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Treatment results of carotid artery stenting with an open-cell stent: Analysis of 734 consecutive cases at a single center.
Omura Y, Imamura H, Tani S, Adachi H, Sakaguchi M, Todo K, Yamagami H, Goto M, Ohara N, Fukumitsu R, Sunohara T, Matsumoto S, Fukui N, Fukuda T, Akiyama T, Ohta T, Sakai C, Sakai N. Omura Y, et al. Among authors: sakai n. World Neurosurg. 2024 Apr 23:S1878-8750(24)00681-8. doi: 10.1016/j.wneu.2024.04.108. Online ahead of print. World Neurosurg. 2024. PMID: 38663734
Thus, 734 patients were retrospectively analyzed. Perioperative and long-term outcomes and risk factors for perioperative infarction were investigated. ...CONCLUSION: CAS with open-cell stents showed good results in terms of both the postoperative stroke incidence and long …
Thus, 734 patients were retrospectively analyzed. Perioperative and long-term outcomes and risk factors for perioperative infarction …
Abnormal bone regeneration induced by FK506 in medaka fin revealed by in vivo imaging.
Otake K, Azetsu Y, Chatani M, Karakawa A, Nishida S, Hirayama A, Kobayashi R, Sakai N, Suzuki N, Takami M. Otake K, et al. Among authors: sakai n. J Oral Biosci. 2024 Feb 27:S1349-0079(24)00020-3. doi: 10.1016/j.job.2024.02.007. Online ahead of print. J Oral Biosci. 2024. PMID: 38423180
CONCLUSIONS: Our findings suggest that treatment with FK506 promotes bone regeneration by increasing the number of osteoblasts in the amputated area of the fin. However, long-term treatment disrupts regular bone metabolism by inducing abnormal osteoclast formation....
CONCLUSIONS: Our findings suggest that treatment with FK506 promotes bone regeneration by increasing the number of osteoblasts in the amputa …
Allogeneic Stem Cell Therapy for Acute Ischemic Stroke: The Phase 2/3 TREASURE Randomized Clinical Trial.
Houkin K, Osanai T, Uchiyama S, Minematsu K, Taguchi A, Maruichi K, Niiya Y, Asaoka K, Kuga Y, Takizawa K, Haraguchi K, Yoshimura S, Kimura K, Tokunaga K, Aoyama A, Ikawa F, Inenaga C, Abe T, Tominaga A, Takahashi S, Kudo K, Fujimura M, Sugiyama T, Ito M, Kawabori M, Hess DC, Savitz SI, Hirano T; TREASURE Study Investigators. Houkin K, et al. JAMA Neurol. 2024 Feb 1;81(2):154-162. doi: 10.1001/jamaneurol.2023.5200. JAMA Neurol. 2024. PMID: 38227308 Free PMC article. Clinical Trial.
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, intravenous administration of allogeneic cell therapy within 18 to 36 hours of ischemic stroke onset was safe but did not improve short-term outcomes. Further research is needed to determine whether MultiStem th …
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, intravenous administration of allogeneic cell therapy within 18 to 36 hours of …
Eosinophil Involvement Outside the Esophagus in Eosinophilic Esophagitis.
Sato H, Taylor RJ, Sakai N, Osonoi K, Rothenberg ME, Shoda T. Sato H, et al. Among authors: sakai n. Clin Gastroenterol Hepatol. 2023 Dec 15:S1542-3565(23)01034-0. doi: 10.1016/j.cgh.2023.12.004. Online ahead of print. Clin Gastroenterol Hepatol. 2023. PMID: 38103874
Notably, in a survey of these experts, 61% agreed with the later term "non-EoE EGID with EI," because EoE is isolated to the esophagus by current diagnostic criteria.(3) However, limited molecular and pathogenic data exist to support the distinction. ...
Notably, in a survey of these experts, 61% agreed with the later term "non-EoE EGID with EI," because EoE is isolated to the esophagu …
In Vitro Storage of Functional Sperm at Room Temperature in Zebrafish and Medaka.
Takemoto K, Nishimura T, Kawasaki T, Imai Y, Levy K, Hart N, Olaya I, Burgess SM, Elkouby YM, Tanaka M, Sakai N. Takemoto K, et al. Among authors: sakai n. Zebrafish. 2023 Dec;20(6):229-235. doi: 10.1089/zeb.2023.0054. Epub 2023 Nov 20. Zebrafish. 2023. PMID: 38010808
The longevity of sperm in teleost such as zebrafish and medaka is short when isolated even in saline-balanced solution at a physiological temperature. In contrast, some internal fertilizers exhibit the long-term storage of sperm, >10 months, in the female reproductive t …
The longevity of sperm in teleost such as zebrafish and medaka is short when isolated even in saline-balanced solution at a physiological te …
Weight-loss Independent Clinical and Metabolic Biomarkers Associated with Type 2 Diabetes Remission Post-bariatric/metabolic Surgery.
Chaiyasoot K, Sakai NS, Zakeri R, Makaronidis J, Crisóstomo L, Alves MG, Gan W, Firman C, Jassil FC, Hall-Craggs MA, Taylor SA, Batterham RL. Chaiyasoot K, et al. Among authors: sakai ns. Obes Surg. 2023 Dec;33(12):3988-3998. doi: 10.1007/s11695-023-06905-8. Epub 2023 Nov 1. Obes Surg. 2023. PMID: 37910328 Free PMC article.
These findings suggest that adjunctive approaches that target VAT loss and restoration of BCAA metabolism might achieve higher rates of long-term T2D remission post-surgery....
These findings suggest that adjunctive approaches that target VAT loss and restoration of BCAA metabolism might achieve higher rates of long …
Cost-effectiveness of Endovascular Treatment for Acute Stroke with Large Infarct: A United States Perspective.
Ospel JM, Kunz WG, McDonough RV, Goyal M, Uchida K, Sakai N, Yamagami H, Yoshimura S; RESCUE-Japan LIMIT Investigators. Ospel JM, et al. Among authors: sakai n. Radiology. 2023 Oct;309(1):e223320. doi: 10.1148/radiol.223320. Radiology. 2023. PMID: 37787675 Clinical Trial.
The primary outcome of the current study was cost-effectiveness, determined according to the incremental cost-effectiveness ratio (ICER). A decision model consisting of a short-term component (cycle length of 3 months) and a long-term Markov state transition compone …
The primary outcome of the current study was cost-effectiveness, determined according to the incremental cost-effectiveness ratio (ICER). A …
Relation between duration of dual antiplatelet therapy and risk of ischemic stroke after stent-assisted treatment of cerebral aneurysm (DAPTS ACE-registry).
Ozaki T, Yamagami H, Morimoto M, Imamura H, Hatano T, Oishi H, Haraguchi K, Yoshimura S, Satow T, Sugiu K, Iihara K, Matsumaru Y, Hayakawa M, Matsumoto Y, Sakai C, Miyamoto S, Kitagawa K, Kagimura T, Sakai N. Ozaki T, et al. Among authors: sakai n. J Neurointerv Surg. 2023 Jul 11:jnis-2023-020495. doi: 10.1136/jnis-2023-020495. Online ahead of print. J Neurointerv Surg. 2023. PMID: 37433663
Patients who were treated with DAPT for more than 6 months (n=191) were classified as the long-term DAPT group. Those treated less than 6 months (n=105) were classified as the short-term group. The incidence of ischemic stroke did not significantly differ between th …
Patients who were treated with DAPT for more than 6 months (n=191) were classified as the long-term DAPT group. Those treated less th …
Short- versus long-term Dual AntiPlatelet Therapy for Stent-Assisted treatment of CErebral aneurysm (DAPTS ACE): a multicenter, open-label, randomized clinical trial.
Ozaki T, Yamagami H, Morimoto M, Hatano T, Oishi H, Haraguchi K, Yoshimura S, Sugiu K, Iihara K, Matsumaru Y, Matsumoto Y, Satow T, Hayakawa M, Sakai C, Miyamoto S, Kitagawa K, Daimon T, Kagimura T, Sakai N. Ozaki T, et al. Among authors: sakai n. J Neurointerv Surg. 2024 Jan 12;16(2):171-176. doi: 10.1136/jnis-2022-019867. J Neurointerv Surg. 2024. PMID: 37068941 Free PMC article. Clinical Trial.
Patients were enrolled within 30 days after SACE and assigned in a 1:1 ratio to receive long-term (12 months) or short-term (3 months) DAPT with aspirin and clopidogrel. ...Ischemic stroke occurred in no patients in the long-term DAPT group and in one patient …
Patients were enrolled within 30 days after SACE and assigned in a 1:1 ratio to receive long-term (12 months) or short-term (3 …
National trends in the outcomes of subarachnoid haemorrhage and the prognostic influence of stroke centre capability in Japan: retrospective cohort study.
Kurogi R, Kada A, Ogasawara K, Nishimura K, Kitazono T, Iwama T, Matsumaru Y, Sakai N, Shiokawa Y, Miyachi S, Kuroda S, Shimizu H, Yoshimura S, Osato T, Horie N, Nagata I, Nozaki K, Date I, Hashimoto Y, Hoshino H, Nakase H, Kataoka H, Ohta T, Fukuda H, Tamiya N, Kurogi AI, Ren N, Nishimura A, Arimura K, Shimogawa T, Yoshimoto K, Onozuka D, Ogata S, Hagihara A, Saito N, Arai H, Miyamoto S, Tominaga T, Iihara K; J-ASPECT Study Collaborators. Kurogi R, et al. Among authors: sakai n. BMJ Open. 2023 Apr 10;13(4):e068642. doi: 10.1136/bmjopen-2022-068642. BMJ Open. 2023. PMID: 37037619 Free PMC article.
CSC score improvement was associated with increased use of coiling (per 1-point increase, 1.14 (1.08 to 1.20)) but not with short-term patient outcomes regardless of treatment modality. CONCLUSIONS: The 6-year trends indicated lower in-hospital mortality for patients with …
CSC score improvement was associated with increased use of coiling (per 1-point increase, 1.14 (1.08 to 1.20)) but not with short-term …
117 results