Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

13 results

Filters applied: . Clear all
Page 1
The Sweet Pee model for Sglt2 mutation.
Ly JP, Onay T, Sison K, Sivaskandarajah G, Sabbisetti V, Li L, Bonventre JV, Flenniken A, Paragas N, Barasch JM, Adamson SL, Osborne L, Rossant J, Schnermann J, Quaggin SE. Ly JP, et al. Among authors: rossant j. J Am Soc Nephrol. 2011 Jan;22(1):113-23. doi: 10.1681/ASN.2010080888. J Am Soc Nephrol. 2011. PMID: 21209254 Free PMC article.
An animal model with sglt2 dysfunction could provide information regarding the potential long-term safety and efficacy of SGLT2 inhibitors, which are currently under clinical investigation. ...After induction of diabetes, Sweet Pee mice had better overall glycemic control …
An animal model with sglt2 dysfunction could provide information regarding the potential long-term safety and efficacy of SGLT2 inhib …
Comparative systems biology of human and mouse as a tool to guide the modeling of human placental pathology.
Cox B, Kotlyar M, Evangelou AI, Ignatchenko V, Ignatchenko A, Whiteley K, Jurisica I, Adamson SL, Rossant J, Kislinger T. Cox B, et al. Among authors: rossant j. Mol Syst Biol. 2009;5:279. doi: 10.1038/msb.2009.37. Epub 2009 Jun 16. Mol Syst Biol. 2009. PMID: 19536202 Free PMC article.
We collected protein and mRNA expression data through shot-gun proteomics and microarray expression analysis of the highly vascular exchange region, microdissected from the human and mouse near-term placenta. Over 7000 ortholog genes were detected with 70% co-expressed in …
We collected protein and mRNA expression data through shot-gun proteomics and microarray expression analysis of the highly vascular exchange …
Trophoblast-specific gene manipulation using lentivirus-based vectors.
Georgiades P, Cox B, Gertsenstein M, Chawengsaksophak K, Rossant J. Georgiades P, et al. Among authors: rossant j. Biotechniques. 2007 Mar;42(3):317-8, 320, 322-5. doi: 10.2144/000112341. Biotechniques. 2007. PMID: 17390538 Free article.
Development of tools to specifically and efficiently manipulate gene expression in the trophoblast lineage would greatly aid understanding of the relative roles of different genetic pathways in the trophoblast versus embryonic lineages. We show that short-term lentivirus-m …
Development of tools to specifically and efficiently manipulate gene expression in the trophoblast lineage would greatly aid understanding o …
High resolution ultrasound-guided microinjection for interventional studies of early embryonic and placental development in vivo in mice.
Slevin JC, Byers L, Gertsenstein M, Qu D, Mu J, Sunn N, Kingdom JC, Rossant J, Adamson SL. Slevin JC, et al. Among authors: rossant j. BMC Dev Biol. 2006 Feb 27;6:10. doi: 10.1186/1471-213X-6-10. BMC Dev Biol. 2006. PMID: 16504164 Free PMC article.
Seventy eight percent of the embryos survived 2 to 12 days post injection (93/119), 73% (41/56) survived to term of which 68% (38/56) survived and appeared normal one week after birth. ...At E11.5, beads microinjected at E7.5 into the ectoplacental cone region were …
Seventy eight percent of the embryos survived 2 to 12 days post injection (93/119), 73% (41/56) survived to term of which 68% (38/56) …
Genetic regulation of stem cell origins in the mouse embryo.
Ralston A, Rossant J. Ralston A, et al. Among authors: rossant j. Clin Genet. 2005 Aug;68(2):106-12. doi: 10.1111/j.1399-0004.2005.00478.x. Clin Genet. 2005. PMID: 15996204 Review.
'Stem cell' has practically become a household term, but what is a stem cell and where does it come from? Insight into these questions has come from the early mouse embryo, or blastocyst, from which three kinds of stem cells have been derived: embryonic stem (ES) cells, tr …
'Stem cell' has practically become a household term, but what is a stem cell and where does it come from? Insight into these question …
A novel in vitro model of trophoblast-mediated decidual blood vessel remodeling.
Dunk C, Petkovic L, Baczyk D, Rossant J, Winterhager E, Lye S. Dunk C, et al. Among authors: rossant j. Lab Invest. 2003 Dec;83(12):1821-8. doi: 10.1097/01.lab.0000101730.69754.5a. Lab Invest. 2003. PMID: 14691300 Free article.
In vivo the extravillous trophoblasts (EVTs) penetrate the decidua and the first third of the myometrium to remodel the uterine spiral arteries and achieve the high-flow, low-resistance circulation characteristic of the intervillous space of the term placenta. Much of our …
In vivo the extravillous trophoblasts (EVTs) penetrate the decidua and the first third of the myometrium to remodel the uterine spiral arter …
Cardiac malformation in neonatal mice lacking connexin43.
Reaume AG, de Sousa PA, Kulkarni S, Langille BL, Zhu D, Davies TC, Juneja SC, Kidder GM, Rossant J. Reaume AG, et al. Among authors: rossant j. Science. 1995 Mar 24;267(5205):1831-4. doi: 10.1126/science.7892609. Science. 1995. PMID: 7892609
Targeted mutagenesis of connexin43 (Cx43), one of the most prevalent connexin proteins, showed that its absence was compatible with survival of mouse embryos to term, even though mutant cell lines showed reduced dye coupling in vitro. However, mutant embryos died at bir …
Targeted mutagenesis of connexin43 (Cx43), one of the most prevalent connexin proteins, showed that its absence was compatible with survival …
Long-term reconstitution of the mouse hematopoietic system by embryonic stem cell-derived fetal liver.
Forrester LM, Bernstein A, Rossant J, Nagy A. Forrester LM, et al. Among authors: rossant j. Proc Natl Acad Sci U S A. 1991 Sep 1;88(17):7514-7. doi: 10.1073/pnas.88.17.7514. Proc Natl Acad Sci U S A. 1991. PMID: 1881890 Free PMC article.
ES cell-derived hematopoietic stem cells were capable of long-term (greater than 6 months) repopulation of irradiated recipients, and all hematopoietic cell lineages analyzed (erythrocytes, T cells, mast cells, and macrophages) were derived exclusively from ES cells in suc …
ES cell-derived hematopoietic stem cells were capable of long-term (greater than 6 months) repopulation of irradiated recipients, and …
Inducible expression of an hsp68-lacZ hybrid gene in transgenic mice.
Kothary R, Clapoff S, Darling S, Perry MD, Moran LA, Rossant J. Kothary R, et al. Among authors: rossant j. Development. 1989 Apr;105(4):707-14. doi: 10.1242/dev.105.4.707. Development. 1989. PMID: 2557196
This tightly regulated inducible promoter may provide a useful tool for short-term inducible gene expression in transgenic mice....
This tightly regulated inducible promoter may provide a useful tool for short-term inducible gene expression in transgenic mice....
Interspecific hybrids and chimeras in mice.
Rossant J, Croy BA, Clark DA, Chapman VM. Rossant J, et al. J Exp Zool. 1983 Nov;228(2):223-33. doi: 10.1002/jez.1402280208. J Exp Zool. 1983. PMID: 6663258
It is clear, however, that it is the trophoblast layer that mediates survival or death of the foreign embryonic cells in the M. musculus juterus, since M. caroli inner cell mass cells can survive to term after injection into M. musculus blastocysts: Viable interspecific ch …
It is clear, however, that it is the trophoblast layer that mediates survival or death of the foreign embryonic cells in the M. musculus jut …
13 results