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The Role of Long-Term Head-Down Bed Rest in Understanding Inter-Individual Variation in Response to the Spaceflight Environment: A Perspective Review.
Scott JPR, Kramer A, Petersen N, Green DA. Scott JPR, et al. Front Physiol. 2021 Feb 11;12:614619. doi: 10.3389/fphys.2021.614619. eCollection 2021. Front Physiol. 2021. PMID: 33643065 Free PMC article.
However, performance of countermeasure exercise renders it impossible to separate the effects of the spaceflight environment alone from those associated with exercise, whilst differences in exercise programs, spaceflight operations constraints, and environmental factors further c …
However, performance of countermeasure exercise renders it impossible to separate the effects of the spaceflight environment alone from thos …
Hydroxyurea Optimization through Precision Study (HOPS): study protocol for a randomized, multicenter trial in children with sickle cell anemia.
Meier ER, Creary SE, Heeney MM, Dong M, Appiah-Kubi AO, Nelson SC, Niss O, Piccone C, Quarmyne MO, Quinn CT, Saving KL, Scott JP, Talati R, Latham TS, Pfeiffer A, Shook LM, Vinks AA, Lane A, McGann PT. Meier ER, et al. Among authors: scott jp. Trials. 2020 Nov 27;21(1):983. doi: 10.1186/s13063-020-04912-z. Trials. 2020. PMID: 33246482 Free PMC article.
Hydroxyurea is the primary disease-modifying therapy for the SCD, with proven benefits to reduce both short-term and long-term complications. Despite the well-described inter-patient variability in pharmacokinetics (PK), pharmacodynamics, and optimal dose, hydroxyur …
Hydroxyurea is the primary disease-modifying therapy for the SCD, with proven benefits to reduce both short-term and long-term …
High-Intensity Interval Training: A Potential Exercise Countermeasure During Human Spaceflight.
Hurst C, Scott JPR, Weston KL, Weston M. Hurst C, et al. Among authors: scott jpr. Front Physiol. 2019 May 22;10:581. doi: 10.3389/fphys.2019.00581. eCollection 2019. Front Physiol. 2019. PMID: 31191330 Free PMC article. Review.
A considerable body of work has demonstrated substantial improvements in cardiorespiratory fitness following short-term training programmes, while emerging evidence suggests that HIT can positively impact aspects of neuromuscular fitness. ...
A considerable body of work has demonstrated substantial improvements in cardiorespiratory fitness following short-term training prog …
Clinical outcomes of splenectomy in children: report of the splenectomy in congenital hemolytic anemia registry.
Rice HE, Englum BR, Rothman J, Leonard S, Reiter A, Thornburg C, Brindle M, Wright N, Heeney MM, Smithers C, Brown RL, Kalfa T, Langer JC, Cada M, Oldham KT, Scott JP, St Peter S, Sharma M, Davidoff AM, Nottage K, Bernabe K, Wilson DB, Dutta S, Glader B, Crary SE, Dassinger MS, Dunbar L, Islam S, Kumar M, Rescorla F, Bruch S, Campbell A, Austin M, Sidonio R, Blakely ML; Splenectomy in Congenital Hemolytic Anemia (SICHA) Consortium. Rice HE, et al. Among authors: scott jp. Am J Hematol. 2015 Mar;90(3):187-92. doi: 10.1002/ajh.23888. Epub 2014 Nov 24. Am J Hematol. 2015. PMID: 25382665 Free PMC article.
We analyzed demographics and baseline clinical status, operative details, and outcomes at 4, 24, and 52 weeks after surgery. Results were summarized as hematologic outcomes, short-term adverse events (AEs) (30 days after surgery), and long-term AEs (31-365 days afte …
We analyzed demographics and baseline clinical status, operative details, and outcomes at 4, 24, and 52 weeks after surgery. Results were su …
Stroke With Transfusions Changing to Hydroxyurea (SWiTCH): a phase III randomized clinical trial for treatment of children with sickle cell anemia, stroke, and iron overload.
Ware RE, Schultz WH, Yovetich N, Mortier NA, Alvarez O, Hilliard L, Iyer RV, Miller ST, Rogers ZR, Scott JP, Waclawiw M, Helms RW. Ware RE, et al. Among authors: scott jp. Pediatr Blood Cancer. 2011 Dec 1;57(6):1011-7. doi: 10.1002/pbc.23145. Epub 2011 Aug 8. Pediatr Blood Cancer. 2011. PMID: 21826782 Free PMC article. Clinical Trial.
Chronic monthly erythrocyte transfusions effectively prevent recurrent stroke, but their long-term use is limited by serious side effects, including iron overload. ...
Chronic monthly erythrocyte transfusions effectively prevent recurrent stroke, but their long-term use is limited by serious side eff …
Outcome of lung transplantation in elderly recipients.
Tomaszek SC, Fibla JJ, Dierkhising RA, Scott JP, Shen KR, Wigle DA, Cassivi SD. Tomaszek SC, et al. Among authors: scott jp. Eur J Cardiothorac Surg. 2011 May;39(5):726-31. doi: 10.1016/j.ejcts.2010.08.034. Epub 2010 Nov 16. Eur J Cardiothorac Surg. 2011. PMID: 21084198
Lung transplantation in the elderly is controversial due to concerns over anticipated increased surgical risks, inferior long-term outcomes and proper stewardship in allocating limited donor organs. ...CONCLUSION: Increased age of 60 years and greater, in highly selected p …
Lung transplantation in the elderly is controversial due to concerns over anticipated increased surgical risks, inferior long-term ou …
Effect of myeloablative bone marrow transplantation on growth in children with sickle cell anaemia: results of the multicenter study of haematopoietic cell transplantation for sickle cell anaemia.
Eggleston B, Patience M, Edwards S, Adamkiewicz T, Buchanan GR, Davies SC, Dickerhoff R, Donfield S, Feig SA, Giller RH, Haight A, Horan J, Hsu LL, Kamani N, Lane P, Levine JE, Margolis D, Moore TB, Ohene-Frempong K, Redding-Lallinger R, Roberts IA, Rogers ZR, Sanders JE, Scott JP, Sleight B, Thompson AA, Sullivan KM, Walters MC; Multicenter Study of HCT for SCA. Eggleston B, et al. Among authors: scott jp. Br J Haematol. 2007 Feb;136(4):673-6. doi: 10.1111/j.1365-2141.2006.06486.x. Br J Haematol. 2007. PMID: 17223910 Free article. Clinical Trial.
Although haematopoietic cell transplantation (HCT) is curative for sickle cell anaemia (SCA), concerns about its short- and long-term toxicities limit its application. A potential toxicity is an adverse effect on growth. ...
Although haematopoietic cell transplantation (HCT) is curative for sickle cell anaemia (SCA), concerns about its short- and long-term …
Long-term hydroxyurea therapy for infants with sickle cell anemia: the HUSOFT extension study.
Hankins JS, Ware RE, Rogers ZR, Wynn LW, Lane PA, Scott JP, Wang WC. Hankins JS, et al. Among authors: scott jp. Blood. 2005 Oct 1;106(7):2269-75. doi: 10.1182/Blood-2004-12-4973. Blood. 2005. PMID: 16172253 Free PMC article. Clinical Trial.
The long-term efficacy and toxicity of hydroxyurea for infants are undefined, and its role in preventing organ dysfunction is unknown. Short-term feasibility of hydroxyurea administration, toxicities, hematologic effects, and effect on spleen function in infants wit …
The long-term efficacy and toxicity of hydroxyurea for infants are undefined, and its role in preventing organ dysfunction is unknown …
Outcome of patients with idiopathic pulmonary fibrosis admitted to the intensive care unit.
Saydain G, Islam A, Afessa B, Ryu JH, Scott JP, Peters SG. Saydain G, et al. Among authors: scott jp. Am J Respir Crit Care Med. 2002 Sep 15;166(6):839-42. doi: 10.1164/rccm.2104038. Am J Respir Crit Care Med. 2002. PMID: 12231494
These findings suggest that patients with IPF admitted to the ICU have poor short- and long-term prognosis. Patients with IPF and their families should be informed about the overall outlook when they make decisions about life support and ICU care....
These findings suggest that patients with IPF admitted to the ICU have poor short- and long-term prognosis. Patients with IPF and the …
28 results