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Acute kidney injury after cytoreductive surgery and hyperthermic intraoperative cisplatin chemotherapy for malignant pleural mesothelioma.
Hod T, Freedberg KJ, Motwani SS, Chen M, Frendl G, Leaf DE, Gupta S, Mothi SS, Richards WG, Bueno R, Waikar SS. Hod T, et al. Among authors: richards wg. J Thorac Cardiovasc Surg. 2021 Apr;161(4):1510-1518. doi: 10.1016/j.jtcvs.2020.05.033. Epub 2020 May 29. J Thorac Cardiovasc Surg. 2021. PMID: 32631662 Free article.
CONCLUSIONS: Acute kidney injury is common after cytoreductive surgery with hyperthermic intraoperative chemotherapy with cisplatin and is associated with poor long-term outcomes. Strategies to prevent postoperative acute kidney injury are needed to improve multimodal trea …
CONCLUSIONS: Acute kidney injury is common after cytoreductive surgery with hyperthermic intraoperative chemotherapy with cisplatin and is a …
Long term impact of powered toothbrush on oral health.
Richards W, Coll AM, Filipponi T. Richards W, et al. Evid Based Dent. 2020 Mar;21(1):14-15. doi: 10.1038/s41432-020-0076-8. Evid Based Dent. 2020. PMID: 32221486
Similar trends were shown for CAL mean scores.Conclusions There are benefits of power toothbrush usage and long term protective effects on oral health in terms of reduced probing depths, clinical attachments and number of teeth lost....
Similar trends were shown for CAL mean scores.Conclusions There are benefits of power toothbrush usage and long term protective effec …
FGF23 impairs peripheral microvascular function in renal failure.
Verkaik M, Juni RP, van Loon EPM, van Poelgeest EM, Kwekkeboom RFJ, Gam Z, Richards WG, Ter Wee PM, Hoenderop JG, Eringa EC, Vervloet MG; NIGRAM Consortium. Verkaik M, et al. Among authors: richards wg. Am J Physiol Heart Circ Physiol. 2018 Nov 1;315(5):H1414-H1424. doi: 10.1152/ajpheart.00272.2018. Epub 2018 Jul 20. Am J Physiol Heart Circ Physiol. 2018. PMID: 30028196 Free article.
This pathological effect on endothelial cells was induced by long-term exposure of physiological levels of FGF23. Mechanistically, increased plasma asymmetric dimethylarginine concentrations were strongly associated with this endothelial dysfunction in CKD and were increas …
This pathological effect on endothelial cells was induced by long-term exposure of physiological levels of FGF23. Mechanistically, in …
CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation.
Deng J, Wang ES, Jenkins RW, Li S, Dries R, Yates K, Chhabra S, Huang W, Liu H, Aref AR, Ivanova E, Paweletz CP, Bowden M, Zhou CW, Herter-Sprie GS, Sorrentino JA, Bisi JE, Lizotte PH, Merlino AA, Quinn MM, Bufe LE, Yang A, Zhang Y, Zhang H, Gao P, Chen T, Cavanaugh ME, Rode AJ, Haines E, Roberts PJ, Strum JC, Richards WG, Lorch JH, Parangi S, Gunda V, Boland GM, Bueno R, Palakurthi S, Freeman GJ, Ritz J, Haining WN, Sharpless NE, Arthanari H, Shapiro GI, Barbie DA, Gray NS, Wong KK. Deng J, et al. Among authors: richards wg. Cancer Discov. 2018 Feb;8(2):216-233. doi: 10.1158/2159-8290.CD-17-0915. Epub 2017 Nov 3. Cancer Discov. 2018. PMID: 29101163 Free PMC article.
To enhance the efficacy of existing immunotherapies, we screened for small molecules capable of increasing the activity of T cells suppressed by PD-1. Here, we show that short-term exposure to small-molecule inhibitors of cyclin-dependent kinases 4 and 6 (CDK4/6) significa …
To enhance the efficacy of existing immunotherapies, we screened for small molecules capable of increasing the activity of T cells suppresse …
Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids.
Jenkins RW, Aref AR, Lizotte PH, Ivanova E, Stinson S, Zhou CW, Bowden M, Deng J, Liu H, Miao D, He MX, Walker W, Zhang G, Tian T, Cheng C, Wei Z, Palakurthi S, Bittinger M, Vitzthum H, Kim JW, Merlino A, Quinn M, Venkataramani C, Kaplan JA, Portell A, Gokhale PC, Phillips B, Smart A, Rotem A, Jones RE, Keogh L, Anguiano M, Stapleton L, Jia Z, Barzily-Rokni M, Cañadas I, Thai TC, Hammond MR, Vlahos R, Wang ES, Zhang H, Li S, Hanna GJ, Huang W, Hoang MP, Piris A, Eliane JP, Stemmer-Rachamimov AO, Cameron L, Su MJ, Shah P, Izar B, Thakuria M, LeBoeuf NR, Rabinowits G, Gunda V, Parangi S, Cleary JM, Miller BC, Kitajima S, Thummalapalli R, Miao B, Barbie TU, Sivathanu V, Wong J, Richards WG, Bueno R, Yoon CH, Miret J, Herlyn M, Garraway LA, Van Allen EM, Freeman GJ, Kirschmeier PT, Lorch JH, Ott PA, Hodi FS, Flaherty KT, Kamm RD, Boland GM, Wong KK, Dornan D, Paweletz CP, Barbie DA. Jenkins RW, et al. Among authors: richards wg. Cancer Discov. 2018 Feb;8(2):196-215. doi: 10.1158/2159-8290.CD-17-0833. Epub 2017 Nov 3. Cancer Discov. 2018. PMID: 29101162 Free PMC article.
MDOTS/PDOTS isolated from mouse and human tumors retain autologous lymphoid and myeloid cell populations and respond to ICB in short-term three-dimensional microfluidic culture. Response and resistance to ICB was recapitulated using MDOTS derived from established immunocom …
MDOTS/PDOTS isolated from mouse and human tumors retain autologous lymphoid and myeloid cell populations and respond to ICB in short-term …
Heller myotomy versus Heller myotomy with Dor fundoplication for achalasia: long-term symptomatic follow-up of a prospective randomized controlled trial.
Kummerow Broman K, Phillips SE, Faqih A, Kaiser J, Pierce RA, Poulose BK, Richards WO, Sharp KW, Holzman MD. Kummerow Broman K, et al. Among authors: richards wo. Surg Endosc. 2018 Apr;32(4):1668-1674. doi: 10.1007/s00464-017-5845-x. Epub 2017 Oct 18. Surg Endosc. 2018. PMID: 29046957 Clinical Trial.
Patient-reported outcomes are needed to determine whether the findings are sustained long-term. METHODS: We actively engaged participants from the prior randomized cohort, making up to six contact attempts per person using telephone, mail, and electronic messaging. ...Near …
Patient-reported outcomes are needed to determine whether the findings are sustained long-term. METHODS: We actively engaged particip …
VATS lobectomy has better perioperative outcomes than open lobectomy: CALGB 31001, an ancillary analysis of CALGB 140202 (Alliance).
Nwogu CE, D'Cunha J, Pang H, Gu L, Wang X, Richards WG, Veit LJ, Demmy TL, Sugarbaker DJ, Kohman LJ, Swanson SJ; Alliance for Clinical Trials in Oncology. Nwogu CE, et al. Among authors: richards wg. Ann Thorac Surg. 2015 Feb;99(2):399-405. doi: 10.1016/j.athoracsur.2014.09.018. Epub 2014 Dec 10. Ann Thorac Surg. 2015. PMID: 25499481 Free PMC article.
BACKGROUND: The short-term superiority of video-assisted thoracoscopic surgery lobectomy compared with open lobectomy for early-stage lung cancer has been suggested by single-institution studies. ...
BACKGROUND: The short-term superiority of video-assisted thoracoscopic surgery lobectomy compared with open lobectomy for early-stage …
Vascularized plantar myocutaneous free flap transfer for amputee stump preparation: a proof of concept cadaver study.
Smith LN, Richards WT, Mozingo DW, Lottenberg L. Smith LN, et al. Among authors: richards wt. Mil Med. 2013 Feb;178(2):222-7. doi: 10.7205/milmed-d-12-00298. Mil Med. 2013. PMID: 23495470
Lower extremity amputee stump ulceration, irritation, and pain have been a deterrent to consistent long-term or continuous use of lower extremity prosthetics. This study is the first in a series that hypothesizes that these complications can be minimized through the insett …
Lower extremity amputee stump ulceration, irritation, and pain have been a deterrent to consistent long-term or continuous use of low …
Hyperthermic intraoperative pleural cisplatin chemotherapy extends interval to recurrence and survival among low-risk patients with malignant pleural mesothelioma undergoing surgical macroscopic complete resection.
Sugarbaker DJ, Gill RR, Yeap BY, Wolf AS, DaSilva MC, Baldini EH, Bueno R, Richards WG. Sugarbaker DJ, et al. Among authors: richards wg. J Thorac Cardiovasc Surg. 2013 Apr;145(4):955-963. doi: 10.1016/j.jtcvs.2012.12.037. Epub 2013 Feb 21. J Thorac Cardiovasc Surg. 2013. PMID: 23434448 Free article.
OBJECTIVE: Local recurrence limits long-term survival in patients with malignant pleural mesothelioma. We investigated whether hyperthermic intraoperative cisplatin chemotherapy lavage affects the interval to recurrence and overall survival among patients with favorable pr …
OBJECTIVE: Local recurrence limits long-term survival in patients with malignant pleural mesothelioma. We investigated whether hypert …
Predicting resource utilization of elderly burn patients in the baby boomer era.
Richards WT, Richards WA, Miggins M, Liu H, Mozingo DW, Ang DN. Richards WT, et al. Among authors: richards wa. Am J Surg. 2013 Jan;205(1):29-34. doi: 10.1016/j.amjsurg.2012.05.002. Epub 2012 Sep 25. Am J Surg. 2013. PMID: 23017253 Free PMC article.
RESULTS: Elderly patients were discharged to home less often and were discharged to short-term general hospitals, intermediate-care facilities, and skilled nursing facilities more often than the other age groups (P < .05). ...
RESULTS: Elderly patients were discharged to home less often and were discharged to short-term general hospitals, intermediate-care f …
47 results