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Page 1
Brain pathology and symptoms linked to concussion history: beyond chronic traumatic encephalopathy.
Taskina D, Zhu C, Schwab N, Hazrati LN. Taskina D, et al. Among authors: schwab n. Brain Commun. 2024 Feb 26;6(2):fcad314. doi: 10.1093/braincomms/fcad314. eCollection 2024. Brain Commun. 2024. PMID: 38560515
Repeated head trauma acquired through sports injuries has been associated with the development of long-term disabling symptoms that negatively impact the quality of life. ...
Repeated head trauma acquired through sports injuries has been associated with the development of long-term disabling symptoms that n …
Single-cell profiling reveals preferential reduction of memory B cell subsets in cladribine patients that correlates with treatment response.
Teschner VE, Fleck AK, Walter C, Schwarze AS, Eschborn M, Wirth T, Steinberg OV, Schulte-Mecklenbeck A, Lu IN, Herrera-Rivero M, Janoschka C, Lünemann JD, Schwab N, Meyer Zu Hörste G, Varghese J, Gross CC, Pul R, Kleinschnitz C, Mader S, Meinl E, Stoll M, Wiendl H, Klotz L. Teschner VE, et al. Among authors: schwab n. Ther Adv Neurol Disord. 2023 Dec 9;16:17562864231211077. doi: 10.1177/17562864231211077. eCollection 2023. Ther Adv Neurol Disord. 2023. PMID: 38084102 Free PMC article.
BACKGROUND: Cladribine is a highly effective immunotherapy that is applied in two short-term courses over 2 years and reduces relapse rate and disease progression in patients with relapsing multiple sclerosis (MS). Despite the short treatment period, cladribine has a long- …
BACKGROUND: Cladribine is a highly effective immunotherapy that is applied in two short-term courses over 2 years and reduces relapse …
Optimising prescribing in older adults with multimorbidity and polypharmacy in primary care (OPTICA): cluster randomised clinical trial.
Jungo KT, Ansorg AK, Floriani C, Rozsnyai Z, Schwab N, Meier R, Valeri F, Stalder O, Limacher A, Schneider C, Bagattini M, Trelle S, Spruit M, Schwenkglenks M, Rodondi N, Streit S. Jungo KT, et al. Among authors: schwab n. BMJ. 2023 May 24;381:e074054. doi: 10.1136/bmj-2022-074054. BMJ. 2023. PMID: 37225248 Free PMC article. Clinical Trial.
PARTICIPANTS: Eligible patients were 65 years of age with three or more chronic conditions and five or more long term medications. INTERVENTION: The intervention to optimise pharmacotherapy centred around an eCDSS was conducted by general practitioners, followed by shared …
PARTICIPANTS: Eligible patients were 65 years of age with three or more chronic conditions and five or more long term medications. IN …
Neurons and glial cells acquire a senescent signature after repeated mild traumatic brain injury in a sex-dependent manner.
Schwab N, Taskina D, Leung E, Innes BT, Bader GD, Hazrati LN. Schwab N, et al. Front Neurosci. 2022 Nov 3;16:1027116. doi: 10.3389/fnins.2022.1027116. eCollection 2022. Front Neurosci. 2022. PMID: 36408415 Free PMC article.
Mild traumatic brain injury (mTBI) is an important public health issue, as it can lead to long-term neurological symptoms and risk of neurodegenerative disease. ...
Mild traumatic brain injury (mTBI) is an important public health issue, as it can lead to long-term neurological symptoms and risk of …
Data Sharing and Reuse: A Method by the AIRR Community.
Corrie BD, Christley S, Busse CE, Cowell LG, Neller KCM, Rubelt F, Schwab N; AIRR Community. Corrie BD, et al. Among authors: schwab n. Methods Mol Biol. 2022;2453:447-476. doi: 10.1007/978-1-0716-2115-8_23. Methods Mol Biol. 2022. PMID: 35622339 Free PMC article.
The basis for this is the MiAIRR data standard (Rubelt et al. Nat Immunol 18:1274-1278, 2017). For long-term preservation, it is recommended that researchers store their sequence read data in an INSDC repository. ...
The basis for this is the MiAIRR data standard (Rubelt et al. Nat Immunol 18:1274-1278, 2017). For long-term preservation, it is reco …
Long-term risk of adverse outcomes according to atrial fibrillation type.
Blum S, Aeschbacher S, Coslovsky M, Meyre PB, Reddiess P, Ammann P, Erne P, Moschovitis G, Di Valentino M, Shah D, Schläpfer J, Müller R, Beer JH, Kobza R, Bonati LH, Moutzouri E, Rodondi N, Meyer-Zürn C, Kühne M, Sticherling C, Osswald S, Conen D; BEAT-AF and Swiss-AF investigators. Blum S, et al. Sci Rep. 2022 Feb 9;12(1):2208. doi: 10.1038/s41598-022-05688-9. Sci Rep. 2022. PMID: 35140237 Free PMC article.
Sustained forms of atrial fibrillation (AF) may be associated with a higher risk of adverse outcomes, but few if any long-term studies took into account changes of AF type and co-morbidities over time. ...
Sustained forms of atrial fibrillation (AF) may be associated with a higher risk of adverse outcomes, but few if any long-term studie …
Cellular Senescence in Traumatic Brain Injury: Evidence and Perspectives.
Schwab N, Leung E, Hazrati LN. Schwab N, et al. Front Aging Neurosci. 2021 Sep 28;13:742632. doi: 10.3389/fnagi.2021.742632. eCollection 2021. Front Aging Neurosci. 2021. PMID: 34650425 Free PMC article. Review.
Mild traumatic brain injury (mTBI) can lead to long-term neurological dysfunction and increase one's risk of neurodegenerative disease. ...
Mild traumatic brain injury (mTBI) can lead to long-term neurological dysfunction and increase one's risk of neurodegenerative diseas …
Optimizing Therapy to Prevent Avoidable Hospital Admissions in Multimorbid Older Adults (OPERAM): cluster randomised controlled trial.
Blum MR, Sallevelt BTGM, Spinewine A, O'Mahony D, Moutzouri E, Feller M, Baumgartner C, Roumet M, Jungo KT, Schwab N, Bretagne L, Beglinger S, Aubert CE, Wilting I, Thevelin S, Murphy K, Huibers CJA, Drenth-van Maanen AC, Boland B, Crowley E, Eichenberger A, Meulendijk M, Jennings E, Adam L, Roos MJ, Gleeson L, Shen Z, Marien S, Meinders AJ, Baretella O, Netzer S, de Montmollin M, Fournier A, Mouzon A, O'Mahony C, Aujesky D, Mavridis D, Byrne S, Jansen PAF, Schwenkglenks M, Spruit M, Dalleur O, Knol W, Trelle S, Rodondi N. Blum MR, et al. Among authors: schwab n. BMJ. 2021 Jul 13;374:n1585. doi: 10.1136/bmj.n1585. BMJ. 2021. PMID: 34257088 Free PMC article. Clinical Trial.
PARTICIPANTS: 2008 older adults (70 years) with multimorbidity (3 chronic conditions) and polypharmacy (5 drugs used long term). INTERVENTION: Clinical staff clusters were randomised to usual care or a structured pharmacotherapy optimisation intervention performed at the i …
PARTICIPANTS: 2008 older adults (70 years) with multimorbidity (3 chronic conditions) and polypharmacy (5 drugs used long term). INTE …
Early onset senescence and cognitive impairment in a murine model of repeated mTBI.
Schwab N, Ju Y, Hazrati LN. Schwab N, et al. Acta Neuropathol Commun. 2021 May 8;9(1):82. doi: 10.1186/s40478-021-01190-x. Acta Neuropathol Commun. 2021. PMID: 33964983 Free PMC article.
Senescence has been proposed to promote neurodegeneration and appears as an effective target to prevent long-term complications of mTBI, such as chronic traumatic encephalopathy and other related neurodegenerative pathologies....
Senescence has been proposed to promote neurodegeneration and appears as an effective target to prevent long-term complications of mT …
Four-corner arthrodesis of the wrist using Variable Angle Locking Compression Intercarpal Fusion Plate (VA LCP ICF Plate; Synthes()): pre- and postoperative radiological analysis and clinical outcome in long-term evaluation.
Eder C, Scheller A, Schwab N, Krapohl BD. Eder C, et al. Among authors: schwab n. GMS Interdiscip Plast Reconstr Surg DGPW. 2019 Nov 15;8:Doc15. doi: 10.3205/iprs000141. eCollection 2019. GMS Interdiscip Plast Reconstr Surg DGPW. 2019. PMID: 31815084 Free PMC article.
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