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Macitentan for the treatment of inoperable chronic thromboembolic pulmonary hypertension (MERIT-1): results from the multicentre, phase 2, randomised, double-blind, placebo-controlled study.
Ghofrani HA, Simonneau G, D'Armini AM, Fedullo P, Howard LS, Jaïs X, Jenkins DP, Jing ZC, Madani MM, Martin N, Mayer E, Papadakis K, Richard D, Kim NH; MERIT study investigators. Ghofrani HA, et al. Among authors: richard d. Lancet Respir Med. 2024 Apr;12(4):e21-e30. doi: 10.1016/S2213-2600(24)00027-4. Lancet Respir Med. 2024. PMID: 38548406 Clinical Trial.
BACKGROUND: Macitentan is beneficial for long-term treatment of pulmonary arterial hypertension. The microvasculopathy of chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension are similar. ...
BACKGROUND: Macitentan is beneficial for long-term treatment of pulmonary arterial hypertension. The microvasculopathy of chronic thr …
Impact of 24 h shifts on urinary catecholamine in emergency physicians: a cross-over randomized trial.
Dutheil F, Fournier A, Perrier C, Richard D, Trousselard M, Mnatzaganian G, Baker JS, Bagheri R, Mermillod M, Clinchamps M, Schmidt J, Bouillon-Minois JB. Dutheil F, et al. Among authors: richard d. Sci Rep. 2024 Mar 27;14(1):7329. doi: 10.1038/s41598-024-58070-2. Sci Rep. 2024. PMID: 38538760 Free PMC article. Clinical Trial.
Catecholamines are supposed to be chronic stress biomarker. However, no study has used catecholamines to assess short-term residual stress or measured them over multiple shifts. A shift-randomized trial was conducted to study urinary catecholamines levels of 17 emergency p …
Catecholamines are supposed to be chronic stress biomarker. However, no study has used catecholamines to assess short-term residual s …
How North Carolina Can Best Respond to Long-Term Services and Supports Needs.
Richard D, Sandoe E, Lea S. Richard D, et al. N C Med J. 2022 Nov-Dec;83(6):429-430. doi: 10.18043/ncm.83.6.429. N C Med J. 2022. PMID: 36344106 Free article.
Our long-term services and supports needs are growing, and North Carolinians have an opportunity to respond by working together across all sectors of care. ...
Our long-term services and supports needs are growing, and North Carolinians have an opportunity to respond by working together acros …
Transcriptomic profiling of cardiac tissues from SARS-CoV-2 patients identifies DNA damage.
Kulasinghe A, Liu N, Tan CW, Monkman J, Sinclair JE, Bhuva DD, Godbolt D, Pan L, Nam A, Sadeghirad H, Sato K, Bassi GL, O'Byrne K, Hartmann C, Dos Santos Miggiolaro AFR, Marques GL, Moura LZ, Richard D, Adams M, de Noronha L, Baena CP, Suen JY, Arora R, Belz GT, Short KR, Davis MJ, Guimaraes FS, Fraser JF. Kulasinghe A, et al. Among authors: richard d. Immunology. 2023 Mar;168(3):403-419. doi: 10.1111/imm.13577. Epub 2022 Sep 27. Immunology. 2023. PMID: 36107637 Free PMC article.
In comparison with the 2009 pandemic (pH1N1), SARS-CoV-2 infection is likely to lead to more severe disease, with multi-organ effects, including cardiovascular disease. SARS-CoV-2 has been associated with acute and long-term cardiovascular disease, but the molecular change …
In comparison with the 2009 pandemic (pH1N1), SARS-CoV-2 infection is likely to lead to more severe disease, with multi-organ effects, inclu …
Quantitative impact of pre-analytical process on plasma uracil when testing for dihydropyrimidine dehydrogenase deficiency.
Maillard M, Launay M, Royer B, Guitton J, Gautier-Veyret E, Broutin S, Tron C, Le Louedec F, Ciccolini J, Richard D, Alarcan H, Haufroid V, Tafzi N, Schmitt A, Etienne-Grimaldi MC, Narjoz C, Thomas F; Groupe de Pharmacologie Clinique Oncologique (GPCO). Maillard M, et al. Among authors: richard d. Br J Clin Pharmacol. 2023 Feb;89(2):762-772. doi: 10.1111/bcp.15536. Epub 2022 Oct 3. Br J Clin Pharmacol. 2023. PMID: 36104927 Free PMC article.
Stability in whole blood and plasma after centrifugation, the type of anticoagulant and long-term plasma storage were evaluated. The variation induced by time and temperature was calculated and compared to an acceptability range of 20%. ...
Stability in whole blood and plasma after centrifugation, the type of anticoagulant and long-term plasma storage were evaluated. The …
The past, current and future epidemiological dynamic of SARS-CoV-2.
Balloux F, Tan C, Swadling L, Richard D, Jenner C, Maini M, van Dorp L. Balloux F, et al. Among authors: richard d. Oxf Open Immunol. 2022 Jun 20;3(1):iqac003. doi: 10.1093/oxfimm/iqac003. eCollection 2022. Oxf Open Immunol. 2022. PMID: 35872966 Free PMC article. Review.
Considering what is known so far, we conclude by delineating scenarios for the future dynamic of SARS-CoV-2, ranging from the good-circulation of a fifth endemic 'common cold' coronavirus of potentially low virulence, the bad-a situation roughly comparable with seasonal flu, and …
Considering what is known so far, we conclude by delineating scenarios for the future dynamic of SARS-CoV-2, ranging from the good-circulati …
Prevalence and Management of Sexually Transmitted Infections in Correctional Settings: A Systematic Review.
Spaulding AC, Rabeeah Z, Del Mar González-Montalvo M, Akiyama MJ, Baker BJ, Bauer HM, Gibson BR, Nijhawan AE, Parvez F, Wangu Z, Chan PA; Rollins Investigational Team on STIs in Corrections. Spaulding AC, et al. Clin Infect Dis. 2022 Apr 13;74(Suppl_2):S193-S217. doi: 10.1093/cid/ciac122. Clin Infect Dis. 2022. PMID: 35416974 Free PMC article.
Following PRISMA guidelines, the authors present results of a systematic review of literature published since 2012 on STIs in US jails, prisons, Immigration and Customs Enforcement detention centers, and juvenile facilities. This updates an earlier review of STIs in short-term …
Following PRISMA guidelines, the authors present results of a systematic review of literature published since 2012 on STIs in US jails, pris …
The impact of COVID-19 on cardiovascular health behaviors in student veterans.
Canjar MR, Richard DL, Kappus RM. Canjar MR, et al. Among authors: richard dl. Nutr Metab Cardiovasc Dis. 2022 Mar;32(3):727-733. doi: 10.1016/j.numecd.2021.12.017. Epub 2021 Dec 22. Nutr Metab Cardiovasc Dis. 2022. PMID: 35109995 Free PMC article.
These results highlight the need for resources and interventions for our student veterans and suggest long-term cardiovascular consequences for all students who suffered through the COVID-19 pandemic....
These results highlight the need for resources and interventions for our student veterans and suggest long-term cardiovascular conseq …
The Complex Epidemiological Relationship between Flooding Events and Human Outbreaks of Mosquito-Borne Diseases: A Scoping Review.
Coalson JE, Anderson EJ, Santos EM, Madera Garcia V, Romine JK, Dominguez B, Richard DM, Little AC, Hayden MH, Ernst KC. Coalson JE, et al. Among authors: richard dm. Environ Health Perspect. 2021 Sep;129(9):96002. doi: 10.1289/EHP8887. Epub 2021 Sep 28. Environ Health Perspect. 2021. PMID: 34582261 Free PMC article. Review.
RESULTS: From 3,008 initial results, we included 131 relevant studies (dengue n = 45, malaria n = 61, other MBD n = 49). Dengue studies indicated short-term ( < 1 month) decreases and subsequent (1-4 month) increases in incidence. ...
RESULTS: From 3,008 initial results, we included 131 relevant studies (dengue n = 45, malaria n = 61, other MBD n = 49). Dengue studies indi …
47 results