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Leveraging low-cost sensors to predict nitrogen dioxide for epidemiologic exposure assessment.
Zuidema C, Bi J, Burnham D, Carmona N, Gassett AJ, Slager DL, Schumacher C, Austin E, Seto E, Szpiro AA, Sheppard L. Zuidema C, et al. Among authors: schumacher c. J Expo Sci Environ Epidemiol. 2024 Apr 9. doi: 10.1038/s41370-024-00667-w. Online ahead of print. J Expo Sci Environ Epidemiol. 2024. PMID: 38589565
METHODS: We developed a spatiotemporal NO(2) model for the study region incorporating data from 11 agency locations, 364 supplementary monitoring locations, and 117 low-cost sensor (LCS) locations for the 1996-2020 time period. Model features included long-term time trends …
METHODS: We developed a spatiotemporal NO(2) model for the study region incorporating data from 11 agency locations, 364 supplementary monit …
Evaluating low-cost monitoring designs for PM2.5 exposure assessment with a spatiotemporal modeling approach.
Bi J, Burnham D, Zuidema C, Schumacher C, Gassett AJ, Szpiro AA, Kaufman JD, Sheppard L. Bi J, et al. Among authors: schumacher c. Environ Pollut. 2024 Feb 15;343:123227. doi: 10.1016/j.envpol.2023.123227. Epub 2023 Dec 24. Environ Pollut. 2024. PMID: 38147948
We investigated features of fixed-site LCM designs that most impact PM(2.5) exposure estimates to be used in long-term epidemiological inference for the Adult Changes in Thought Air Pollution (ACT-AP) study. ...
We investigated features of fixed-site LCM designs that most impact PM(2.5) exposure estimates to be used in long-term epidemiologica …
CYP11B2 inhibitor dexfadrostat phosphate suppresses the aldosterone-to-renin ratio, an indicator of sodium retention, in healthy volunteers.
Mulatero P, Groessl M, Vogt B, Schumacher C, Steele RE, Brooks A, Hossack S, Brunner HR. Mulatero P, et al. Among authors: schumacher c. Br J Clin Pharmacol. 2023 Aug;89(8):2483-2496. doi: 10.1111/bcp.15713. Epub 2023 Apr 10. Br J Clin Pharmacol. 2023. PMID: 36914591 Clinical Trial.
AIMS: High aldosterone is a key driver of hypertension and long-term negative sequelae. We evaluated the safety and efficacy of dexfadrostat phosphate (DP13), a novel aldosterone synthase (CYP11B2) inhibitor, in healthy participants. ...
AIMS: High aldosterone is a key driver of hypertension and long-term negative sequelae. We evaluated the safety and efficacy of dexfa …
Evaluating effects of the structural reform of outpatient psychotherapy for patients with mental disorders in Germany: comparing patients with and without comorbid chronic physical condition - rationale and study protocol of the ES-RiP project.
Kampling H, Kruse J, Friederich HC, Heuft G, Christoffer A, Grobe TG, Marschall U, Szecsenyi J, Wild B, Hartmann M; ES-RiP-Consortium Study Group. Kampling H, et al. BMJ Open. 2022 Sep 2;12(9):e057298. doi: 10.1136/bmjopen-2021-057298. BMJ Open. 2022. PMID: 36691158 Free PMC article.
The reform included new service elements, such as the implementation of additional psychotherapeutic consultations, acute short-term psychotherapeutic interventions and relapse prophylaxis as well as the promotion of group therapies, the facilitation of psychotherapists' a …
The reform included new service elements, such as the implementation of additional psychotherapeutic consultations, acute short-term …
Impact of stromal tumor-infiltrating lymphocytes (sTILs) on response to neoadjuvant chemotherapy in triple-negative early breast cancer in the WSG-ADAPT TN trial.
Kolberg-Liedtke C, Feuerhake F, Garke M, Christgen M, Kates R, Grischke EM, Forstbauer H, Braun M, Warm M, Hackmann J, Uleer C, Aktas B, Schumacher C, Kuemmel S, Wuerstlein R, Graeser M, Nitz U, Kreipe H, Gluz O, Harbeck N. Kolberg-Liedtke C, et al. Among authors: schumacher c. Breast Cancer Res. 2022 Sep 2;24(1):58. doi: 10.1186/s13058-022-01552-w. Breast Cancer Res. 2022. PMID: 36056374 Free PMC article. Clinical Trial.
CONCLUSION: The independent impact of sTILs on iDFS suggests that favorable immune response can influence key tumor biological processes for long-term survival. The results suggest that the reliability of pCR following neoadjuvant therapy as a surrogate for survival could …
CONCLUSION: The independent impact of sTILs on iDFS suggests that favorable immune response can influence key tumor biological processes for …
Primary care-based follow-up for prostate and kidney cancer survivors: a retrospective monocentric study.
Gaillard V, Tricard T, Rebel S, Schumacher C, Saussine C, Somme G, Lang H. Gaillard V, et al. Among authors: schumacher c. Support Care Cancer. 2022 Sep;30(9):7293-7302. doi: 10.1007/s00520-022-07151-x. Epub 2022 May 23. Support Care Cancer. 2022. PMID: 35604498
PURPOSE: New follow-up models of care are needed to ensure long-term comprehensive care for cancer survivors. We investigated the impact of a general practitioner (GP)-led follow-up program for prostate cancer (PCa) and renal cell cancer (RCC) survivors. ...
PURPOSE: New follow-up models of care are needed to ensure long-term comprehensive care for cancer survivors. We investigated the imp …
Functional recovery following hospitalisation of patients diagnosed with COVID-19: a protocol for a longitudinal cohort study.
Reid JC, Costa AP, Duong M, Ho T, Kruisselbrink R, Raina P, Kirkwood R, Jones A, Corriveau S, Griffith LE, Haider S, Marcucci M, Markle-Reid M, Morrison H, Raghavan N, Schumacher C, Vrkljan B, Junek M, Martin L, Patel A, Girolametto C, Pitre T, Beauchamp MK; COREG Investigators. Reid JC, et al. Among authors: schumacher c. BMJ Open. 2021 Dec 13;11(12):e053021. doi: 10.1136/bmjopen-2021-053021. BMJ Open. 2021. PMID: 34903545 Free PMC article.
The primary aim of the Coronavirus Registry Functional Recovery (COREG-FR) study is to understand the trajectory of functional recovery among individuals hospitalised for COVID-19 over the medium (up to 6 months) and longer term (6-12 months) that will guide clinical care …
The primary aim of the Coronavirus Registry Functional Recovery (COREG-FR) study is to understand the trajectory of functional recovery amon …
TP53 mutations are associated with primary endocrine resistance in luminal early breast cancer.
Grote I, Bartels S, Kandt L, Bollmann L, Christgen H, Gronewold M, Raap M, Lehmann U, Gluz O, Nitz U, Kuemmel S, Zu Eulenburg C, Braun M, Aktas B, Grischke EM, Schumacher C, Luedtke-Heckenkamp K, Kates R, Wuerstlein R, Graeser M, Harbeck N, Christgen M, Kreipe H. Grote I, et al. Among authors: schumacher c. Cancer Med. 2021 Dec;10(23):8581-8594. doi: 10.1002/cam4.4376. Epub 2021 Nov 14. Cancer Med. 2021. PMID: 34779146 Free PMC article.
METHODS: In this study, 622 estrogen receptor-expressing breast cancer cases treated with short-term preoperative endocrine therapy (pET) from the WSG-ADAPT trial (NCT01779206) were analyzed for genetic alterations associated with impaired endocrine proliferative response …
METHODS: In this study, 622 estrogen receptor-expressing breast cancer cases treated with short-term preoperative endocrine therapy ( …
Effect of Celecoxib vs Placebo as Adjuvant Therapy on Disease-Free Survival Among Patients With Breast Cancer: The REACT Randomized Clinical Trial.
Coombes RC, Tovey H, Kilburn L, Mansi J, Palmieri C, Bartlett J, Hicks J, Makris A, Evans A, Loibl S, Denkert C, Murray E, Grieve R, Coleman R, Borley A, Schmidt M, Rautenberg B, Kunze CA, Rhein U, Mehta K, Mousa K, Dibble T, Lu XL, von Minckwitz G, Bliss JM; Randomized European Celecoxib Trial (REACT) Trial Management Group and Investigators. Coombes RC, et al. JAMA Oncol. 2021 Sep 1;7(9):1291-1301. doi: 10.1001/jamaoncol.2021.2193. JAMA Oncol. 2021. PMID: 34264305 Free PMC article. Clinical Trial.
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, patients showed no evidence of a DFS benefit for 2 years' treatment with celecoxib compared with placebo as adjuvant treatment of ERBB2-negative breast cancer. Longer-term treatment or use of a higher dose of ce …
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, patients showed no evidence of a DFS benefit for 2 years' treatment with celec …
Deployment, Calibration, and Cross-Validation of Low-Cost Electrochemical Sensors for Carbon Monoxide, Nitrogen Oxides, and Ozone for an Epidemiological Study.
Zuidema C, Schumacher CS, Austin E, Carvlin G, Larson TV, Spalt EW, Zusman M, Gassett AJ, Seto E, Kaufman JD, Sheppard L. Zuidema C, et al. Among authors: schumacher cs. Sensors (Basel). 2021 Jun 19;21(12):4214. doi: 10.3390/s21124214. Sensors (Basel). 2021. PMID: 34205429 Free PMC article.
Monitors were rotated throughout the region, including at two Puget Sound Clean Air Agency monitoring sites for calibration purposes, and over 100 residences, including the homes of epidemiological study participants, with the goal of improving long-term pollutant exposure …
Monitors were rotated throughout the region, including at two Puget Sound Clean Air Agency monitoring sites for calibration purposes, and ov …
36 results