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Recruitment of inflammatory monocytes by senescent fibroblasts inhibits antigen-specific tissue immunity during human aging.
Chambers ES, Vukmanovic-Stejic M, Shih BB, Trahair H, Subramanian P, Devine OP, Glanville J, Gilroy D, Rustin MHA, Freeman TC, Mabbott NA, Akbar AN. Chambers ES, et al. Among authors: rustin mha. Nat Aging. 2021 Jan;1(1):101-113. doi: 10.1038/s43587-020-00010-6. Epub 2021 Jan 14. Nat Aging. 2021. PMID: 37118005
Our results point to a series of molecular and cellular mechanisms that link cellular senescence, tissue damage, excessive inflammation and reduced immune responsiveness in human skin and demonstrate that tissue-specific immunity can be restored in older adults by short-term …
Our results point to a series of molecular and cellular mechanisms that link cellular senescence, tissue damage, excessive inflammation and …
Long-term safety of biologics in the treatment of moderate-to-severe plaque psoriasis: review of current data.
Rustin MH. Rustin MH. Br J Dermatol. 2012 Nov;167 Suppl 3:3-11. doi: 10.1111/j.1365-2133.2012.11208.x. Br J Dermatol. 2012. PMID: 23082810 Review.
Although several biologics have demonstrated good efficacy and tolerability in short-term trials, treatment guidelines recommend them as third-line therapies due to a relative lack of long-term safety data. ...With the exception of efalizumab, which has been withdra …
Although several biologics have demonstrated good efficacy and tolerability in short-term trials, treatment guidelines recommend them …
The safety of tacrolimus ointment for the treatment of atopic dermatitis: a review.
Rustin MH. Rustin MH. Br J Dermatol. 2007 Nov;157(5):861-73. doi: 10.1111/j.1365-2133.2007.08177.x. Epub 2007 Sep 13. Br J Dermatol. 2007. PMID: 17854353 Review.
Moreover, TCIs are not associated with a decrease in immunocompetence in the skin and there is no increase in the incidence of infections with long-term treatment. More than 5.4 million prescriptions for tacrolimus ointment have been issued worldwide, with no evidence of a …
Moreover, TCIs are not associated with a decrease in immunocompetence in the skin and there is no increase in the incidence of infections wi …
Localized granulomatous reaction to a semi-permanent hyaluronic acid and acrylic hydrogel cosmetic filler.
Sidwell RU, Dhillon AP, Butler PE, Rustin MH. Sidwell RU, et al. Among authors: rustin mh. Clin Exp Dermatol. 2004 Nov;29(6):630-2. doi: 10.1111/j.1365-2230.2004.01625.x. Clin Exp Dermatol. 2004. PMID: 15550141
Dermalive, an injectable skin filler composed of a combination of synthetic hyaluronic acid and acrylic hydrogel particles was recently developed for soft tissue augmentation. Dermalive produces longer term results than temporary injectable fillers and is associated with a …
Dermalive, an injectable skin filler composed of a combination of synthetic hyaluronic acid and acrylic hydrogel particles was recently deve …
Lupus erythematosus vegetans.
Khorshid SM, Beynon HL, Rustin MH. Khorshid SM, et al. Among authors: rustin mh. Br J Dermatol. 1999 Nov;141(5):893-6. doi: 10.1046/j.1365-2133.1999.03164.x. Br J Dermatol. 1999. PMID: 10583174
Direct immunofluorescence studies revealed the presence of a definite basement membrane zone band for IgG, IgM and C3, favouring lupus erythematosus. We propose the term lupus erythematosus vegetans for this combination of clinicopathological and immunohistological finding …
Direct immunofluorescence studies revealed the presence of a definite basement membrane zone band for IgG, IgM and C3, favouring lupus eryth …
The treatment of chilblains with nifedipine: the results of a pilot study, a double-blind placebo-controlled randomized study and a long-term open trial.
Rustin MH, Newton JA, Smith NP, Dowd PM. Rustin MH, et al. Br J Dermatol. 1989 Feb;120(2):267-75. doi: 10.1111/j.1365-2133.1989.tb07792.x. Br J Dermatol. 1989. PMID: 2647123 Clinical Trial.
A pilot study, a double-blind placebo-controlled randomised study and a long term open trial have indicated that nifedipine is effective in the treatment of perniosis. ...
A pilot study, a double-blind placebo-controlled randomised study and a long term open trial have indicated that nifedipine is effect …
Ultrasound as a screening procedure for methotrexate-induced hepatic damage in severe psoriasis.
Miller JA, Dodd H, Rustin MH, Lees WR, Levene GM, Kirby JD, Munro DD. Miller JA, et al. Among authors: rustin mh. Br J Dermatol. 1985 Dec;113(6):699-705. doi: 10.1111/j.1365-2133.1985.tb02405.x. Br J Dermatol. 1985. PMID: 3913457
Methotrexate has been of proven value in the management of patients with severe psoriasis. Its long-term use, however, can be complicated by progressive hepatic damage which has necessitated regular liver biopsies. ...
Methotrexate has been of proven value in the management of patients with severe psoriasis. Its long-term use, however, can be complic …