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Antiviral Activity of Oligonucleotides Targeting the SARS-CoV-2 Genomic RNA Stem-Loop Sequences within the 3'-End of the ORF1b.
Stincarelli MA, Rocca A, Antonelli A, Rossolini GM, Giannecchini S. Stincarelli MA, et al. Among authors: rossolini gm. Pathogens. 2022 Nov 1;11(11):1286. doi: 10.3390/pathogens11111286. Pathogens. 2022. PMID: 36365037 Free PMC article.
Increased evidence shows vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited no long-term efficacy and limited worldwide availability, while existing antivirals and treatment options have only limited efficacy. ...
Increased evidence shows vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited no long-term efficac …
Long-term SARS-CoV-2 Asymptomatic Carriage in an Immunocompromised Host: Clinical, Immunological, and Virological Implications.
Spinicci M, Mazzoni A, Coppi M, Antonelli A, Salvati L, Maggi L, Basile G, Graziani L, Di Lauria N, Di Pilato V, Kiros ST, Beccastrini E, Saccardi R, Angileri M, Cecchi M, Cusi MG, Rossolini GM, Annunziato F, Bartoloni A, Parronchi P. Spinicci M, et al. Among authors: rossolini gm. J Clin Immunol. 2022 Oct;42(7):1371-1378. doi: 10.1007/s10875-022-01313-6. Epub 2022 Jul 2. J Clin Immunol. 2022. PMID: 35779200 Free PMC article.
We describe the clinical, immunological, and virological course of a patient with eosinophilic granulomatosis with polyangiitis, who developed the status of long-term asymptomatic SARS-CoV-2 carrier for more than 7 months. METHODS: Over the study period, the patient underw …
We describe the clinical, immunological, and virological course of a patient with eosinophilic granulomatosis with polyangiitis, who develop …
SARS-CoV-2 infection and vaccination trigger long-lived B and CD4+ T lymphocytes with implications for booster strategies.
Mazzoni A, Vanni A, Spinicci M, Lamacchia G, Kiros ST, Rocca A, Capone M, Di Lauria N, Salvati L, Carnasciali A, Mantengoli E, Farahvachi P, Zammarchi L, Lagi F, Colao MG, Liotta F, Cosmi L, Maggi L, Bartoloni A, Rossolini GM, Annunziato F. Mazzoni A, et al. Among authors: rossolini gm. J Clin Invest. 2022 Mar 15;132(6):e157990. doi: 10.1172/JCI157990. J Clin Invest. 2022. PMID: 35139036 Free PMC article.
Finally, we observed a similar kinetics of decay of humoral and cellular immunity to SARS-CoV-2 up to 1 year following natural infection in a cohort of unvaccinated individuals.CONCLUSIONShort-term persistence of humoral immunity, together with the reduced neutralization c …
Finally, we observed a similar kinetics of decay of humoral and cellular immunity to SARS-CoV-2 up to 1 year following natural infection in …
Heterogeneous magnitude of immunological memory to SARS-CoV-2 in recovered individuals.
Mazzoni A, Maggi L, Capone M, Vanni A, Spinicci M, Salvati L, Tekle Kiros S, Semeraro R, Pengue L, Colao MG, Magi A, Rossolini GM, Liotta F, Cosmi L, Bartoloni A, Annunziato F. Mazzoni A, et al. Among authors: rossolini gm. Clin Transl Immunology. 2021 May 6;10(5):e1281. doi: 10.1002/cti2.1281. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33976879 Free PMC article.
In this work, we aimed to assess the maintenance of immunological memory to SARS-CoV-2. METHODS: We evaluated the long-term virus-specific cellular and humoral immune response in the members of an Italian Serie A football team, who experienced a cluster of COVID-19 in Marc …
In this work, we aimed to assess the maintenance of immunological memory to SARS-CoV-2. METHODS: We evaluated the long-term virus-spe …
Key considerations on the potential impacts of the COVID-19 pandemic on antimicrobial resistance research and surveillance.
Rodríguez-Baño J, Rossolini GM, Schultsz C, Tacconelli E, Murthy S, Ohmagari N, Holmes A, Bachmann T, Goossens H, Canton R, Roberts AP, Henriques-Normark B, Clancy CJ, Huttner B, Fagerstedt P, Lahiri S, Kaushic C, Hoffman SJ, Warren M, Zoubiane G, Essack S, Laxminarayan R, Plant L. Rodríguez-Baño J, et al. Among authors: rossolini gm. Trans R Soc Trop Med Hyg. 2021 Oct 1;115(10):1122-1129. doi: 10.1093/trstmh/trab048. Trans R Soc Trop Med Hyg. 2021. PMID: 33772597 Free PMC article.
These include the need to implement diagnostic stewardship to assess the global incidence of coinfections and secondary infections in COVID-19 patients, including those by multidrug-resistant pathogens, to identify patients most likely to benefit from antibiotic treatment and ide …
These include the need to implement diagnostic stewardship to assess the global incidence of coinfections and secondary infections in COVID- …
Antimicrobial resistance research in a post-pandemic world: Insights on antimicrobial resistance research in the COVID-19 pandemic.
Rodríguez-Baño J, Rossolini GM, Schultsz C, Tacconelli E, Murthy S, Ohmagari N, Holmes A, Bachmann T, Goossens H, Canton R, Roberts AP, Henriques-Normark B, Clancy CJ, Huttner B, Fagerstedt P, Lahiri S, Kaushic C, Hoffman SJ, Warren M, Zoubiane G, Essack S, Laxminarayan R, Plant L. Rodríguez-Baño J, et al. Among authors: rossolini gm. J Glob Antimicrob Resist. 2021 Jun;25:5-7. doi: 10.1016/j.jgar.2021.02.013. Epub 2021 Mar 1. J Glob Antimicrob Resist. 2021. PMID: 33662647 Free PMC article.
Harnessing the public understanding of the relevance of infectious diseases towards the long-term pandemic of AMR could have major implications for promoting good practices about the control of AMR transmission....
Harnessing the public understanding of the relevance of infectious diseases towards the long-term pandemic of AMR could have major im …
Population structure of KPC carbapenemase-producing Klebsiella pneumoniae in a long-term acute-care rehabilitation facility: identification of a new lineage of clonal group 101, associated with local hyperendemicity.
Arena F, Di Pilato V, Vannetti F, Fabbri L, Antonelli A, Coppi M, Pupillo R, Macchi C, Rossolini GM. Arena F, et al. Among authors: rossolini gm. Microb Genom. 2020 Jan;6(1):e000308. doi: 10.1099/mgen.0.000308. Microb Genom. 2020. PMID: 32003322 Free PMC article.
In this work, we used a whole-genome sequencing (WGS) approach to study the features of KPC-producing Klebsiella pneumoniae (KPC-Kp) spreading in a large Italian long-term acute-care rehabilitation facility (LTACRF), and to track the dynamics of dissemination within this s …
In this work, we used a whole-genome sequencing (WGS) approach to study the features of KPC-producing Klebsiella pneumoniae (KPC-Kp) spreadi …
In vitro time-kill kinetics of dalbavancin against Staphylococcus spp. biofilms over prolonged exposure times.
Di Pilato V, Ceccherini F, Sennati S, D'Agostino F, Arena F, D'Atanasio N, Di Giorgio FP, Tongiani S, Pallecchi L, Rossolini GM. Di Pilato V, et al. Among authors: rossolini gm. Diagn Microbiol Infect Dis. 2020 Feb;96(2):114901. doi: 10.1016/j.diagmicrobio.2019.114901. Epub 2019 Oct 15. Diagn Microbiol Infect Dis. 2020. PMID: 31761480 Free article.
Staphylococcus aureus and Staphylococcus epidermidis are leading pathogens of biofilm-related infections and represent the most common cause of osteomyelitis and biomedical implants infections. Biofilm-related infections usually require long-term antibiotic treatment, ofte …
Staphylococcus aureus and Staphylococcus epidermidis are leading pathogens of biofilm-related infections and represent the most common cause …
Influence of a 3-month low-calorie Mediterranean diet compared to the vegetarian diet on human gut microbiota and SCFA: the CARDIVEG Study.
Pagliai G, Russo E, Niccolai E, Dinu M, Di Pilato V, Magrini A, Bartolucci G, Baldi S, Menicatti M, Giusti B, Marcucci R, Rossolini GM, Casini A, Sofi F, Amedei A. Pagliai G, et al. Among authors: rossolini gm. Eur J Nutr. 2020 Aug;59(5):2011-2024. doi: 10.1007/s00394-019-02050-0. Epub 2019 Jul 10. Eur J Nutr. 2020. PMID: 31292752 Clinical Trial.
Finally, correlation analyses showed a potential relationship-modulated by the two diets-between changes of genera and changes of clinical and biochemical parameters. CONCLUSIONS: A short-term dietary intervention with MD or VD does not induce major change in the GM, sugge …
Finally, correlation analyses showed a potential relationship-modulated by the two diets-between changes of genera and changes of clinical a …
Role of place of acquisition and inappropriate empirical antibiotic therapy on the outcome of extended-spectrum β-lactamase-producing Enterobacteriaceae infections.
Tacconelli E, Cataldo MA, Mutters NT, Carrara E, Bartoloni A, Raglio A, Cauda R, Mantengoli E, Luzzaro F, Pan A, Beccara LA, Pecile P, Tinelli M, Rossolini GM. Tacconelli E, et al. Among authors: rossolini gm. Int J Antimicrob Agents. 2019 Jul;54(1):49-54. doi: 10.1016/j.ijantimicag.2019.04.007. Epub 2019 Apr 12. Int J Antimicrob Agents. 2019. PMID: 30986523
14 results