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Cognitive Impairment in the 3xTg-AD Mouse Model of Alzheimer's Disease is Affected by Aβ-ImmunoTherapy and Cognitive Stimulation.
Roda AR, Esquerda-Canals G, Martí-Clúa J, Villegas S. Roda AR, et al. Pharmaceutics. 2020 Oct 2;12(10):944. doi: 10.3390/pharmaceutics12100944. Pharmaceutics. 2020. PMID: 33023109 Free PMC article.
Learning abilities of 3xTg-AD mice were not seriously compromised but an impairment in long-term spatial memory was evident at 5 months of age. Interestingly, scFv-h3D6-treatment affected the cognitive impairment displayed by 5-month-old 3xTg-AD mice. ...
Learning abilities of 3xTg-AD mice were not seriously compromised but an impairment in long-term spatial memory was evident at 5 mont …
Cutaneous Manifestations of Diabetes Mellitus and Prediabetes.
Sanches MM, Roda Â, Pimenta R, Filipe PL, Freitas JP. Sanches MM, et al. Among authors: roda a. Acta Med Port. 2019 Jun 28;32(6):459-465. doi: 10.20344/amp.10738. Acta Med Port. 2019. PMID: 31292028 Free article. Review.
The prompt recognition of these frequently underestimated entities is extremely important as it may trigger not only an adequate metabolic evaluation but also a timely referral and appropriate treatment, minimizing the secondary effects of long-term diabetes and improving …
The prompt recognition of these frequently underestimated entities is extremely important as it may trigger not only an adequate metabolic e …
Advanced biosensors for monitoring astronauts' health during long-duration space missions.
Roda A, Mirasoli M, Guardigli M, Zangheri M, Caliceti C, Calabria D, Simoni P. Roda A, et al. Biosens Bioelectron. 2018 Jul 15;111:18-26. doi: 10.1016/j.bios.2018.03.062. Epub 2018 Mar 31. Biosens Bioelectron. 2018. PMID: 29631159 Review.
Long-duration space missions pose important health concerns for astronauts, especially regarding the adverse effects of microgravity and exposure to high-energy cosmic rays. The long-term maintenance of crew health and performance mainly relies on prevention, early diagnos …
Long-duration space missions pose important health concerns for astronauts, especially regarding the adverse effects of microgravity and exp …
Long-term Administration of Nuclear Bile Acid Receptor FXR Agonist Prevents Spontaneous Hepatocarcinogenesis in Abcb4(-/-) Mice.
Cariello M, Peres C, Zerlotin R, Porru E, Sabbà C, Roda A, Moschetta A. Cariello M, et al. Among authors: roda a. Sci Rep. 2017 Sep 11;7(1):11203. doi: 10.1038/s41598-017-11549-7. Sci Rep. 2017. PMID: 28894223 Free PMC article.
Moreover, in Abcb4(-/-) mice INT-767 prevented fibrosis by reducing collagen expression and deposition. Thus, long term activation of FXR is able to reduce BA pool, reprogram BA metabolism and prevent HCC. ...
Moreover, in Abcb4(-/-) mice INT-767 prevented fibrosis by reducing collagen expression and deposition. Thus, long term activation of …
Berberine: New Insights from Pharmacological Aspects to Clinical Evidences in the Management of Metabolic Disorders.
Caliceti C, Franco P, Spinozzi S, Roda A, Cicero AF. Caliceti C, et al. Among authors: roda a. Curr Med Chem. 2016;23(14):1460-76. doi: 10.2174/0929867323666160411143314. Curr Med Chem. 2016. PMID: 27063256 Review.
A particular attention has also been given to the available clinical trials assessing its short- and middle- term use tolerability, safety and efficacy in various conditions, such as dyslipidaemia, impaired fasting glucose, metabolic syndrome and type 2 diabetes....
A particular attention has also been given to the available clinical trials assessing its short- and middle- term use tolerability, s …
Electronic nose and chiral-capillary electrophoresis in evaluation of the quality changes in commercial green tea leaves during a long-term storage.
Mirasoli M, Gotti R, Di Fusco M, Leoni A, Colliva C, Roda A. Mirasoli M, et al. Among authors: roda a. Talanta. 2014 Nov;129:32-8. doi: 10.1016/j.talanta.2014.04.044. Epub 2014 May 9. Talanta. 2014. PMID: 25127562
Electronic nose and capillary electrophoresis were applied in quality control of green tea samples subjected to long-term storage. Twelve representative green teas were considered, available as an "aged" (tea leaves stored during a long-term period of two years) and …
Electronic nose and capillary electrophoresis were applied in quality control of green tea samples subjected to long-term storage. Tw …
Field-deployable whole-cell bioluminescent biosensors: so near and yet so far.
Michelini E, Cevenini L, Calabretta MM, Spinozzi S, Camborata C, Roda A. Michelini E, et al. Among authors: roda a. Anal Bioanal Chem. 2013 Jul;405(19):6155-63. doi: 10.1007/s00216-013-7043-6. Epub 2013 Jun 6. Anal Bioanal Chem. 2013. PMID: 23739749 Review.
To enable handling of cells as ready-to-use reagents, nature-inspired strategies have been used, with the objective of keeping cells in a dormant state until use. Several issues must still be investigated, for example long-term viability of cells, the possibility of perfor …
To enable handling of cells as ready-to-use reagents, nature-inspired strategies have been used, with the objective of keeping cells in a do …
Non-invasive panel tests for gastrointestinal motility monitoring within the MARS-500 Project.
Roda A, Mirasoli M, Guardigli M, Simoni P, Festi D, Afonin B, Vasilyeva G. Roda A, et al. World J Gastroenterol. 2013;19(14):2208-16. doi: 10.3748/wjg.v19.i14.2208. World J Gastroenterol. 2013. PMID: 23599647 Free PMC article.
AIM: To develop an integrated approach for monitoring gastrointestinal motility and inflammation state suitable for application in long-term spaceflights. METHODS: Breath tests based on the oral administration of 13C-labeled or hydrogen-producing substrates followed by the …
AIM: To develop an integrated approach for monitoring gastrointestinal motility and inflammation state suitable for application in long-t …
Staying alive: new perspectives on cell immobilization for biosensing purposes.
Michelini E, Roda A. Michelini E, et al. Among authors: roda a. Anal Bioanal Chem. 2012 Feb;402(5):1785-97. doi: 10.1007/s00216-011-5364-x. Epub 2011 Sep 16. Anal Bioanal Chem. 2012. PMID: 21922308 Review.
Cell immobilization, widely used in, for example, microbial biofermentors or bioremediation systems, is now emerging as an appealing way of integrating whole-cell biosensors into devices, to maintain long-term cell viability, to increase the reproducibility of the cell's r …
Cell immobilization, widely used in, for example, microbial biofermentors or bioremediation systems, is now emerging as an appealing way of …
Evaluation of short-term low-dose triple therapy for the eradication of Helicobacter pylori by factorial design in a randomized, double-blind, controlled study.
Bazzoli F, Zagari M, Pozzato P, Varoli O, Fossi S, Ricciardiello L, Alampi G, Nicolini G, Sottili S, Simoni P, Roda A, Roda E. Bazzoli F, et al. Among authors: roda a. Aliment Pharmacol Ther. 1998 May;12(5):439-45. doi: 10.1046/j.1365-2036.1998.00330.x. Aliment Pharmacol Ther. 1998. PMID: 9663723 Free article. Clinical Trial.
BACKGROUND: Studies demonstrating the efficacy of short-term low-dose triple therapies including omeprazole (O), clarithromycin (C) and a nitroimidazole (tinidazole, T) for Helicobacter pylori eradication have largely been open and uncontrolled, and have not assessed antib …
BACKGROUND: Studies demonstrating the efficacy of short-term low-dose triple therapies including omeprazole (O), clarithromycin (C) a …
12 results