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Neoadjuvant chemotherapy is associated with suppression of the B cell-centered immune landscape in pancreatic ductal adenocarcinoma.
Rupp L, Dietsche I, Kießler M, Sommer U, Muckenhuber A, Steiger K, van Eijck CWF, Richter L, Istvanffy R, Jäger C, Friess H, van Eijck CHJ, Demir IE, Reyes CM, Schmitz M. Rupp L, et al. Among authors: richter l. Front Immunol. 2024 Apr 2;15:1378190. doi: 10.3389/fimmu.2024.1378190. eCollection 2024. Front Immunol. 2024. PMID: 38629072 Free PMC article.
Gaining further insight into the underlying molecular mechanisms is crucial to overcome the intrinsic immunotherapy resistance of PDAC and develop novel strategies to improve the long-term outcome of PDAC patients....
Gaining further insight into the underlying molecular mechanisms is crucial to overcome the intrinsic immunotherapy resistance of PDAC and d …
Childhood adversity during the post-apartheid transition and COVID-19 stress independently predict adult PTSD risk in urban South Africa: A biocultural analysis of the stress sensitization hypothesis.
Kim AW, Said Mohamed R, Norris SA, Naicker S, Richter LM, Kuzawa CW. Kim AW, et al. Among authors: richter lm. Am J Biol Anthropol. 2023 Dec;182(4):620-631. doi: 10.1002/ajpa.24791. Epub 2023 Jun 7. Am J Biol Anthropol. 2023. PMID: 37283092
MATERIALS AND METHODS: Data came from 88 adults who participated in a follow-up study of a longitudinal birth cohort study in Soweto, South Africa. Childhood adversity and COVID-19 psychosocial stress were assessed as primary predictors of adult PTSD risk, and an interacti …
MATERIALS AND METHODS: Data came from 88 adults who participated in a follow-up study of a longitudinal birth cohort study in Soweto, …
Redefining Neurodevelopmental Impairment: Perspectives of Very Preterm Birth Stakeholders.
Synnes A, Chera A, Richter LL, Bone JN, Bourque CJ, Zhang-Jiang S, Pearce R, Janvier A, Luu TM. Synnes A, et al. Among authors: richter ll. Children (Basel). 2023 May 14;10(5):880. doi: 10.3390/children10050880. Children (Basel). 2023. PMID: 37238428 Free PMC article.
Children born very preterm are at risk of severe neurodevelopmental impairment, a composite endpoint that includes cerebral palsy, developmental delay, and hearing and visual impairment defined by medical professionals. We aimed to describe preterm birth stakeholders' pers …
Children born very preterm are at risk of severe neurodevelopmental impairment, a composite endpoint that includes cerebral palsy, developme …
Experiences of Mothers of Preterm Infants in the Neonatal Intensive Care Unit During the COVID-19 Pandemic.
Richter LL, Ku C, Mak MYY, Holsti L, Kieran E, Alonso-Prieto E, Ranger M. Richter LL, et al. Adv Neonatal Care. 2023 Aug 1;23(4):295-303. doi: 10.1097/ANC.0000000000001071. Epub 2023 Apr 10. Adv Neonatal Care. 2023. PMID: 37036932
BACKGROUND: The neonatal intensive care unit (NICU) stay following the birth of a preterm infant can be stressful and traumatic for families. ...IMPLICATIONS FOR RESEARCH: : Our results show that these changes heightened mothers' distress, but also had a modest positive im …
BACKGROUND: The neonatal intensive care unit (NICU) stay following the birth of a preterm infant can be stressful and traumatic for f …
Early-life stature, preschool cognitive development, schooling attainment, and cognitive functioning in adulthood: a prospective study in four birth cohorts.
Stein AD, Adair LS, Donati G, Wray C, Richter LM, Norris SA, Stein A, Martorell R, Ramirez-Zea M, Menezes AMB, Murray J, Victora C, Lee N, Bas I; COHORTS Group. Stein AD, et al. Among authors: richter lm. Lancet Glob Health. 2023 Jan;11(1):e95-e104. doi: 10.1016/S2214-109X(22)00448-X. Lancet Glob Health. 2023. PMID: 36521958 Free PMC article.
METHODS: In this cohort study, we used prospective longitudinal data collected in four birth cohorts from Brazil (born in 1993), Guatemala (born in 1969-77), the Philippines (born in 1983-84), and South Africa (born in 1990). ...Our results are consistent with the inferenc …
METHODS: In this cohort study, we used prospective longitudinal data collected in four birth cohorts from Brazil (born in 1993), Guat …
Data assimilation on mechanistic models of glucose metabolism predicts glycemic states in adolescents following bariatric surgery.
Richter LR, Albert BI, Zhang L, Ostropolets A, Zitsman JL, Fennoy I, Albers DJ, Hripcsak G. Richter LR, et al. Front Physiol. 2022 Nov 28;13:923704. doi: 10.3389/fphys.2022.923704. eCollection 2022. Front Physiol. 2022. PMID: 36518108 Free PMC article.
We show that data assimilation extracts knowledge from mechanistic models of glucose metabolism to infer future glycemic states from limited clinical data. This method can provide a pathway to predict long-term, post-surgical glycemic states by estimating the contributions …
We show that data assimilation extracts knowledge from mechanistic models of glucose metabolism to infer future glycemic states from limited …
Psychological legacies of intergenerational trauma under South African apartheid: Prenatal stress predicts greater vulnerability to the psychological impacts of future stress exposure during late adolescence and early adulthood in Soweto, South Africa.
Kim AW, Said Mohamed R, Norris SA, Richter LM, Kuzawa CW. Kim AW, et al. Among authors: richter lm. J Child Psychol Psychiatry. 2023 Jan;64(1):110-124. doi: 10.1111/jcpp.13672. Epub 2022 Jul 19. J Child Psychol Psychiatry. 2023. PMID: 35853622 Free PMC article.
We evaluate the intergenerational effects of prenatal stress experienced during apartheid on psychiatric morbidity among children at ages 17-18 and also assess the moderating effects of maternal age, social support, and past household adversity. METHODS: Participants come from …
We evaluate the intergenerational effects of prenatal stress experienced during apartheid on psychiatric morbidity among children at ages 17 …
Rethinking water, sanitation, and hygiene for human growth and development.
Momberg DJ, Voth-Gaeddert LE, Richter LM, Norris SA, Said-Mohamed R. Momberg DJ, et al. Among authors: richter lm. Glob Public Health. 2022 Dec;17(12):3815-3824. doi: 10.1080/17441692.2022.2036218. Epub 2022 Feb 19. Glob Public Health. 2022. PMID: 35184678
Life history theory emphasises plasticity in developmental and biological programming where conditions in early life, lead to long-term consequences for health and wellbeing. Studies linking water, sanitation, and hygiene, nutrition, and child growth and development have e …
Life history theory emphasises plasticity in developmental and biological programming where conditions in early life, lead to long-term …
The Long-Term Health and Human Capital Consequences of Adverse Childhood Experiences in the Birth to Thirty Cohort: Single, Cumulative, and Clustered Adversity.
Naicker SN, Ahun MN, Besharati S, Norris SA, Orri M, Richter LM. Naicker SN, et al. Among authors: richter lm. Int J Environ Res Public Health. 2022 Feb 5;19(3):1799. doi: 10.3390/ijerph19031799. Int J Environ Res Public Health. 2022. PMID: 35162821 Free PMC article.
This study aims to examine the link between adverse childhood experiences and adult human capital in a South African birth cohort and to test whether associations differ by measurement of adversity. Secondary analysis of data from the Birth to Thirty study was under …
This study aims to examine the link between adverse childhood experiences and adult human capital in a South African birth cohort and …
Gaps in Screening Recommendations Must Be Addressed to Protect Youth and Adults from Substance Use-Related Harm.
Vuolo L, Oster R, Hogue A, Richter L, O'Grady M, Dauber S. Vuolo L, et al. Among authors: richter l. Subst Use Misuse. 2022;57(1):157-160. doi: 10.1080/10826084.2021.1949607. Epub 2021 Sep 12. Subst Use Misuse. 2022. PMID: 34514947
Results: The lack of recommendation to screen adolescents represents a critical gap and highlights the need for research on adolescent substance use screening. While research is limited, available evidence shows short-term benefits from youth screening and early interventi …
Results: The lack of recommendation to screen adolescents represents a critical gap and highlights the need for research on adolescent subst …
60 results