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Page 1
Application of High-Sensitivity Troponin in Suspected Myocardial Infarction.
Neumann JT, Twerenbold R, Ojeda F, Sörensen NA, Chapman AR, Shah ASV, Anand A, Boeddinghaus J, Nestelberger T, Badertscher P, Mokhtari A, Pickering JW, Troughton RW, Greenslade J, Parsonage W, Mueller-Hennessen M, Gori T, Jernberg T, Morris N, Liebetrau C, Hamm C, Katus HA, Münzel T, Landmesser U, Salomaa V, Iacoviello L, Ferrario MM, Giampaoli S, Kee F, Thorand B, Peters A, Borchini R, Jørgensen T, Söderberg S, Sans S, Tunstall-Pedoe H, Kuulasmaa K, Renné T, Lackner KJ, Worster A, Body R, Ekelund U, Kavsak PA, Keller T, Lindahl B, Wild P, Giannitsis E, Than M, Cullen LA, Mills NL, Mueller C, Zeller T, Westermann D, Blankenberg S; COMPASS-MI Study Group. Neumann JT, et al. N Engl J Med. 2019 Jun 27;380(26):2529-2540. doi: 10.1056/NEJMoa1803377. N Engl J Med. 2019. PMID: 31242362
Lower high-sensitivity troponin concentrations at presentation and smaller absolute changes during serial sampling were associated with a lower likelihood of myocardial infarction and a lower short-term risk of cardiovascular events. For example, high-sensitivity troponin …
Lower high-sensitivity troponin concentrations at presentation and smaller absolute changes during serial sampling were associated with a lo …
Long-Term Outcomes in Patients With Type 2 Myocardial Infarction and Myocardial Injury.
Chapman AR, Shah ASV, Lee KK, Anand A, Francis O, Adamson P, McAllister DA, Strachan FE, Newby DE, Mills NL. Chapman AR, et al. Circulation. 2018 Mar 20;137(12):1236-1245. doi: 10.1161/CIRCULATIONAHA.117.031806. Epub 2017 Nov 17. Circulation. 2018. PMID: 29150426 Free PMC article.
BACKGROUND: Type 2 myocardial infarction and myocardial injury are common in clinical practice, but long-term consequences are uncertain. We aimed to define long-term outcomes and explore risk stratification in patients with type 2 myocardial infarction and myocardi …
BACKGROUND: Type 2 myocardial infarction and myocardial injury are common in clinical practice, but long-term consequences are uncert …
Assessment and classification of patients with myocardial injury and infarction in clinical practice.
Chapman AR, Adamson PD, Mills NL. Chapman AR, et al. Heart. 2017 Jan 1;103(1):10-18. doi: 10.1136/heartjnl-2016-309530. Epub 2016 Nov 2. Heart. 2017. PMID: 27806987 Free PMC article. Review.
However, both myocardial injury and type 2 myocardial infarction are common, occurring in more than one-third of all hospitalised patients. These patients have poor short-term and long-term outcomes with two-thirds dead in 5 years. The classification of patients wit …
However, both myocardial injury and type 2 myocardial infarction are common, occurring in more than one-third of all hospitalised patients. …
Stress hyperglycaemia in hospitalised patients and their 3-year risk of diabetes: a Scottish retrospective cohort study.
McAllister DA, Hughes KA, Lone N, Mills NL, Sattar N, McKnight J, Wild SH. McAllister DA, et al. PLoS Med. 2014 Aug 19;11(8):e1001708. doi: 10.1371/journal.pmed.1001708. eCollection 2014 Aug. PLoS Med. 2014. PMID: 25136809 Free PMC article.
Mortality was also 1.5-fold higher in patients with elevated glucose levels. Our findings can be used to inform patients of their long-term risk of type 2 diabetes, and to target lifestyle advice to those patients at highest risk. ...
Mortality was also 1.5-fold higher in patients with elevated glucose levels. Our findings can be used to inform patients of their long-te …
High-sensitivity troponin I concentrations are a marker of an advanced hypertrophic response and adverse outcomes in patients with aortic stenosis.
Chin CW, Shah AS, McAllister DA, Joanna Cowell S, Alam S, Langrish JP, Strachan FE, Hunter AL, Maria Choy A, Lang CC, Walker S, Boon NA, Newby DE, Mills NL, Dweck MR. Chin CW, et al. Eur Heart J. 2014 Sep 7;35(34):2312-21. doi: 10.1093/eurheartj/ehu189. Epub 2014 May 14. Eur Heart J. 2014. PMID: 24829362 Free PMC article. Clinical Trial.
We sought to investigate the mechanism for troponin release in patients with aortic stenosis and whether plasma cTnI concentrations are associated with long-term outcome. METHODS AND RESULTS: Plasma cTnI concentrations were measured in two patient cohorts using a high-sens …
We sought to investigate the mechanism for troponin release in patients with aortic stenosis and whether plasma cTnI concentrations are asso …