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Age and Aspirin Dosing in Secondary Prevention of Atherosclerotic Cardiovascular Disease.
Marquis-Gravel G, Stebbins A, Wruck LM, Roe MT, Effron MB, Hammill BG, Whittle J, VanWormer JJ, Robertson HR, Alikhaani JD, Kripalani S, Farrehi PM, Girotra S, Benziger CP, Polonsky TS, Merritt JG, Gupta K, McCormick TE 3rd, Knowlton KU, Jain SK, Kochar A, Rothman RL, Harrington RA, Hernandez AF, Jones WS. Marquis-Gravel G, et al. Among authors: rothman rl. J Am Heart Assoc. 2024 Feb 20;13(4):e026921. doi: 10.1161/JAHA.122.026921. Epub 2024 Feb 13. J Am Heart Assoc. 2024. PMID: 38348779 Free PMC article. Clinical Trial.
METHODS AND RESULTS: In the ADAPTABLE (Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-Term Effectiveness) trial, patients with atherosclerotic cardiovascular disease were randomized to daily aspirin doses of 81 mg or 325 mg. ...
METHODS AND RESULTS: In the ADAPTABLE (Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-Term Effectiveness) trial, …
Aspirin Dosing for Secondary Prevention of Atherosclerotic Cardiovascular Disease in Patients Treated With P2Y12 Inhibitors.
Girotra S, Stebbins A, Wruck L, Marquis-Gravel G, Gupta K, Farrehi P, Benziger CP, Effron MB, Whittle J, Muñoz D, Kripalani S, Anderson RD, Jain SK, Polonsky TS, Ahmad FS, Roe MT, Rothman RL, Harrington RA, Hernandez AF, Jones WS. Girotra S, et al. Among authors: rothman rl. J Am Heart Assoc. 2023 Oct 17;12(20):e030385. doi: 10.1161/JAHA.123.030385. Epub 2023 Oct 13. J Am Heart Assoc. 2023. PMID: 37830344 Free PMC article. Clinical Trial.
Background The ADAPTABLE (Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-Term Effectiveness) was a large, pragmatic, randomized controlled trial that found no difference between high- versus low-dose aspirin for secondary prevention of atherosclerotic …
Background The ADAPTABLE (Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-Term Effectiveness) was a large, pragma …
Effectiveness and Safety of Enteric-Coated vs Uncoated Aspirin in Patients With Cardiovascular Disease: A Secondary Analysis of the ADAPTABLE Randomized Clinical Trial.
Sleem A, Effron MB, Stebbins A, Wruck LM, Marquis-Gravel G, Muñoz D, Re RN, Gupta K, Pepine CJ, Jain SK, Girotra S, Whittle J, Benziger CP, Farrehi PM, Knowlton KU, Polonsky TS, Roe MT, Rothman RL, Harrington RA, Jones WS, Hernandez AF. Sleem A, et al. Among authors: rothman rl. JAMA Cardiol. 2023 Nov 1;8(11):1061-1069. doi: 10.1001/jamacardio.2023.3364. JAMA Cardiol. 2023. PMID: 37792369 Free PMC article. Clinical Trial.
DESIGN, SETTING, AND PARTICIPANTS: This is a post hoc secondary analysis of ADAPTABLE (Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-term Effectiveness), a pragmatic study of 15 076 patients with atherosclerotic cardiovascular disease having data in t …
DESIGN, SETTING, AND PARTICIPANTS: This is a post hoc secondary analysis of ADAPTABLE (Aspirin Dosing: A Patient-Centric Trial Assessing Ben …
Internet Versus Noninternet Participation in a Decentralized Clinical Trial: Lessons From the ADAPTABLE Study.
Shen R, Mulder H, Wruck L, Weissler EH, Robertson HR, Sharlow AG, Kripalani S, Muñoz D, Effron MB, Gupta K, Girotra S, Whittle J, Benziger CP, VanWormer JJ, Polonsky TS, Rothman RL, Harrington RA, Hernandez AF, Jones WS. Shen R, et al. Among authors: rothman rl. J Am Heart Assoc. 2023 Jul 4;12(13):e027899. doi: 10.1161/JAHA.122.027899. Epub 2023 Jun 22. J Am Heart Assoc. 2023. PMID: 37345815 Free PMC article. Clinical Trial.
Methods and Results In a subanalysis of the ADAPTABLE (Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-Term Effectiveness) study, we compared internet participants with those who opted for noninternet participation. ...
Methods and Results In a subanalysis of the ADAPTABLE (Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-Term Effec …
The Greenlight Plus Trial: Comparative effectiveness of a health information technology intervention vs. health communication intervention in primary care offices to prevent childhood obesity.
Heerman WJ, Perrin EM, Yin HS, Schildcrout JS, Delamater AM, Flower KB, Sanders L, Wood C, Kay MC, Adams LE, Rothman RL. Heerman WJ, et al. Among authors: rothman rl. Contemp Clin Trials. 2022 Dec;123:106987. doi: 10.1016/j.cct.2022.106987. Epub 2022 Oct 30. Contemp Clin Trials. 2022. PMID: 36323344 Clinical Trial.
BACKGROUND: The first 1000 days of a child's life are increasingly recognized as a critical window for establishing a healthy growth trajectory to prevent childhood obesity and its associated long-term comorbidities. The purpose of this manuscript is to detail the methods …
BACKGROUND: The first 1000 days of a child's life are increasingly recognized as a critical window for establishing a healthy growth traject …
Feasibility and Short-Term Effects of a Multi-Component Emergency Department Blood Pressure Intervention: A Pilot Randomized Trial.
Spieker AJ, Nelson LA, Rothman RL, Roumie CL, Kripalani S, Coco J, Fabbri D, Levy P, Collins SP, Wang T, Liu D, McNaughton CD. Spieker AJ, et al. Among authors: rothman rl. J Am Heart Assoc. 2022 Mar;11(5):e024339. doi: 10.1161/JAHA.121.024339. Epub 2022 Feb 23. J Am Heart Assoc. 2022. PMID: 35195015 Free PMC article. Clinical Trial.
Background Emergency department (ED) visits can be opportunities to address uncontrolled hypertension. We sought to compare short-term blood pressure measures between the Vanderbilt Emergency Room Bundle (VERB) intervention and usual care plus education. ...
Background Emergency department (ED) visits can be opportunities to address uncontrolled hypertension. We sought to compare short-term …
A Health-Literacy Intervention for Early Childhood Obesity Prevention: A Cluster-Randomized Controlled Trial.
Sanders LM, Perrin EM, Yin HS, Delamater AM, Flower KB, Bian A, Schildcrout JS, Rothman RL; Greenlight Study Team. Sanders LM, et al. Among authors: rothman rl. Pediatrics. 2021 May;147(5):e2020049866. doi: 10.1542/peds.2020-049866. Pediatrics. 2021. PMID: 33911032 Free PMC article. Clinical Trial.
BACKGROUND AND OBJECTIVES: Children who become overweight by age 2 have greater risk of long-term obesity and health problems. The study aim was to assess the effectiveness of a primary care-based intervention on the prevalence of overweight at age 24 months. ...Inclusion …
BACKGROUND AND OBJECTIVES: Children who become overweight by age 2 have greater risk of long-term obesity and health problems. The st …
Parental Feeding Beliefs and Practices and Household Food Insecurity in Infancy.
Orr CJ, Ben-Davies M, Ravanbakht SN, Yin HS, Sanders LM, Rothman RL, Delamater AM, Wood CT, Perrin EM. Orr CJ, et al. Among authors: rothman rl. Acad Pediatr. 2019 Jan-Feb;19(1):80-89. doi: 10.1016/j.acap.2018.09.007. Epub 2018 Sep 21. Acad Pediatr. 2019. PMID: 30248471 Free PMC article.
Differences in caregiver feeding practices by food security status and race/ethnicity were explored with an interaction term (food security status x race/ethnicity). RESULTS: Forty-three percent of families screened as food insecure. ...
Differences in caregiver feeding practices by food security status and race/ethnicity were explored with an interaction term (food se …
The Changing Landscape of Randomized Clinical Trials in Cardiovascular Disease.
Jones WS, Roe MT, Antman EM, Pletcher MJ, Harrington RA, Rothman RL, Oetgen WJ, Rao SV, Krucoff MW, Curtis LH, Hernandez AF, Masoudi FA. Jones WS, et al. Among authors: rothman rl. J Am Coll Cardiol. 2016 Oct 25;68(17):1898-1907. doi: 10.1016/j.jacc.2016.07.781. J Am Coll Cardiol. 2016. PMID: 27765193 Free article. Review.
This review will examine the current landscape of cardiovascular clinical trials in the United States, highlight recently conducted registry-based clinical trials, and discuss the potential attributes of the recently launched pragmatic clinical trial by the Patient-Centered Outco …
This review will examine the current landscape of cardiovascular clinical trials in the United States, highlight recently conducted registry …
Association Between Bottle Size and Formula Intake in 2-Month-Old Infants.
Wood CT, Skinner AC, Yin HS, Rothman RL, Sanders LM, Delamater A, Ravanbakht SN, Perrin EM. Wood CT, et al. Among authors: rothman rl. Acad Pediatr. 2016 Apr;16(3):254-9. doi: 10.1016/j.acap.2015.08.001. Epub 2015 Sep 26. Acad Pediatr. 2016. PMID: 26525989 Free PMC article.
METHODS: Cross-sectional analysis of baseline data collected as part of Greenlight, a cluster randomized trial to prevent childhood obesity at 4 pediatric resident clinics. The Greenlight study included healthy, term infants. For our analysis, parents of exclusively formul …
METHODS: Cross-sectional analysis of baseline data collected as part of Greenlight, a cluster randomized trial to prevent childhood obesity …
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