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[Medical follow-up after organ transplantation].
Rostaing L. Rostaing L. Rev Prat. 2023 Nov;73(9):976-979. Rev Prat. 2023. PMID: 38294447 French.
The role of the general practitioner is essential in the follow-up of solid organ transplant patients, both in the first year and over the long term, particularly beyond the first year, in relation to the organ transplant specialist. ...
The role of the general practitioner is essential in the follow-up of solid organ transplant patients, both in the first year and over the l …
Idiopathic Nephrotic Syndrome in Children in Chad: Epidemiology and Clinical Outcomes.
Mahamat Abderraman G, Djidita Hagré Y, Mahamat HA, Charfadine S, Amne AS, Khadidja AA, Rostaing L. Mahamat Abderraman G, et al. Among authors: rostaing l. J Clin Med. 2023 Dec 11;12(24):7626. doi: 10.3390/jcm12247626. J Clin Med. 2023. PMID: 38137694 Free PMC article.
None of the patients with idiopathic NS died. At the last follow-up, sixteen patients (80%) achieved long-term complete remission with normal renal function; however, four of those had subsequent relapses. ...CONCLUSION: In Chad, childhood idiopathic nephrotic syndrome pre …
None of the patients with idiopathic NS died. At the last follow-up, sixteen patients (80%) achieved long-term complete remission wit …
[Improving access to kidney transplantation for highly sensitized patients: What place for IL-6 pathway blockade in desensitization protocols?].
Weinhard J, Noble J, Jouve T, Malvezzi P, Rostaing L. Weinhard J, et al. Among authors: rostaing l. Nephrol Ther. 2022 Dec;18(7):577-583. doi: 10.1016/j.nephro.2022.07.402. Epub 2022 Oct 31. Nephrol Ther. 2022. PMID: 36328901 French.
However, lymphocyte immunophenotyping showed that tocilizumab hindered B cells maturation. Thereby, tocilizumab could improve long-term efficacy of desensitization, by limiting the anti-HLA rebound and so avoiding antibody-mediated rejection. ...In association with standar …
However, lymphocyte immunophenotyping showed that tocilizumab hindered B cells maturation. Thereby, tocilizumab could improve long-term …
Redefining Risk Stratification and Endpoints for Clinical Trials in Kidney Transplantation: Rationale and Methodology of Proposals Submitted to the European Medicines Agency by the European Society for Organ Transplantation.
Naesens M, Schneeberger S; ESOT Working Group. Naesens M, et al. Transpl Int. 2022 May 20;35:10142. doi: 10.3389/ti.2021.10142. eCollection 2022. Transpl Int. 2022. PMID: 35992750 Free PMC article.
The European Society for Organ Transplantation (ESOT) submitted a Broad Scientific Advice request to the European Medicines Agency (EMA) in 2018, to explore whether updating guidelines on clinical trial endpoints would encourage innovations in kidney transplantation research, the …
The European Society for Organ Transplantation (ESOT) submitted a Broad Scientific Advice request to the European Medicines Agency (EMA) in …
Tocilizumab and Active Antibody-Mediated Rejection in Kidney Transplantation: A Literature Review.
Cabezas L, Jouve T, Malvezzi P, Janbon B, Giovannini D, Rostaing L, Noble J. Cabezas L, et al. Among authors: rostaing l. Front Immunol. 2022 Apr 14;13:839380. doi: 10.3389/fimmu.2022.839380. eCollection 2022. Front Immunol. 2022. PMID: 35493469 Free PMC article. Review.
Antibody-mediated rejection (ABMR) is a significant complication following kidney transplantation: it contributes to both short- and long-term injury. The standard-of-care (SOC) therapy combines plasmapheresis and Intravenous Immunoglobulins (IVIg) with or without steroids …
Antibody-mediated rejection (ABMR) is a significant complication following kidney transplantation: it contributes to both short- and long- …
Conversion from Calcineurin Inhibitor- to Belatacept-Based Maintenance Immunosuppression in Renal Transplant Recipients: A Randomized Phase 3b Trial.
Budde K, Prashar R, Haller H, Rial MC, Kamar N, Agarwal A, de Fijter JW, Rostaing L, Berger SP, Djamali A, Leca N, Allamassey L, Gao S, Polinsky M, Vincenti F. Budde K, et al. Among authors: rostaing l. J Am Soc Nephrol. 2021 Dec 1;32(12):3252-3264. doi: 10.1681/ASN.2021050628. Epub 2021 Dec 1. J Am Soc Nephrol. 2021. PMID: 34706967 Free PMC article. Clinical Trial.
BACKGROUND: Calcineurin inhibitors (CNIs) are standard of care after kidney transplantation, but they are associated with nephrotoxicity and reduced long-term graft survival. Belatacept, a selective T cell costimulation blocker, is approved for the prophylaxis of kidney tr …
BACKGROUND: Calcineurin inhibitors (CNIs) are standard of care after kidney transplantation, but they are associated with nephrotoxicity and …
Tocilizumab and Desensitization in Kidney Transplant Candidates: Personal Experience and Literature Review.
Weinhard J, Noble J, Jouve T, Malvezzi P, Rostaing L. Weinhard J, et al. Among authors: rostaing l. J Clin Med. 2021 Sep 24;10(19):4359. doi: 10.3390/jcm10194359. J Clin Med. 2021. PMID: 34640377 Free PMC article. Review.
However, lymphocyte immuno-phenotyping has shown that TCZ hinders B-cell maturation and thus could improve the long-term efficacy of DES by limiting anti-HLA rebound and so avoid antibody-mediated rejection. ...In association with an SP, tocilizumab does not seem to signif …
However, lymphocyte immuno-phenotyping has shown that TCZ hinders B-cell maturation and thus could improve the long-term efficacy of …
A Case of Pneumocystis jirovecii Pneumonia under Belatacept and Everolimus: Benefit-Risk Balance between Renal Allograft Function and Infection.
Perrier Q, Portais A, Terrec F, Cerba Y, Romanet T, Malvezzi P, Bedouch P, Tetaz R, Rostaing L. Perrier Q, et al. Among authors: rostaing l. Case Rep Nephrol Dial. 2021 Jan 27;11(1):10-15. doi: 10.1159/000510842. eCollection 2021 Jan-Apr. Case Rep Nephrol Dial. 2021. PMID: 33708795 Free PMC article.
P. jirovecii pneumonia prophylaxis for the next 6 months was monthly aerosol of pentamidine. Long-term safety studies or early/late conversion to belatacept did not report on P. jirovecii pneumonia. ...
P. jirovecii pneumonia prophylaxis for the next 6 months was monthly aerosol of pentamidine. Long-term safety studies or early/late c …
Treatment of refractory myasthenia gravis by double-filtration plasmapheresis and rituximab: A case series of nine patients and literature review.
Bennani HN, Lagrange E, Noble J, Malvezzi P, Motte L, Chevallier E, Rostaing L, Jouve T. Bennani HN, et al. Among authors: rostaing l. J Clin Apher. 2021 Jun;36(3):348-363. doi: 10.1002/jca.21868. Epub 2020 Dec 21. J Clin Apher. 2021. PMID: 33349954 Review.
Clinical improvement assessed by MGFA score was sustained in the long-term for all patients, during an average follow-up of 14 9 months, allowing them to be self-sufficient and out sick-leave. ...
Clinical improvement assessed by MGFA score was sustained in the long-term for all patients, during an average follow-up of 14 9 mont …
Isoagglutinin removal by plasma centrifugation or filtration (single or double): A prospective study in a single center.
Naciri Bennani H, Noble J, Chevallier E, Terrec F, Motte L, Giroux-Lathuile C, Bugnazet M, Imerzoukene F, Janbon B, Malvezzi P, Rostaing L, Jouve T. Naciri Bennani H, et al. Among authors: rostaing l. J Clin Apher. 2021 Feb;36(1):149-160. doi: 10.1002/jca.21857. Epub 2020 Nov 23. J Clin Apher. 2021. PMID: 33230824
INTRODUCTION: ABO-incompatible (ABOi) kidney transplantation, a well-established procedure, has good long-term results provided pretransplant desensitization that includes immunosuppression and apheresis. ...
INTRODUCTION: ABO-incompatible (ABOi) kidney transplantation, a well-established procedure, has good long-term results provided pretr …
98 results