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Do senescence markers correlate in vitro and in situ within individual human donors?
Waaijer MEC, Gunn DA, van Heemst D, Slagboom PE, Sedivy JM, Dirks RW, Tanke HJ, Westendorp RGJ, Maier AB. Waaijer MEC, et al. Among authors: sedivy jm. Aging (Albany NY). 2018 Feb 28;10(2):278-289. doi: 10.18632/aging.101389. Aging (Albany NY). 2018. PMID: 29500330 Free PMC article.
Furthermore, we tested correlations between in vitro markers with in situ p16INK4a positivity.From 100 donors (20-91 years), cultured dermal fibroblasts were assessed for reactive oxygen species (ROS), telomere-associated foci (TAF), p16INK4a and senescence-associated beta-gal (S …
Furthermore, we tested correlations between in vitro markers with in situ p16INK4a positivity.From 100 donors (20-91 years), cultured dermal …