Effect of treatment with dornase alpha on airway inflammation in patients with cystic fibrosis.
Paul K, Rietschel E, Ballmann M, Griese M, Worlitzsch D, Shute J, Chen C, Schink T, Döring G, van Koningsbruggen S, Wahn U, Ratjen F; Bronchoalveolar Lavage for the Evaluation of Antiinflammatory Treatment Study Group.
Paul K, et al. Among authors: schink t.
Am J Respir Crit Care Med. 2004 Mar 15;169(6):719-25. doi: 10.1164/rccm.200307-959OC. Epub 2003 Dec 18.
Am J Respir Crit Care Med. 2004.
PMID: 14684561
Clinical Trial.
Recombinant human deoxyribonuclease (rhDNase) has been shown to improve lung function and reduce the number of pulmonary exacerbations in patients with cystic fibrosis (CF), but its long-term effect on airway inflammation remains unknown. In this study, we used bronchoalve …
Recombinant human deoxyribonuclease (rhDNase) has been shown to improve lung function and reduce the number of pulmonary exacerbations in pa …