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Factors Related to Favorable Outcomes in Older Adults Undergoing Home-Visit Rehabilitation Therapy.
Nakagawa Y, Goda A, Fujii K, Shimazaki R, Orita N, Yoshino D, Kawara T, Sakurai M, Ito Y, Maki Y. Nakagawa Y, et al. Among authors: sakurai m. Cureus. 2024 Feb 6;16(2):e53740. doi: 10.7759/cureus.53740. eCollection 2024 Feb. Cureus. 2024. PMID: 38465166 Free PMC article.
The initial and final clinical variables evaluated in this study included the abilities of daily living, degree of being bedridden, dementia rating, and levels of support or long-term care. Those variables were evaluated by rehabilitation therapists and doctors. ...
The initial and final clinical variables evaluated in this study included the abilities of daily living, degree of being bedridden, dementia …
Ex vivo expansion of human hematopoietic stem cells and clinical applications.
Sakurai M, Ishitsuka K, Becker HJ, Yamazaki S. Sakurai M, et al. Cancer Sci. 2024 Mar;115(3):698-705. doi: 10.1111/cas.16066. Epub 2024 Jan 14. Cancer Sci. 2024. PMID: 38221718 Free PMC article. Review.
However, in recent years, the development of a technique in which small molecules are added to cytokines has enabled the stable, long-term ex vivo expansion of human HSCs. Clinical trials of expanded umbilical CB using these techniques have been undertaken and have confirm …
However, in recent years, the development of a technique in which small molecules are added to cytokines has enabled the stable, long-ter …
Recent advances in ex vivo expansion of human hematopoietic stem cells.
Sakurai M. Sakurai M. Blood Cell Ther. 2023 Nov 25;6(4):151-157. doi: 10.31547/bct-2023-026. eCollection 2023 Nov 25. Blood Cell Ther. 2023. PMID: 38149022 Free PMC article.
Recent advances that include the addition of small molecules to cytokines have enabled long-term and stable ex vivo expansion of human HSCs. Clinical trials have been conducted with HSCs expanded in CB using these techniques, confirming their efficacy and safety. Furthermo …
Recent advances that include the addition of small molecules to cytokines have enabled long-term and stable ex vivo expansion of huma …
Activation of the Akt signalling pathway as a prognostic indicator in canine soft tissue sarcoma.
Miyanishi K, Nururrozi A, Igase M, Tanabe M, Sakurai M, Sakai Y, Shimonohara N, Murakami M, Mizuno T. Miyanishi K, et al. Among authors: sakurai m. J Comp Pathol. 2023 Oct;206:44-52. doi: 10.1016/j.jcpa.2023.08.007. Epub 2023 Oct 13. J Comp Pathol. 2023. PMID: 37839309
Canine soft tissue sarcoma (STS) is relatively common in dogs and is the generic term for tumours that originate from mesenchymal cells. While histopathological grade and immunolabelling with Ki-67 have been used for estimating prognosis, additional indicators are needed f …
Canine soft tissue sarcoma (STS) is relatively common in dogs and is the generic term for tumours that originate from mesenchymal cel …
Cost-effectiveness of left atrial appendage closure with Watchman for non-valvular atrial fibrillation patients in Japan.
Kamae I, Zhong Y, Hara H, Inoue K, Yasaka M, Reddy VY, Holmes DR, Sakurai M, Gavaghan MB, Amorosi SL, McGovern AM, Priest V, Inoue S, Shibahara H, Akehurst RL. Kamae I, et al. Among authors: sakurai m. J Med Econ. 2023 Jan-Dec;26(1):1357-1367. doi: 10.1080/13696998.2023.2266275. Epub 2023 Oct 27. J Med Econ. 2023. PMID: 37819734 Free article.
Further, LAAC contributed an additional 1.500 quality-adjusted life years (QALYs) compared to warfarin and 0.996 QALYs compared to DOACs. In the long-term, adopting LAAC as an alternative to warfarin and DOACs is a cost-effective strategy for reducing stroke risk in NVAF p …
Further, LAAC contributed an additional 1.500 quality-adjusted life years (QALYs) compared to warfarin and 0.996 QALYs compared to DOACs. In …
Current Situation and Causes Analysis of Cadmium Pollution in the Kakehashi River Basin.
Sun XL, Okamoto R, Phuc HD, Kido T, Oanh NTP, Nakada A, Nogawa K, Suwazono Y, Nakagawa H, Sakurai M. Sun XL, et al. Among authors: sakurai m. Biol Trace Elem Res. 2024 May;202(5):2036-2041. doi: 10.1007/s12011-023-03827-5. Epub 2023 Aug 29. Biol Trace Elem Res. 2024. PMID: 37642812
Cadmium (Cd) pollution is a public environmental problem worthy of attention. Long-term exposure to Cd may have adverse effects on human health. Our previous study showed that urinary concentration of Cd (U-Cd) in the residents decreased when Cd-polluted paddy soil was rem …
Cadmium (Cd) pollution is a public environmental problem worthy of attention. Long-term exposure to Cd may have adverse effects on hu …
Successful Production of Offspring Derived from Phospholipase C Zeta-Deficient Sperm by Additional Artificial Activation.
Hirose N, Kikuchi Y, Kageyama A, Sugita H, Sakurai M, Kawata Y, Terakawa J, Wakayama T, Ito J, Kashiwazaki N. Hirose N, et al. Among authors: sakurai m. Life (Basel). 2023 Apr 10;13(4):980. doi: 10.3390/life13040980. Life (Basel). 2023. PMID: 37109509 Free PMC article.
In this study, we examined whether oocytes injected with a Plcz1(-/-) sperm can develop to term by additional artificial activation. In oocytes injected a Plcz1(-/-) sperm and Plcz1(-/-) and eCS (another candidate of the sperm factor) double knockout sperm (Plcz1(-/-)eCS(- …
In this study, we examined whether oocytes injected with a Plcz1(-/-) sperm can develop to term by additional artificial activation. …
A case of vasoactive intestinal peptide-secreting tumor (VIPoma) arising from MEN1 inactivation which recurred 15 years after the initial resection.
Sakurai M, Wakabayashi T, Kondo Y, Ikeda E, Watanabe K, Takei A, Okazaki H, Okada K, Ebihara K, Kakiuchi N, Ogawa S, Fukushima N, Ishibashi S. Sakurai M, et al. Endocr J. 2023 Jun 28;70(6):573-579. doi: 10.1507/endocrj.EJ22-0578. Epub 2023 Mar 9. Endocr J. 2023. PMID: 36889692 Free article.
Here, we report the case of a 51-year-old female patient with VIPoma that recurred after a long-term disease-free interval. This patient had been asymptomatic for approximately 15 years after the initial curative surgery for pancreatic VIPoma, with no metastasis. ...The pa …
Here, we report the case of a 51-year-old female patient with VIPoma that recurred after a long-term disease-free interval. This pati …
Chemically defined cytokine-free expansion of human haematopoietic stem cells.
Sakurai M, Ishitsuka K, Ito R, Wilkinson AC, Kimura T, Mizutani E, Nishikii H, Sudo K, Becker HJ, Takemoto H, Sano T, Kataoka K, Takahashi S, Nakamura Y, Kent DG, Iwama A, Chiba S, Okamoto S, Nakauchi H, Yamazaki S. Sakurai M, et al. Nature. 2023 Mar;615(7950):127-133. doi: 10.1038/s41586-023-05739-9. Epub 2023 Feb 22. Nature. 2023. PMID: 36813966 Free article.
Here we report the establishment of a culture system that allows the long-term ex vivo expansion of human HSCs, achieved through the complete replacement of exogenous cytokines and albumin with chemical agonists and a caprolactam-based polymer. ...
Here we report the establishment of a culture system that allows the long-term ex vivo expansion of human HSCs, achieved through the …
131 results