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Blood CD9+ B cell, a biomarker of bronchiolitis obliterans syndrome after lung transplantation.
Brosseau C, Danger R, Durand M, Durand E, Foureau A, Lacoste P, Tissot A, Roux A, Reynaud-Gaubert M, Kessler R, Mussot S, Dromer C, Brugière O, Mornex JF, Guillemain R, Claustre J, Magnan A, Brouard S; COLT and SysCLAD Consortia. Brosseau C, et al. Am J Transplant. 2019 Nov;19(11):3162-3175. doi: 10.1111/ajt.15532. Epub 2019 Aug 21. Am J Transplant. 2019. PMID: 31305014 Free article.
Bronchiolitis obliterans syndrome is the main limitation for long-term survival after lung transplantation. Some specific B cell populations are associated with long-term graft acceptance. ...CD9-expressing B cells appear as a contributor to a favorable environment …
Bronchiolitis obliterans syndrome is the main limitation for long-term survival after lung transplantation. Some specific B cell popu …
Normothermic ex-vivo preservation with the portable Organ Care System Lung device for bilateral lung transplantation (INSPIRE): a randomised, open-label, non-inferiority, phase 3 study.
Warnecke G, Van Raemdonck D, Smith MA, Massard G, Kukreja J, Rea F, Loor G, De Robertis F, Nagendran J, Dhital KK, Moradiellos Díez FJ, Knosalla C, Bermudez CA, Tsui S, McCurry K, Wang IW, Deuse T, Lesèche G, Thomas P, Tudorache I, Kühn C, Avsar M, Wiegmann B, Sommer W, Neyrinck A, Schiavon M, Calabrese F, Santelmo N, Olland A, Falcoz PE, Simon AR, Varela A, Madsen JC, Hertz M, Haverich A, Ardehali A. Warnecke G, et al. Among authors: santelmo n. Lancet Respir Med. 2018 May;6(5):357-367. doi: 10.1016/S2213-2600(18)30136-X. Epub 2018 Apr 9. Lancet Respir Med. 2018. PMID: 29650408 Clinical Trial.
INTERPRETATION: The INSPIRE trial met its primary effectiveness and safety endpoints. Although no short-term survival benefit was reported, further research is needed to see whether the reduced incidence of PGD3 within 72 h of a transplant might translate into earlier reco …
INTERPRETATION: The INSPIRE trial met its primary effectiveness and safety endpoints. Although no short-term survival benefit was rep …
Blood Gene Expression Predicts Bronchiolitis Obliterans Syndrome.
Danger R, Royer PJ, Reboulleau D, Durand E, Loy J, Tissot A, Lacoste P, Roux A, Reynaud-Gaubert M, Gomez C, Kessler R, Mussot S, Dromer C, Brugière O, Mornex JF, Guillemain R, Dahan M, Knoop C, Botturi K, Foureau A, Pison C, Koutsokera A, Nicod LP, Brouard S, Magnan A; COLT and SysCLAD Consortia. Danger R, et al. Front Immunol. 2018 Jan 11;8:1841. doi: 10.3389/fimmu.2017.01841. eCollection 2017. Front Immunol. 2018. PMID: 29375549 Free PMC article.
Bronchiolitis obliterans syndrome (BOS), the main manifestation of chronic lung allograft dysfunction, leads to poor long-term survival after lung transplantation. Identifying predictors of BOS is essential to prevent the progression of dysfunction before irreversible dama …
Bronchiolitis obliterans syndrome (BOS), the main manifestation of chronic lung allograft dysfunction, leads to poor long-term surviv …
Airway microbiota signals anabolic and catabolic remodeling in the transplanted lung.
Mouraux S, Bernasconi E, Pattaroni C, Koutsokera A, Aubert JD, Claustre J, Pison C, Royer PJ, Magnan A, Kessler R, Benden C, Soccal PM, Marsland BJ, Nicod LP; SysCLAD Consortium. Mouraux S, et al. J Allergy Clin Immunol. 2018 Feb;141(2):718-729.e7. doi: 10.1016/j.jaci.2017.06.022. Epub 2017 Jul 18. J Allergy Clin Immunol. 2018. PMID: 28729000 Free PMC article. Clinical Trial.
BACKGROUND: Homeostatic turnover of the extracellular matrix conditions the structure and function of the healthy lung. In lung transplantation, long-term management remains limited by chronic lung allograft dysfunction, an umbrella term used for a heterogeneous ent …
BACKGROUND: Homeostatic turnover of the extracellular matrix conditions the structure and function of the healthy lung. In lung transplantat …
Early and Late Atrial Arrhythmias After Lung Transplantation - Incidence, Predictive Factors and Impact on Mortality.
Jesel L, Barraud J, Lim HS, Marzak H, Messas N, Hirschi S, Santelmo N, Olland A, Falcoz PE, Massard G, Kindo M, Ohlmann P, Chauvin M, Morel O, Kessler R. Jesel L, et al. Among authors: santelmo n. Circ J. 2017 Apr 25;81(5):660-667. doi: 10.1253/circj.CJ-16-0892. Epub 2017 Feb 15. Circ J. 2017. PMID: 28202855 Free article.
Pretransplant systolic pulmonary arterial pressure (PTsPAP) was the only independent predictive factor of late AA (OR 1.028; CI [1.001-1.056]; P=0.04). Double LT was associated with long-term freedom from atrial fibrillation (AF) but not from atrial flutter (AFL). ...
Pretransplant systolic pulmonary arterial pressure (PTsPAP) was the only independent predictive factor of late AA (OR 1.028; CI [1.001-1.056 …
T Cells Promote Bronchial Epithelial Cell Secretion of Matrix Metalloproteinase-9 via a C-C Chemokine Receptor Type 2 Pathway: Implications for Chronic Lung Allograft Dysfunction.
Pain M, Royer PJ, Loy J, Girardeau A, Tissot A, Lacoste P, Roux A, Reynaud-Gaubert M, Kessler R, Mussot S, Dromer C, Brugière O, Mornex JF, Guillemain R, Dahan M, Knoop C, Botturi K, Pison C, Danger R, Brouard S, Magnan A; COLT Consortium. Pain M, et al. Am J Transplant. 2017 Jun;17(6):1502-1514. doi: 10.1111/ajt.14166. Epub 2017 Jan 23. Am J Transplant. 2017. PMID: 27982503 Free article.
Chronic lung allograft dysfunction (CLAD) is the major limitation of long-term survival after lung transplantation. CLAD manifests as bronchiolitis obliterans syndrome (BOS) or restrictive allograft syndrome (RAS). ...
Chronic lung allograft dysfunction (CLAD) is the major limitation of long-term survival after lung transplantation. CLAD manifests as …
Vascular access for extracorporeal life support: tips and tricks.
Reeb J, Olland A, Renaud S, Lejay A, Santelmo N, Massard G, Falcoz PE. Reeb J, et al. Among authors: santelmo n. J Thorac Dis. 2016 Apr;8(Suppl 4):S353-63. doi: 10.21037/jtd.2016.04.42. J Thorac Dis. 2016. PMID: 27195133 Free PMC article. Review.
In thoracic surgery, extracorporeal life support (ECLS) techniques are performed to (I) provide a short to mid term extracorporeal mechanical support; (II) realize the gas exchanges; and (III)-depending the configuration of the circuit-substitute the failed heart function. …
In thoracic surgery, extracorporeal life support (ECLS) techniques are performed to (I) provide a short to mid term extracorporeal me …
Comparative study for surgical management of thymectomy for non-thymomatous myasthenia gravis from the French national database EPITHOR.
Orsini B, Santelmo N, Pages PB, Baste JM, Dahan M, Bernard A, Thomas PA; EPITHOR project (French Society of Thoracic and Cardiovascular surgery). Orsini B, et al. Among authors: santelmo n. Eur J Cardiothorac Surg. 2016 Sep;50(3):418-22. doi: 10.1093/ejcts/ezw064. Epub 2016 Mar 16. Eur J Cardiothorac Surg. 2016. PMID: 26984980
We investigated the postoperative morbidity and mortality without analysis of the long-term evolution of the disease not available on EPITHOR. RESULTS: From 2005 to 2013, 278 patients were included: 131 (47%) in Group A, 31 (11%) in Group B and 116 (42%) in Group C. ...
We investigated the postoperative morbidity and mortality without analysis of the long-term evolution of the disease not available on …
Does nodal status influence survival? Results of a 19-year systematic lymphadenectomy experience during lung metastasectomy of colorectal cancer.
Renaud S, Alifano M, Falcoz PE, Magdeleinat P, Santelmo N, Pagès O, Massard G, Régnard JF. Renaud S, et al. Among authors: santelmo n. Interact Cardiovasc Thorac Surg. 2014 Apr;18(4):482-7. doi: 10.1093/icvts/ivt554. Epub 2014 Jan 16. Interact Cardiovasc Thorac Surg. 2014. PMID: 24442624 Free PMC article.
OBJECTIVES: Resection of pulmonary metastases originating from colorectal cancer is increasingly considered. While several adverse risk factors for long-term outcome are known, the selection of patients who may benefit from surgery remains unclear. ...
OBJECTIVES: Resection of pulmonary metastases originating from colorectal cancer is increasingly considered. While several adverse risk fact …
Does surgical stabilization improve outcomes in patients with isolated multiple distracted and painful non-flail rib fractures?
Girsowicz E, Falcoz PE, Santelmo N, Massard G. Girsowicz E, et al. Among authors: santelmo n. Interact Cardiovasc Thorac Surg. 2012 Mar;14(3):312-5. doi: 10.1093/icvts/ivr028. Epub 2011 Dec 21. Interact Cardiovasc Thorac Surg. 2012. PMID: 22190569 Free PMC article.
Indeed, most of the authors justified surgical management based on the fact that the results of surgical stabilization showed improvement in short- and long-term patient outcomes, with fast reduction in pain and disability, as well as lower average wait before recommencing …
Indeed, most of the authors justified surgical management based on the fact that the results of surgical stabilization showed improvement in …
16 results