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Dietary Methionine and Total Sulfur Amino Acid Restriction in Healthy Adults.
Richie JP Jr, Sinha R, Dong Z, Nichenametla SN, Ables GP, Ciccarella A, Sinha I, Calcagnotto AM, Chinchilli VM, Reinhart L, Orentreich D. Richie JP Jr, et al. J Nutr Health Aging. 2023;27(2):111-123. doi: 10.1007/s12603-023-1883-3. J Nutr Health Aging. 2023. PMID: 36806866 Free PMC article.
In the 65% SAAR group, plasma Met and Cys levels were significantly reduced by 15% and 13% respectively (P<0.05). CONCLUSION: These results suggest that many of the short-term beneficial effects of SAAR observed in animal models are translatable to humans and support fu …
In the 65% SAAR group, plasma Met and Cys levels were significantly reduced by 15% and 13% respectively (P<0.05). CONCLUSION: These resul …
Cumulative Consumption of Sulfur Amino Acids and Risk of Diabetes: A Prospective Cohort Study.
Dong Z, Richie JP Jr, Gao X, Al-Shaar L, Nichenametla SN, Shen B, Orentreich D. Dong Z, et al. Among authors: richie jp jr. J Nutr. 2022 Nov;152(11):2419-2428. doi: 10.1093/jn/nxac172. Epub 2022 Aug 9. J Nutr. 2022. PMID: 36774108 Free article.
BACKGROUND: Cross-sectional studies have suggested that consumption of sulfur amino acids (SAAs), including methionine and cysteine, is associated with a higher risk of type 2 diabetes (T2D) in humans and with T2D-related biomarkers in animals. But whether higher long-term …
BACKGROUND: Cross-sectional studies have suggested that consumption of sulfur amino acids (SAAs), including methionine and cysteine, is asso …
Is ergothioneine a 'longevity vitamin' limited in the American diet?
Beelman RB, Kalaras MD, Phillips AT, Richie JP Jr. Beelman RB, et al. Among authors: richie jp jr. J Nutr Sci. 2020 Nov 11;9:e52. doi: 10.1017/jns.2020.44. eCollection 2020. J Nutr Sci. 2020. PMID: 33244403 Free PMC article.
Thus, research is needed to further analyse the role agricultural practices play in the availability of ERGO in the human diet and its potential to improve our long-term health....
Thus, research is needed to further analyse the role agricultural practices play in the availability of ERGO in the human diet and its poten …
Randomized controlled trial of oral glutathione supplementation on body stores of glutathione.
Richie JP Jr, Nichenametla S, Neidig W, Calcagnotto A, Haley JS, Schell TD, Muscat JE. Richie JP Jr, et al. Eur J Nutr. 2015 Mar;54(2):251-63. doi: 10.1007/s00394-014-0706-z. Epub 2014 May 5. Eur J Nutr. 2015. PMID: 24791752 Clinical Trial.
While oral GSH has been shown to be bioavailable in laboratory animal models, its efficacy in humans has not been established. Our objective was to determine the long-term effectiveness of oral GSH supplementation on body stores of GSH in healthy adults. ...
While oral GSH has been shown to be bioavailable in laboratory animal models, its efficacy in humans has not been established. Our objective …
Lung cancer risk in white and black Americans.
Stellman SD, Chen Y, Muscat JE, Djordjevic MV, Richie JP Jr, Lazarus P, Thompson S, Altorki N, Berwick M, Citron ML, Harlap S, Kaur TB, Neugut AI, Olson S, Travaline JM, Witorsch P, Zhang ZF. Stellman SD, et al. Among authors: richie jp jr. Ann Epidemiol. 2003 Apr;13(4):294-302. doi: 10.1016/s1047-2797(02)00420-9. Ann Epidemiol. 2003. PMID: 12684197
Overall ORs were similar for blacks and whites, except among the heaviest smoking males (21+ cigarettes per day or 37.5 pack-years), in whom ORs for blacks were considerably greater than for whites. Long-term benefits of cessation were similar for white and black ex-smoker …
Overall ORs were similar for blacks and whites, except among the heaviest smoking males (21+ cigarettes per day or 37.5 pack-years), in whom …
Long-term stability of blood glutathione and cysteine in humans.
Richie JP Jr, Abraham P, Leutzinger Y. Richie JP Jr, et al. Clin Chem. 1996 Jul;42(7):1100-5. Clin Chem. 1996. PMID: 8674195
To validate the use of blood GSH in population studies, we investigated the long-term intraindividual variation of blood GSH and cyst(e)ine (Cys and cystine) concentrations in healthy adults. ...The results demonstrate the stability of blood GSH in free-living subjects and …
To validate the use of blood GSH in population studies, we investigated the long-term intraindividual variation of blood GSH and cyst …
Intraindividual and interindividual differences in metabolites of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in smokers' urine.
Carmella SG, Akerkar SA, Richie JP Jr, Hecht SS. Carmella SG, et al. Among authors: richie jp jr. Cancer Epidemiol Biomarkers Prev. 1995 Sep;4(6):635-42. Cancer Epidemiol Biomarkers Prev. 1995. PMID: 8547830
Two phenotypes of this ratio were apparent; one ranging from 0 to 6 and found in 85% of the smokers and a second ranging from 6 to 11. The short-term and long-term consistency of the ratio was investigated. Studies carried out over a 4-5 day period indicated that th …
Two phenotypes of this ratio were apparent; one ranging from 0 to 6 and found in 85% of the smokers and a second ranging from 6 to 11. The s …