoblasts and osteoblast-like cells: role of heparan sulfate proteoglycans and apolipoprotein E.
Newman P, Bonello F, Wierzbicki AS, Lumb P, Savidge GF, Shearer MJ. Newman P, et al. Among authors: shearer mj. J Bone Miner Res. 2002 Mar;17(3):426-33. doi: 10.1359/jbmr.2002.17.3.426. J Bone Miner Res. 2002. PMID: 11874234 Free article.
We also investigated the effect of heparin in this model since long-term heparin treatment causes osteopenia and the anticoagulant is known to impair normal lipoprotein metabolism. ...
We also investigated the effect of heparin in this model since long-term heparin treatment causes osteopenia and the anticoagulant is …
Vitamin K1 concentration in breast-fed neonates after oral or intramuscular administration of a single dose of a new mixed-micellar preparation of phylloquinone.
Schubiger G, Tönz O, Grüter J, Shearer MJ. Schubiger G, et al. Among authors: shearer mj. J Pediatr Gastroenterol Nutr. 1993 May;16(4):435-9. doi: 10.1097/00005176-199305000-00016. J Pediatr Gastroenterol Nutr. 1993. PMID: 8315554 Clinical Trial.
The narrow range of plasma concentrations at 24 h and 4 days suggests a greater consistency of absorption from this micellar preparation than from other emulsion-based preparations. Further studies are required to assess the long-term protection of a single oral dose again …
The narrow range of plasma concentrations at 24 h and 4 days suggests a greater consistency of absorption from this micellar preparation tha …
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