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Short-term exposure to a clinical dose of metformin increases skeletal muscle mitochondrial H(2)O(2) emission and production in healthy, older adults: A randomized controlled trial.
McKenzie AI, Mahmassani ZS, Petrocelli JJ, de Hart NMMP, Fix DK, Ferrara PJ, LaStayo PC, Marcus RL, Rondina MT, Summers SA, Johnson JM, Trinity JD, Funai K, Drummond MJ. McKenzie AI, et al. Among authors: rondina mt. Exp Gerontol. 2022 Jun 15;163:111804. doi: 10.1016/j.exger.2022.111804. Epub 2022 Apr 9. Exp Gerontol. 2022. PMID: 35405248 Free PMC article. Clinical Trial.
Emerging evidence suggests that metformin could have off target effects that might help promote healthy muscle aging, but these effects have not been thoroughly studied in glucose tolerant older individuals. The purpose of this study was to investigate the short-term effec …
Emerging evidence suggests that metformin could have off target effects that might help promote healthy muscle aging, but these effects have …
Impact of presymptomatic COVID-19 on vascular and skeletal muscle function: a case study.
Trinity JD, Craig JC, Fermoyle CC, McKenzie AI, Lewis MT, Park SH, Rondina MT, Richardson RS. Trinity JD, et al. Among authors: rondina mt. J Appl Physiol (1985). 2021 Jun 1;130(6):1961-1970. doi: 10.1152/japplphysiol.00236.2021. Epub 2021 May 18. J Appl Physiol (1985). 2021. PMID: 34002634 Free PMC article.
This integrative case study indicates that the presymptomatic impact of COVID-19 is widespread and may help elucidate the acute and long-term sequelae of this disease....
This integrative case study indicates that the presymptomatic impact of COVID-19 is widespread and may help elucidate the acute and long- …
Inflammatory, synaptic, motor, and behavioral alterations induced by gestational sepsis on the offspring at different stages of life.
Granja MG, Alves LP, Leardini-Tristão M, Saul ME, Bortoni LC, de Moraes FM, Ferreira EC, de Moraes BPT, da Silva VZ, Dos Santos AFR, Silva AR, Gonçalves-de-Albuquerque CF, Bambini-Junior V, Weyrich AS, Rondina MT, Zimmerman GA, de Castro-Faria-Neto HC. Granja MG, et al. Among authors: rondina mt. J Neuroinflammation. 2021 Feb 25;18(1):60. doi: 10.1186/s12974-021-02106-1. J Neuroinflammation. 2021. PMID: 33632243 Free PMC article.
BACKGROUND: The term sepsis is used to designate a systemic condition of infection and inflammation associated with hemodynamic changes that result in organic dysfunction. ...
BACKGROUND: The term sepsis is used to designate a systemic condition of infection and inflammation associated with hemodynamic chang …
Quality of life after pharmacomechanical catheter-directed thrombolysis for proximal deep venous thrombosis.
Kahn SR, Julian JA, Kearon C, Gu CS, Cohen DJ, Magnuson EA, Comerota AJ, Goldhaber SZ, Jaff MR, Razavi MK, Kindzelski AL, Schneider JR, Kim P, Chaer R, Sista AK, McLafferty RB, Kaufman JA, Wible BC, Blinder M, Vedantham S; ATTRACT Trial Investigators. Kahn SR, et al. J Vasc Surg Venous Lymphat Disord. 2020 Jan;8(1):8-23.e18. doi: 10.1016/j.jvsv.2019.03.023. J Vasc Surg Venous Lymphat Disord. 2020. PMID: 31843251 Free PMC article. Clinical Trial.
We aimed to assess whether pharmacomechanical catheter-directed thrombolysis (PCDT) improves short-term or long-term QOL in patients with proximal DVT and whether QOL is related to extent of DVT. ...
We aimed to assess whether pharmacomechanical catheter-directed thrombolysis (PCDT) improves short-term or long-term QOL in pa …
Blood donor-derived buffy coat to produce platelets in vitro.
Marini I, Rigoni F, Zlamal J, Pelzl L, Althaus K, Nowak-Harnau S, Rondina MT, Bakchoul T. Marini I, et al. Among authors: rondina mt. Vox Sang. 2020 Jan;115(1):94-102. doi: 10.1111/vox.12863. Epub 2019 Nov 10. Vox Sang. 2020. PMID: 31709567
The number and the quality of magnetically isolated CD34+ cells and their capability to differentiate into mature megakaryocytes were investigated using flow cytometry. Additionally, the functionality of megakaryocytes in term of in vitro platelet production was tested. RE …
The number and the quality of magnetically isolated CD34+ cells and their capability to differentiate into mature megakaryocytes were invest …
Comparison of 2 Natural Language Processing Methods for Identification of Bleeding Among Critically Ill Patients.
Taggart M, Chapman WW, Steinberg BA, Ruckel S, Pregenzer-Wenzler A, Du Y, Ferraro J, Bucher BT, Lloyd-Jones DM, Rondina MT, Shah RU. Taggart M, et al. Among authors: rondina mt. JAMA Netw Open. 2018 Oct 5;1(6):e183451. doi: 10.1001/jamanetworkopen.2018.3451. JAMA Netw Open. 2018. PMID: 30646240 Free PMC article.
Another instance of each ML model was also trained on a sample of 450 notes, with equal numbers of bleeding-present and bleeding-absent notes. The notes were represented using term frequency-inverse document frequency vectors and global vectors for word representation. ...
Another instance of each ML model was also trained on a sample of 450 notes, with equal numbers of bleeding-present and bleeding-absent note …
Skeletal muscle ceramides and relationship with insulin sensitivity after 2 weeks of simulated sedentary behaviour and recovery in healthy older adults.
Reidy PT, McKenzie AI, Mahmassani Z, Morrow VR, Yonemura NM, Hopkins PN, Marcus RL, Rondina MT, Lin YK, Drummond MJ. Reidy PT, et al. Among authors: rondina mt. J Physiol. 2018 Nov;596(21):5217-5236. doi: 10.1113/JP276798. Epub 2018 Oct 9. J Physiol. 2018. PMID: 30194727 Free PMC article. Clinical Trial.
It is not known how insulin sensitivity is affected by modest short-term physical inactivity and recovery in healthy older adults, nor how insulin sensitivity is related to changes in serum and muscle ceramide content. ...However, ceramides were not related to changes in i …
It is not known how insulin sensitivity is affected by modest short-term physical inactivity and recovery in healthy older adults, no …
Screening for Occult Cancer in Patients With Unprovoked Venous Thromboembolism: A Systematic Review and Meta-analysis of Individual Patient Data.
van Es N, Le Gal G, Otten HM, Robin P, Piccioli A, Lecumberri R, Jara-Palomares L, Religa P, Rieu V, Rondina M, Beckers MM, Prandoni P, Salaun PY, Di Nisio M, Bossuyt PM, Büller HR, Carrier M. van Es N, et al. Among authors: rondina m. Ann Intern Med. 2017 Sep 19;167(6):410-417. doi: 10.7326/M17-0868. Epub 2017 Aug 22. Ann Intern Med. 2017. PMID: 28828492 Review.
LIMITATION: Variation in patient characteristics and extensive screening strategies; unavailability of long-term mortality data. CONCLUSION: Occult cancer is detected in 1 in 20 patients within a year of receiving a diagnosis of unprovoked VTE. ...
LIMITATION: Variation in patient characteristics and extensive screening strategies; unavailability of long-term mortality data. CONC …
Changes in Oral Anticoagulant Treatment Rates in Atrial Fibrillation before and after the Introduction of Direct Oral Anticoagulants.
Shah RU, Rupp AB, Mowery D, Zhang M, Stoddard G, Deshmukh V, Bray BE, Hess R, Rondina MT. Shah RU, et al. Among authors: rondina mt. Neuroepidemiology. 2016;47(3-4):201-209. doi: 10.1159/000455012. Epub 2017 Jan 31. Neuroepidemiology. 2016. PMID: 28135707
We examined OAC prescription rates over time and according to CHA2DS2VASc score using multivariable Poisson regression models, with an interaction term between risk score and year of AF diagnosis. RESULTS: Among 6,688 AF patients, 78% had CHA2DS2VASc scores 2, 51.6% of who …
We examined OAC prescription rates over time and according to CHA2DS2VASc score using multivariable Poisson regression models, with an inter …
Multi-complexity measures of heart rate variability and the effect of vasopressor titration: a prospective cohort study of patients with septic shock.
Brown SM, Sorensen J, Lanspa MJ, Rondina MT, Grissom CK, Shahul S, Mathews VJ. Brown SM, et al. Among authors: rondina mt. BMC Infect Dis. 2016 Oct 10;16(1):551. doi: 10.1186/s12879-016-1896-1. BMC Infect Dis. 2016. PMID: 27724850 Free PMC article. Clinical Trial.
The ratio of fractal exponents was not associated with successful up-titration on univariate or multivariate regression. On exploratory secondary analyses, however, the long-term fractal exponent was associated (p = 0.003) with success of up-titration. ...CONCLUSIONS: Only …
The ratio of fractal exponents was not associated with successful up-titration on univariate or multivariate regression. On exploratory seco …
15 results