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The Association of Early Corticosteroid Therapy With Clinical and Health-Related Quality of Life Outcomes in Children With Septic Shock.
Kamps NN, Banks R, Reeder RW, Berg RA, Newth CJ, Pollack MM, Meert KL, Carcillo JA, Mourani PM, Sorenson S, Varni JW, Cengiz P, Zimmerman JJ; Life After Pediatric Sepsis Evaluation (LAPSE) Investigators. Kamps NN, et al. Pediatr Crit Care Med. 2022 Sep 1;23(9):687-697. doi: 10.1097/PCC.0000000000003009. Epub 2022 Jun 10. Pediatr Crit Care Med. 2022. PMID: 35695852 Free PMC article.
After weighting corticosteroid therapy administration propensity across potentially confounding baseline characteristics, differences in outcomes associated with treatment were not statistically significant (adjusted effect or odds ratio [95% CI]): vasoactive-inotropic support du …
After weighting corticosteroid therapy administration propensity across potentially confounding baseline characteristics, differences in out …
"I Didn't Want My Baby to Pass, But I Didn't Want Him Suffering Either": Comparing Bereaved Parents' Narratives With Nursing End-of-Life Assessments in the Pediatric Intensive Care Unit.
Broden EG, Hinds PS, Werner-Lin AV, Curley MAQ; for the RESTORE Study Investigators. Broden EG, et al. J Hosp Palliat Nurs. 2022 Oct 1;24(5):271-280. doi: 10.1097/NJH.0000000000000884. Epub 2022 Jun 6. J Hosp Palliat Nurs. 2022. PMID: 35666188 Free PMC article.
Little is known about how nursing care at the end of a child's life impacts long-term parental bereavement. We aimed to explain, contextualize, and examine comparisons between quantitative trends in children's end-of-life care and parents' qualitative perceptions. ...
Little is known about how nursing care at the end of a child's life impacts long-term parental bereavement. We aimed to explain, cont …
Miniaturized wireless, skin-integrated sensor networks for quantifying full-body movement behaviors and vital signs in infants.
Jeong H, Kwak SS, Sohn S, Lee JY, Lee YJ, O'Brien MK, Park Y, Avila R, Kim JT, Yoo JY, Irie M, Jang H, Ouyang W, Shawen N, Kang YJ, Kim SS, Tzavelis A, Lee K, Andersen RA, Huang Y, Jayaraman A, Davis MM, Shanley T, Wakschlag LS, Krogh-Jespersen S, Xu S, Ryan SW, Lieber RL, Rogers JA. Jeong H, et al. Among authors: shanley t. Proc Natl Acad Sci U S A. 2021 Oct 26;118(43):e2104925118. doi: 10.1073/pnas.2104925118. Proc Natl Acad Sci U S A. 2021. PMID: 34663725 Free PMC article.
Clinical implementations with infants at low and at elevated risks for atypical neuromotor development illustrates application of this system in quantitative and semiquantitative assessments of patterns of gross motor skills, along with body temperature, heart rate, and respirato …
Clinical implementations with infants at low and at elevated risks for atypical neuromotor development illustrates application of this syste …
Trajectory of Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock.
Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW; Life After Pediatric Sepsis Evaluation (LAPSE) Investigators. Zimmerman JJ, et al. Crit Care Med. 2020 Mar;48(3):329-337. doi: 10.1097/CCM.0000000000004123. Crit Care Med. 2020. PMID: 32058370 Free PMC article.
OBJECTIVES: In-hospital pediatric sepsis mortality has decreased substantially, but long-term mortality and morbidity among children initially surviving sepsis, is unknown. ...CONCLUSIONS: This investigation provides the first longitudinal description of long-term m …
OBJECTIVES: In-hospital pediatric sepsis mortality has decreased substantially, but long-term mortality and morbidity among children …
Critical Illness Factors Associated With Long-Term Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock.
Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW; Life After Pediatric Sepsis Evaluation (LAPSE) Investigators. Zimmerman JJ, et al. Crit Care Med. 2020 Mar;48(3):319-328. doi: 10.1097/CCM.0000000000004122. Crit Care Med. 2020. PMID: 32058369 Free PMC article.
OBJECTIVES: A companion article reports the trajectory of long-term mortality and significant health-related quality of life disability among children encountering septic shock. ...
OBJECTIVES: A companion article reports the trajectory of long-term mortality and significant health-related quality of life disabili …
Platelet Transfusion Practice and Related Outcomes in Pediatric Extracorporeal Membrane Oxygenation.
Cashen K, Dalton H, Reeder RW, Saini A, Zuppa AF, Shanley TP, Newth CJL, Pollack MM, Wessel D, Carcillo J, Harrison R, Dean JM, Meert KL; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN). Cashen K, et al. Among authors: shanley tp. Pediatr Crit Care Med. 2020 Feb;21(2):178-185. doi: 10.1097/PCC.0000000000002102. Pediatr Crit Care Med. 2020. PMID: 31568245 Free PMC article.
Variables independently associated with decreased daily thrombotic risk included full-term neonatal age and an acute diagnosis of airway abnormality. CONCLUSIONS: Platelet transfusion was common in this multisite pediatric extracorporeal membrane oxygenation cohort. ...
Variables independently associated with decreased daily thrombotic risk included full-term neonatal age and an acute diagnosis of air …
Language Analysis as a Window to Bereaved Parents' Emotions During a Parent-Physician Bereavement Meeting.
Eggly S, Manning MA, Slatcher RB, Berg RA, Wessel DL, Newth CJ, Shanley TP, Harrison R, Dalton H, Dean JM, Doctor A, Jenkins T, Meert KL. Eggly S, et al. Among authors: shanley tp. J Lang Soc Psychol. 2015 Mar;34(2):181-199. doi: 10.1177/0261927X14555549. Epub 2014 Oct 30. J Lang Soc Psychol. 2015. PMID: 26726278 Free PMC article.
Parents' use of positive emotion words was negatively related to their own and/or their spouse's appraisals of the meeting, suggesting that parents who have a positive emotional experience during the meeting may also have a short-term negative reaction. Language analysis c …
Parents' use of positive emotion words was negatively related to their own and/or their spouse's appraisals of the meeting, suggesting that …
Time for a neonatal-specific consensus definition for sepsis.
Wynn JL, Wong HR, Shanley TP, Bizzarro MJ, Saiman L, Polin RA. Wynn JL, et al. Among authors: shanley tp. Pediatr Crit Care Med. 2014 Jul;15(6):523-8. doi: 10.1097/PCC.0000000000000157. Pediatr Crit Care Med. 2014. PMID: 24751791 Free PMC article. Review.
OBJECTIVE: To review the accuracy of the pediatric consensus definition of sepsis in term neonates and to determine the definition of neonatal sepsis used. ...Thus, specific consensus definitions for both term and preterm neonates are needed. Such definitions are cr …
OBJECTIVE: To review the accuracy of the pediatric consensus definition of sepsis in term neonates and to determine the definition of …
Inpatient health care utilization for children dependent on long-term mechanical ventilation.
Benneyworth BD, Gebremariam A, Clark SJ, Shanley TP, Davis MM. Benneyworth BD, et al. Among authors: shanley tp. Pediatrics. 2011 Jun;127(6):e1533-41. doi: 10.1542/peds.2010-2026. Epub 2011 May 16. Pediatrics. 2011. PMID: 21576303 Free PMC article.
OBJECTIVE: The objective was to describe the characteristics of pediatric discharges associated with long-term mechanical ventilation (LTMV) compared with those with complex chronic conditions (CCCs), and evaluate trends over time in health care utilization for the dischar …
OBJECTIVE: The objective was to describe the characteristics of pediatric discharges associated with long-term mechanical ventilation …
New concepts of IL-10-induced lung fibrosis: fibrocyte recruitment and M2 activation in a CCL2/CCR2 axis.
Sun L, Louie MC, Vannella KM, Wilke CA, LeVine AM, Moore BB, Shanley TP. Sun L, et al. Among authors: shanley tp. Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L341-53. doi: 10.1152/ajplung.00122.2010. Epub 2010 Dec 3. Am J Physiol Lung Cell Mol Physiol. 2011. PMID: 21131395 Free PMC article.
Few prior studies have linked IL-10 with the inhibition of fibrosis principally on the basis of regulating inflammation thought to be driving fibroproliferation. In contrast, in a model of long-term overexpression of IL-10, we observed marked induction of lung fibrosis in …
Few prior studies have linked IL-10 with the inhibition of fibrosis principally on the basis of regulating inflammation thought to be drivin …
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