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Predictors of asthma control differ from predictors of asthma attacks in children: The Swiss Paediatric Airway Cohort.
Ardura-Garcia C, Mallet MC, Berger DO, Hoyler K, Jochmann A, Kuhn A, Moeller A, Regamey N, Singer F, Pedersen ESL, Kuehni CE; SPAC Study Team. Ardura-Garcia C, et al. Among authors: regamey n. Clin Exp Allergy. 2023 Nov;53(11):1177-1186. doi: 10.1111/cea.14390. Epub 2023 Sep 2. Clin Exp Allergy. 2023. PMID: 37658735 Free article.
Lung function, exhaled nitric oxide (FeNO) and allergic sensitization at baseline were not associated with control or attacks. CONCLUSION: Children at risk of long-term suboptimal asthma control differ from those at risk of attacks. ...
Lung function, exhaled nitric oxide (FeNO) and allergic sensitization at baseline were not associated with control or attacks. CONCLUSION: C …
ABCA3-related interstitial lung disease beyond infancy.
Li Y, Seidl E, Knoflach K, Gothe F, Forstner ME, Michel K, Pawlita I, Gesenhues F, Sattler F, Yang X, Kroener C, Reu-Hofer S, Ley-Zaporozhan J, Kammer B, Krüger-Stollfuß I, Dinkel J, Carlens J, Wetzke M, Moreno-Galdó A, Torrent-Vernetta A, Lange J, Krenke K, Rumman N, Mayell S, Sismanlar T, Aslan A, Regamey N, Proesmans M, Stehling F, Naehrlich L, Ayse K, Becker S, Koerner-Rettberg C, Plattner E, Manali ED, Papiris SA, Campo I, Kappler M, Schwerk N, Griese M. Li Y, et al. Among authors: regamey n. Thorax. 2023 Jun;78(6):587-595. doi: 10.1136/thorax-2022-219434. Epub 2023 Feb 20. Thorax. 2023. PMID: 36808083 Free PMC article.
METHOD: Over a 21-year period, patients diagnosed as chILD due to ABCA3 deficiency were identified from the Kids Lung Register database. 44 patients survived beyond the first year of life and their long-term clinical course, oxygen supplementation and pulmonary function we …
METHOD: Over a 21-year period, patients diagnosed as chILD due to ABCA3 deficiency were identified from the Kids Lung Register database. 44 …
Immunoreactive trypsinogen in healthy newborns and infants with cystic fibrosis.
Fingerhut R, Rueegg CS, Imahorn O, Pedersen ESL, Kuehni CE, Gallati S, Regamey N, Barben J. Fingerhut R, et al. Among authors: regamey n. Arch Dis Child Fetal Neonatal Ed. 2023 Mar;108(2):176-181. doi: 10.1136/archdischild-2021-323549. Epub 2022 Sep 8. Arch Dis Child Fetal Neonatal Ed. 2023. PMID: 36351789
Among all samples analysed, mean IRT Z-Scores were higher for newborns with GA <33 weeks and 43 weeks (all Z-Scores >0.11) compared with term babies (all Z-Scores 0.06). Repeated IRT Z-Scores after a median (IQR) of 19 (17-22) days remained high for infants with CF w …
Among all samples analysed, mean IRT Z-Scores were higher for newborns with GA <33 weeks and 43 weeks (all Z-Scores >0.11) compared wi …
The Swiss Paediatric Airway Cohort (SPAC).
Pedersen ESL, de Jong CCM, Ardura-Garcia C, Barben J, Casaulta C, Frey U, Jochmann A, Latzin P, Moeller A, Regamey N, Singer F, Spycher B, Sutter O, Goutaki M, Kuehni CE. Pedersen ESL, et al. Among authors: regamey n. ERJ Open Res. 2018 Nov 20;4(4):00050-2018. doi: 10.1183/23120541.00050-2018. eCollection 2018 Oct. ERJ Open Res. 2018. PMID: 30474037 Free PMC article.
The SPAC will address important questions about clinical phenotypes, diagnosis, treatment, and the short- and long-term prognosis of common respiratory problems in children. The cohort currently consists of 347 patients from four major hospitals (Bern, Zurich, Basel and Lu …
The SPAC will address important questions about clinical phenotypes, diagnosis, treatment, and the short- and long-term prognosis of …
Lung disease caused by ABCA3 mutations.
Kröner C, Wittmann T, Reu S, Teusch V, Klemme M, Rauch D, Hengst M, Kappler M, Cobanoglu N, Sismanlar T, Aslan AT, Campo I, Proesmans M, Schaible T, Terheggen-Lagro S, Regamey N, Eber E, Seidenberg J, Schwerk N, Aslanidis C, Lohse P, Brasch F, Zarbock R, Griese M. Kröner C, et al. Among authors: regamey n. Thorax. 2017 Mar;72(3):213-220. doi: 10.1136/thoraxjnl-2016-208649. Epub 2016 Aug 11. Thorax. 2017. PMID: 27516224
RESULTS: Of 22 homozygous (15 male) and 18 compound heterozygous patients (3 male), 37 presented with neonatal respiratory distress syndrome as term babies. At follow-up, two major phenotypes are documented: patients with (1) early lethal mutations subdivided into (1a) dyi …
RESULTS: Of 22 homozygous (15 male) and 18 compound heterozygous patients (3 male), 37 presented with neonatal respiratory distress syndrome …
Rhinovirus Infections and Associated Respiratory Morbidity in Infants: A Prospective Cohort Study.
Mack I, Kieninger E, Cangiano G, Tapparel C, Kuehni C, Spycher B, Kaiser L, Frey U, Regamey N, Latzin P. Mack I, et al. Among authors: regamey n. Pediatr Infect Dis J. 2016 Oct;35(10):1069-74. doi: 10.1097/INF.0000000000001240. Pediatr Infect Dis J. 2016. PMID: 27254029
OBJECTIVES: To determine the frequency of symptomatic and asymptomatic RV infections and identify possible risk factors from host and environment among otherwise healthy infants. METHODS: In a prospective birth cohort, respiratory health was assessed in 41 term-born …
OBJECTIVES: To determine the frequency of symptomatic and asymptomatic RV infections and identify possible risk factors from host and enviro …
Persistent Tachypnea of Infancy. Usual and Aberrant.
Rauch D, Wetzke M, Reu S, Wesselak W, Schams A, Hengst M, Kammer B, Ley-Zaporozhan J, Kappler M, Proesmans M, Lange J, Escribano A, Kerem E, Ahrens F, Brasch F, Schwerk N, Griese M; PTI (Persistent Tachypnea of Infancy) Study Group of the Kids Lung Register. Rauch D, et al. Am J Respir Crit Care Med. 2016 Feb 15;193(4):438-47. doi: 10.1164/rccm.201508-1655OC. Am J Respir Crit Care Med. 2016. PMID: 26474448 Free article.
OBJECTIVES: To determine whether infants with the characteristic clinical presentation and computed tomographic (CT) imaging of NEHI (referred to as "usual PTI") have long-term outcome and biopsy findings similar to those of infants with an aberrant presentation and/or wit …
OBJECTIVES: To determine whether infants with the characteristic clinical presentation and computed tomographic (CT) imaging of NEHI (referr …
[Transition - how adolescents with cystic fibrosis their parents experience the change from paediatric to adult care].
Becher C, Regamey N, Spichiger E. Becher C, et al. Among authors: regamey n. Pflege. 2014 Dec;27(6):359-68. doi: 10.1024/1012-5302/a000389. Pflege. 2014. PMID: 25416483 German.
The transcribed interviews were analysed according to the method of hermeneutic phenomenology. RESULTS: Positive and negative experiences with long term routine care in the paediatric service, general themes of adolescence and the quality of the relationship with paediatri …
The transcribed interviews were analysed according to the method of hermeneutic phenomenology. RESULTS: Positive and negative experiences wi …
Rhinovirus infections in infancy and early childhood.
Kieninger E, Fuchs O, Latzin P, Frey U, Regamey N. Kieninger E, et al. Among authors: regamey n. Eur Respir J. 2013 Feb;41(2):443-52. doi: 10.1183/09031936.00203511. Epub 2012 Jun 27. Eur Respir J. 2013. PMID: 22743674 Free article. Review.
They are the most frequent causative agents of both upper and lower respiratory tract infections in this age group and are associated with a broad variety of clinical outcomes, ranging from asymptomatic infections to severe respiratory disease requiring hospitalisation. In additi …
They are the most frequent causative agents of both upper and lower respiratory tract infections in this age group and are associated with a …
Impaired type I and type III interferon induction and rhinovirus control in human cystic fibrosis airway epithelial cells.
Vareille M, Kieninger E, Alves MP, Kopf BS, Möller A, Geiser T, Johnston SL, Edwards MR, Regamey N. Vareille M, et al. Among authors: regamey n. Thorax. 2012 Jun;67(6):517-25. doi: 10.1136/thoraxjnl-2011-200405. Epub 2012 Jan 2. Thorax. 2012. PMID: 22213737 Retracted.
BACKGROUND: Rhinoviruses are important triggers of pulmonary exacerbations and possible contributors to long-term respiratory morbidity in cystic fibrosis (CF), but mechanisms leading to rhinovirus-induced CF exacerbations are poorly understood. ...
BACKGROUND: Rhinoviruses are important triggers of pulmonary exacerbations and possible contributors to long-term respiratory morbidi …
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