Sunitinib represses regulatory T cells to overcome immunotolerance in a murine model of hepatocellular cancer.
Liu D, Li G, Avella DM, Kimchi ET, Kaifi JT, Rubinstein MP, Camp ER, Rockey DC, Schell TD, Staveley-O'Carroll KF.
Liu D, et al. Among authors: schell td.
Oncoimmunology. 2017 Sep 21;7(1):e1372079. doi: 10.1080/2162402X.2017.1372079. eCollection 2017.
Oncoimmunology. 2017.
PMID: 29296523
Free PMC article.
Importantly, the additional integration of exogenous naive TAS CD8(+) T cells by adoptive cell transfer (ACT) leads to the elimination of the established tumors without recurrence and promotes long-term survival of the treated mice. Mechanistically, sunitinib treatment pri …
Importantly, the additional integration of exogenous naive TAS CD8(+) T cells by adoptive cell transfer (ACT) leads to the elimination of th …