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A role for β-catenin in diet-induced skeletal muscle insulin resistance.
Masson SWC, Dissanayake WC, Broome SC, Hedges CP, Peeters WM, Gram M, Rowlands DS, Shepherd PR, Merry TL. Masson SWC, et al. Among authors: rowlands ds. Physiol Rep. 2023 Feb;11(4):e15536. doi: 10.14814/phy2.15536. Physiol Rep. 2023. PMID: 36807886 Free PMC article.
Here, we investigate its role in skeletal muscle insulin resistance. Short-term (5-week) high-fat diet (HFD) decreased skeletal muscle beta-catenin protein expression 27% (p = 0.03), and perturbed insulin-stimulated beta-catenin(S552) phosphorylation 21% (p = 0.009) withou …
Here, we investigate its role in skeletal muscle insulin resistance. Short-term (5-week) high-fat diet (HFD) decreased skeletal muscl …
Thermal stabilization of enterovirus A 71 and production of antigenically stabilized empty capsids.
Kingston NJ, Shegdar M, Snowden JS, Fox H, Groppelli E, Macadam A, Rowlands DJ, Stonehouse NJ. Kingston NJ, et al. Among authors: rowlands dj. J Gen Virol. 2022 Aug;103(8):001771. doi: 10.1099/jgv.0.001771. J Gen Virol. 2022. PMID: 35997623 Free PMC article.
In the closely related poliovirus, native and expanded antigenic forms of particle have different long-term protective efficacies when used as vaccines. The native form provides long-lived protective immunity, while expanded capsids fail to generate immunological protectio …
In the closely related poliovirus, native and expanded antigenic forms of particle have different long-term protective efficacies whe …
Efficacy of Exercise Intervention for Weight Loss in Overweight and Obese Adolescents: Meta-Analysis and Implications.
Stoner L, Rowlands D, Morrison A, Credeur D, Hamlin M, Gaffney K, Lambrick D, Matheson A. Stoner L, et al. Among authors: rowlands d. Sports Med. 2016 Nov;46(11):1737-1751. doi: 10.1007/s40279-016-0537-6. Sports Med. 2016. PMID: 27139723 Review.
The effects of exercise on total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, fasting insulin and fasting blood glucose were inconclusive. LIMITATIONS: Most of the included trials were short term (6-36 weeks) and 13 had methodolog …
The effects of exercise on total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, fasting insulin and …
Long-term use of ticagrelor in patients with prior myocardial infarction.
Bonaca MP, Bhatt DL, Cohen M, Steg PG, Storey RF, Jensen EC, Magnani G, Bansilal S, Fish MP, Im K, Bengtsson O, Oude Ophuis T, Budaj A, Theroux P, Ruda M, Hamm C, Goto S, Spinar J, Nicolau JC, Kiss RG, Murphy SA, Wiviott SD, Held P, Braunwald E, Sabatine MS; PEGASUS-TIMI 54 Steering Committee and Investigators. Bonaca MP, et al. N Engl J Med. 2015 May 7;372(19):1791-800. doi: 10.1056/NEJMoa1500857. Epub 2015 Mar 14. N Engl J Med. 2015. PMID: 25773268 Free article. Clinical Trial.
Opportunities for improvement in anti-thrombotic therapy and other strategies for the management of acute coronary syndromes: Insights from EPICOR, an international study of current practice patterns.
Bueno H, Sinnaeve P, Annemans L, Danchin N, Licour M, Medina J, Pocock S, Sánchez-Covisa J, Storey RF, Jukema JW, Zeymer U, Van de Werf F; EPICOR Investigators. Bueno H, et al. Eur Heart J Acute Cardiovasc Care. 2016 Feb;5(1):3-12. doi: 10.1177/2048872614565912. Epub 2015 Jan 5. Eur Heart J Acute Cardiovasc Care. 2016. PMID: 25561688
AIMS: To describe international patterns and opportunities for improvement of pre- and in-hospital care of patients hospitalized for acute coronary syndromes (ACS), with special focus on anti-thrombotic therapy. METHODS AND RESULTS: EPICOR (long-tErm follow-uP of anti-thro …
AIMS: To describe international patterns and opportunities for improvement of pre- and in-hospital care of patients hospitalized for acute c …
High-protein, low-fat, short-term diet results in less stress and fatigue than moderate-protein moderate-fat diet during weight loss in male weightlifters: a pilot study.
Helms ER, Zinn C, Rowlands DS, Naidoo R, Cronin J. Helms ER, et al. Among authors: rowlands ds. Int J Sport Nutr Exerc Metab. 2015 Apr;25(2):163-70. doi: 10.1123/ijsnem.2014-0056. Epub 2014 Jul 14. Int J Sport Nutr Exerc Metab. 2015. PMID: 25028958 Clinical Trial.
CONCLUSIONS: For the 2 weeks observed, strength and anthropometric differences were minimal while stress, fatigue, and diet-dissatisfaction were higher during MPMF. A HPLF diet during short-term weight loss may be more effective at mitigating mood disturbance, fatigue, die …
CONCLUSIONS: For the 2 weeks observed, strength and anthropometric differences were minimal while stress, fatigue, and diet-dissatisfaction …
The effects of uniquely-processed titanium on biological systems: implications for human health and performance.
Rowlands DS, Shultz SP, Ogawa T, Aoi W, Korte M. Rowlands DS, et al. J Funct Biomater. 2014 Jan 3;5(1):1-14. doi: 10.3390/jfb5010001. J Funct Biomater. 2014. PMID: 24956353 Free PMC article.
In vitro studies have shown that application of Aqua Titan can modify membrane potential and long-term potentiation in isolated hippocampal neurons, suggesting reduced pain memory as a possible mechanism for reported analgesia. ...
In vitro studies have shown that application of Aqua Titan can modify membrane potential and long-term potentiation in isolated hippo …
Autologous blood injection to treat achilles tendinopathy? A randomized controlled trial.
Pearson J, Rowlands D, Highet R. Pearson J, et al. Among authors: rowlands d. J Sport Rehabil. 2012 Aug;21(3):218-24. doi: 10.1123/jsr.21.3.218. Epub 2011 Nov 16. J Sport Rehabil. 2012. PMID: 22104390 Clinical Trial.
Predictors of response to treatment were unremarkable, and a 21% rate of postinjection flare was the only noteworthy side effect. CONCLUSIONS: There is some evidence for small short-term symptomatic improvements with the addition of autologous blood injection to standard t …
Predictors of response to treatment were unremarkable, and a 21% rate of postinjection flare was the only noteworthy side effect. CONCLUSION …
Effects of homocysteine-lowering with folic acid plus vitamin B12 vs placebo on mortality and major morbidity in myocardial infarction survivors: a randomized trial.
Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH) Collaborative Group; Armitage JM, Bowman L, Clarke RJ, Wallendszus K, Bulbulia R, Rahimi K, Haynes R, Parish S, Sleight P, Peto R, Collins R. Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH) Collaborative Group, et al. JAMA. 2010 Jun 23;303(24):2486-94. doi: 10.1001/jama.2010.840. JAMA. 2010. PMID: 20571015 Clinical Trial.
Nor were there significant differences in the numbers of deaths attributed to vascular causes (vitamins, 578 [9.6%], vs placebo, 559 [9.3%]) or nonvascular causes (vitamins, 405 [6.7%], vs placebo, 392 [6.5%]) or in the incidence of any cancer (vitamins, 678 [11.2%], vs placebo, …
Nor were there significant differences in the numbers of deaths attributed to vascular causes (vitamins, 578 [9.6%], vs placebo, 559 [9.3%]) …
mRNA expression profiling of phyllodes tumours of the breast: identification of genes important in the development of borderline and malignant phyllodes tumours.
Jones AM, Mitter R, Poulsom R, Gillett C, Hanby AM, Tomlinson IP, Sawyer EJ; Phyllodes Tumour Consortium. Jones AM, et al. J Pathol. 2008 Dec;216(4):408-17. doi: 10.1002/path.2439. J Pathol. 2008. PMID: 18937276
The functional consequences of down-regulating these genes were studied using siRNA in short-term cultures and cell lines established from PTs. mRNA 'knock-down' of PAX3 resulted in significantly decreased cell proliferation in both a malignant and a borderline PT cell cul …
The functional consequences of down-regulating these genes were studied using siRNA in short-term cultures and cell lines established …
18 results