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Four-year overall survival update from the phase III HIMALAYA study of tremelimumab plus durvalumab in unresectable hepatocellular carcinoma.
Sangro B, Chan SL, Kelley RK, Lau G, Kudo M, Sukeepaisarnjaroen W, Yarchoan M, De Toni EN, Furuse J, Kang YK, Galle PR, Rimassa L, Heurgué A, Tam VC, Van Dao T, Thungappa SC, Breder V, Ostapenko Y, Reig M, Makowsky M, Paskow MJ, Gupta C, Kurland JF, Negro A, Abou-Alfa GK; HIMALAYA investigators. Sangro B, et al. Ann Oncol. 2024 Feb 19:S0923-7534(24)00049-8. doi: 10.1016/j.annonc.2024.02.005. Online ahead of print. Ann Oncol. 2024. PMID: 38382875 Free article.
Long-term survivors with STRIDE (n = 103) included participants across clinically relevant subgroups, and 57.3% (59/103) had no reported subsequent anticancer therapy. ...Results continue to support the long-term benefits of STRIDE in a diverse population, reflectiv …
Long-term survivors with STRIDE (n = 103) included participants across clinically relevant subgroups, and 57.3% (59/103) had no repor …
Paramagnetic rim lesions predict greater long-term relapse rates and clinical progression over 10 years.
Reeves JA, Mohebbi M, Wicks T, Salman F, Bartnik A, Jakimovski D, Bergsland N, Schweser F, Weinstock-Guttman B, Dwyer MG, Zivadinov R. Reeves JA, et al. Mult Scler. 2024 Apr;30(4-5):535-545. doi: 10.1177/13524585241229956. Epub 2024 Feb 17. Mult Scler. 2024. PMID: 38366920 Free PMC article.
However, it remains unclear whether PRLs predict future, long-term disease progression. OBJECTIVES: The study aimed to assess whether baseline PRLs were associated with subsequent long-term (10 years) Expanded Disability Status Scale (EDSS) increase and relapse freq …
However, it remains unclear whether PRLs predict future, long-term disease progression. OBJECTIVES: The study aimed to assess whether …
Emergent technological variation in archaeological landscapes: a primate perspective.
Reeves JS, Proffitt T, Malaivijitnond S, Luncz LV. Reeves JS, et al. J R Soc Interface. 2023 Jun;20(203):20230118. doi: 10.1098/rsif.2023.0118. Epub 2023 Jun 21. J R Soc Interface. 2023. PMID: 37340784 Free PMC article.
These findings demonstrate how material patterns can emerge from long-term interactions between behaviour and environmental factors....
These findings demonstrate how material patterns can emerge from long-term interactions between behaviour and environmental factors.. …
A one-size-fits-all approach to data-sharing will not suffice in lifecourse research: a grounded theory study of data-sharing from the perspective of participants in a 50-year-old lifecourse study about health and development.
Reeves J, Treharne GJ, Ratima M, Theodore R, Edwards W, Poulton R. Reeves J, et al. BMC Med Res Methodol. 2023 May 16;23(1):118. doi: 10.1186/s12874-023-01940-6. BMC Med Res Methodol. 2023. PMID: 37194009 Free PMC article.
The aim of this qualitative study was to explore perspectives on data-sharing of participants in a birth cohort study. METHODS: Semi-structured interviews were conducted with 25 members of the Dunedin Multidisciplinary Health and Development Study when aged between 45 and …
The aim of this qualitative study was to explore perspectives on data-sharing of participants in a birth cohort study. METHODS: Semi- …
A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients.
Pita-Juarez Y, Karagkouni D, Kalavros N, Melms JC, Niezen S, Delorey TM, Essene AL, Brook OR, Pant D, Skelton-Badlani D, Naderi P, Huang P, Pan L, Hether T, Andrews TS, Ziegler CGK, Reeves J, Myloserdnyy A, Chen R, Nam A, Phelan S, Liang Y, Amin AD, Biermann J, Hibshoosh H, Veregge M, Kramer Z, Jacobs C, Yalcin Y, Phillips D, Slyper M, Subramanian A, Ashenberg O, Bloom-Ackermann Z, Tran VM, Gomez J, Sturm A, Zhang S, Fleming SJ, Warren S, Beechem J, Hung D, Babadi M, Padera RF Jr, MacParland SA, Bader GD, Imad N, Solomon IH, Miller E, Riedel S, Porter CBM, Villani AC, Tsai LT, Hide W, Szabo G, Hecht J, Rozenblatt-Rosen O, Shalek AK, Izar B, Regev A, Popov Y, Jiang ZG, Vlachos IS. Pita-Juarez Y, et al. Among authors: reeves j. bioRxiv [Preprint]. 2022 Oct 28:2022.10.27.514070. doi: 10.1101/2022.10.27.514070. bioRxiv. 2022. PMID: 36324805 Free PMC article. Preprint.
The molecular underpinnings of organ dysfunction in acute COVID-19 and its potential long-term sequelae are under intense investigation. To shed light on these in the context of liver function, we performed single-nucleus RNA-seq and spatial transcriptomic profiling of liv …
The molecular underpinnings of organ dysfunction in acute COVID-19 and its potential long-term sequelae are under intense investigati …
Examination of Diurnal Variation and Sex Differences in Hippocampal Neurophysiology and Spatial Memory.
Goode LK, Fusilier AR, Remiszewski N, Reeves JM, Abiraman K, Defenderfer M, Paul JR, McMahon LL, Gamble KL. Goode LK, et al. Among authors: reeves jm. eNeuro. 2022 Nov 15;9(6):ENEURO.0124-22.2022. doi: 10.1523/ENEURO.0124-22.2022. Print 2022 Nov-Dec. eNeuro. 2022. PMID: 36265903 Free PMC article.
Performance on the object location memory (OLM) task depended on both circadian time and sex, with memory enhanced at night in males but during the day in females. Long-term synaptic potentiation (LTP) magnitude at CA3-CA1 synapses was greater at night compared with day in …
Performance on the object location memory (OLM) task depended on both circadian time and sex, with memory enhanced at night in males but dur …
Early intervention with 3BNC117 and romidepsin at antiretroviral treatment initiation in people with HIV-1: a phase 1b/2a, randomized trial.
Gunst JD, Pahus MH, Rosás-Umbert M, Lu IN, Benfield T, Nielsen H, Johansen IS, Mohey R, Østergaard L, Klastrup V, Khan M, Schleimann MH, Olesen R, Støvring H, Denton PW, Kinloch NN, Copertino DC, Ward AR, Alberto WDC, Nielsen SD, Puertas MC, Ramos V, Reeves JD, Petropoulos CJ, Martinez-Picado J, Brumme ZL, Jones RB, Fox J, Tolstrup M, Nussenzweig MC, Caskey M, Fidler S, Søgaard OS. Gunst JD, et al. Among authors: reeves jd. Nat Med. 2022 Nov;28(11):2424-2435. doi: 10.1038/s41591-022-02023-7. Epub 2022 Oct 17. Nat Med. 2022. PMID: 36253609 Free PMC article. Clinical Trial.
These findings strongly support interventions administered at the time of ART initiation as a strategy to limit long-term HIV-1 persistence....
These findings strongly support interventions administered at the time of ART initiation as a strategy to limit long-term HIV-1 persi …
Healthcare aide-focused interventions to improve pain management in long-term care homes: A systematic review.
Knopp-Sihota JA, MacGregor T, Nuspl M, Reeves J, Kennedy M. Knopp-Sihota JA, et al. Among authors: reeves j. Arch Gerontol Geriatr. 2023 Jan;104:104808. doi: 10.1016/j.archger.2022.104808. Epub 2022 Sep 9. Arch Gerontol Geriatr. 2023. PMID: 36137462
OBJECTIVES: Pain is common in long-term care residents. We examined the effectiveness of interventions involving healthcare aides that aim to manage pain for these residents. ...SETTING AND PARTICIPANTS: We examined controlled trials and intervention studies that included …
OBJECTIVES: Pain is common in long-term care residents. We examined the effectiveness of interventions involving healthcare aides tha …
Rationale and design of ON-TRK: a novel prospective non-interventional study in patients with TRK fusion cancer treated with larotrectinib.
Yang JCH, Brose MS, Castro G, Kim ES, Lassen UN, Leyvraz S, Pappo A, López-Ríos F, Reeves JA, Fellous M, Penault-Llorca F, Rudzinski ER, Tabatabai G, Vassal G, Drilon A, Trent J. Yang JCH, et al. Among authors: reeves ja. BMC Cancer. 2022 Jun 7;22(1):625. doi: 10.1186/s12885-022-09687-x. BMC Cancer. 2022. PMID: 35672677 Free PMC article.
Patients < 18 years old will be enrolled under a 'pediatric' cohort regardless of tumor type and will be followed for 5 years to evaluate the risk of potential long-term adverse effects of larotrectinib on their growth and development. ...

Patients < 18 years old will be enrolled under a 'pediatric' cohort regardless of tumor type and will be followed for 5 years to evaluate

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56 results