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Association of Vitamin C, Thiamine, and Hydrocortisone Infusion With Long-term Cognitive, Psychological, and Functional Outcomes in Sepsis Survivors: A Secondary Analysis of the Vitamin C, Thiamine, and Steroids in Sepsis Randomized Clinical Trial.
Williams Roberson S, Nwosu S, Collar EM, Kiehl AL, Harrison FE, Bastarache J, Wilson JE, Mart MF, Sevransky JE, Ely EW, Lindsell CJ, Jackson JC; VICTAS Investigators. Williams Roberson S, et al. Among authors: sevransky je. JAMA Netw Open. 2023 Feb 1;6(2):e230380. doi: 10.1001/jamanetworkopen.2023.0380. JAMA Netw Open. 2023. PMID: 36853612 Free PMC article. Clinical Trial.
IMPORTANCE: Sepsis is associated with long-term cognitive impairment and worse psychological and functional outcomes. ...These findings challenge the hypothesis that antioxidant and anti-inflammatory therapy during critical illness mitigates the development of long-term …
IMPORTANCE: Sepsis is associated with long-term cognitive impairment and worse psychological and functional outcomes. ...These findin …
Physical complications in acute lung injury survivors: a two-year longitudinal prospective study.
Fan E, Dowdy DW, Colantuoni E, Mendez-Tellez PA, Sevransky JE, Shanholtz C, Himmelfarb CR, Desai SV, Ciesla N, Herridge MS, Pronovost PJ, Needham DM. Fan E, et al. Among authors: sevransky je. Crit Care Med. 2014 Apr;42(4):849-59. doi: 10.1097/CCM.0000000000000040. Crit Care Med. 2014. PMID: 24247473 Free PMC article.
Evidence-based methods to reduce the duration of bed rest during critical illness may be important for improving these long-term impairments....
Evidence-based methods to reduce the duration of bed rest during critical illness may be important for improving these long-term impa …
Lung protective mechanical ventilation and two year survival in patients with acute lung injury: prospective cohort study.
Needham DM, Colantuoni E, Mendez-Tellez PA, Dinglas VD, Sevransky JE, Dennison Himmelfarb CR, Desai SV, Shanholtz C, Brower RG, Pronovost PJ. Needham DM, et al. Among authors: sevransky je. BMJ. 2012 Apr 5;344:e2124. doi: 10.1136/bmj.e2124. BMJ. 2012. PMID: 22491953 Free PMC article.
CONCLUSIONS: Lung protective mechanical ventilation was associated with a substantial long term survival benefit for patients with acute lung injury. Greater use of lung protective ventilation in routine clinical practice could reduce long term mortality in patients …
CONCLUSIONS: Lung protective mechanical ventilation was associated with a substantial long term survival benefit for patients with ac …
Short-term mortality prediction for acute lung injury patients: external validation of the Acute Respiratory Distress Syndrome Network prediction model.
Damluji A, Colantuoni E, Mendez-Tellez PA, Sevransky JE, Fan E, Shanholtz C, Wojnar M, Pronovost PJ, Needham DM. Damluji A, et al. Among authors: sevransky je. Crit Care Med. 2011 May;39(5):1023-8. doi: 10.1097/CCM.0b013e31820ead31. Crit Care Med. 2011. PMID: 21761595 Free PMC article.
OBJECTIVE: An independent cohort of patients with acute lung injury was used to evaluate the external validity of a simple prediction model for short-term mortality previously developed using data from Acute Respiratory Distress Syndrome Network (ARDSNet) trials. ...
OBJECTIVE: An independent cohort of patients with acute lung injury was used to evaluate the external validity of a simple prediction model …
Human immunodeficiency virus infection and hospital mortality in acute lung injury patients.
Mendez-Tellez PA, Damluji A, Ammerman D, Colantuoni E, Fan E, Sevransky JE, Shanholtz C, Gallant JE, Pronovost PJ, Needham DM. Mendez-Tellez PA, et al. Among authors: sevransky je. Crit Care Med. 2010 Jul;38(7):1530-5. doi: 10.1097/CCM.0b013e3181e2a44b. Crit Care Med. 2010. PMID: 20453644
CONCLUSIONS: In patients with acute lung injury, human immunodeficiency virus-positive patients had similar hospital mortality as human immunodeficiency virus-negative patients; hence, human immunodeficiency virus status should not influence estimates of short-term prognos …
CONCLUSIONS: In patients with acute lung injury, human immunodeficiency virus-positive patients had similar hospital mortality as human immu …
Long-term mortality and quality of life in sepsis: a systematic review.
Winters BD, Eberlein M, Leung J, Needham DM, Pronovost PJ, Sevransky JE. Winters BD, et al. Among authors: sevransky je. Crit Care Med. 2010 May;38(5):1276-83. doi: 10.1097/CCM.0b013e3181d8cc1d. Crit Care Med. 2010. PMID: 20308885 Review.
BACKGROUND: Long-term outcomes from sepsis are poorly understood, and sepsis in patients may have different long-term effects on mortality and quality of life. ...Whether patients with sepsis have similar long-term mortality and quality-of-life effects is unc …
BACKGROUND: Long-term outcomes from sepsis are poorly understood, and sepsis in patients may have different long-term effects …