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Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B trial): protocol for a mixed-methods process evaluation of a randomised controlled trial.
Aitken LM, Emerson LM, Kydonaki K, Blackwood B, Creagh-Brown B, Lone NI, McKenzie CA, Reade MC, Weir CJ, Wise MP, Walsh TS. Aitken LM, et al. Among authors: reade mc. BMJ Open. 2024 Apr 5;14(4):e081637. doi: 10.1136/bmjopen-2023-081637. BMJ Open. 2024. PMID: 38580355 Free PMC article.
INTRODUCTION: An association between deep sedation and adverse short-term outcomes has been demonstrated although this evidence has been inconsistent. ...
INTRODUCTION: An association between deep sedation and adverse short-term outcomes has been demonstrated although this evidence has b …
Transforming research to improve therapies for trauma in the twenty-first century.
Juffermans NP, Gözden T, Brohi K, Davenport R, Acker JP, Reade MC, Maegele M, Neal MD, Spinella PC. Juffermans NP, et al. Among authors: reade mc. Crit Care. 2024 Feb 13;28(1):45. doi: 10.1186/s13054-024-04805-6. Crit Care. 2024. PMID: 38350971 Free PMC article. Review.
Improvements have been made in optimizing initial care of trauma patients, both in prehospital systems as well as in the emergency department, and these have also favorably affected longer term outcomes. However, as specific treatments for bleeding are largely lacking, man …
Improvements have been made in optimizing initial care of trauma patients, both in prehospital systems as well as in the emergency departmen …
Australian Defence Force Global Health Engagement through malaria and other vectorborne disease programmes in the Pacific and Southeast Asia.
Reade MC, Auliff A, McPherson B, Edstein M. Reade MC, et al. BMJ Mil Health. 2023 May 10:e002335. doi: 10.1136/military-2022-002335. Online ahead of print. BMJ Mil Health. 2023. PMID: 37164364 Review.
Process and outcome measures were built into both programmes, providing partner nations with the necessary assurance that funding was being used effectively. The long-term nature of each programme engendered personal trust between individuals and cultural understanding bet …
Process and outcome measures were built into both programmes, providing partner nations with the necessary assurance that funding was being …
Short- and long-term outcomes of neutropenic cancer patients in intensive care according to requirement for invasive ventilation.
Mackintosh D, Way M, Reade MC, Dhanani J. Mackintosh D, et al. Among authors: reade mc. Intern Med J. 2020 May;50(5):603-611. doi: 10.1111/imj.14721. Intern Med J. 2020. PMID: 31841270
Although hospital survival in this population has improved, long-term outcomes of critically ill neutropenic cancer patients have not been well defined. ...Those patients who require IMV are at significantly increased risk of both short- and long-term mortality....
Although hospital survival in this population has improved, long-term outcomes of critically ill neutropenic cancer patients have not …
Bibliometric analysis of military trauma publications: 2000-2016.
Vickers ML, Coorey CP, Milinovich GJ, Eriksson L, Assoum M, Reade MC. Vickers ML, et al. Among authors: reade mc. J R Army Med Corps. 2018 Jul;164(3):142-149. doi: 10.1136/jramc-2017-000858. Epub 2018 Jan 13. J R Army Med Corps. 2018. PMID: 29331949 Review.
It is likely that the lessons of recent conflicts will continue to influence civilian medical practice, particularly regarding the long-term effects of blast-related TBI....
It is likely that the lessons of recent conflicts will continue to influence civilian medical practice, particularly regarding the long-t …
The association between sedation practices and duration of mechanical ventilation in intensive care.
Jarman A, Duke G, Reade M, Casamento A. Jarman A, et al. Among authors: reade m. Anaesth Intensive Care. 2013 May;41(3):311-5. doi: 10.1177/0310057X1304100306. Anaesth Intensive Care. 2013. PMID: 23659391
Over the eight-year observation period there were significant increases in the numbers of annual MV admissions and long-term (>96 hours) MV patients, but a decline in median duration of MV, tracheostomy rate, median ICU length-of-stay and median hospital length-of-stay. …
Over the eight-year observation period there were significant increases in the numbers of annual MV admissions and long-term (>96 …
Early intensive care sedation predicts long-term mortality in ventilated critically ill patients.
Shehabi Y, Bellomo R, Reade MC, Bailey M, Bass F, Howe B, McArthur C, Seppelt IM, Webb S, Weisbrodt L; Sedation Practice in Intensive Care Evaluation (SPICE) Study Investigators; ANZICS Clinical Trials Group. Shehabi Y, et al. Among authors: reade mc. Am J Respir Crit Care Med. 2012 Oct 15;186(8):724-31. doi: 10.1164/rccm.201203-0522OC. Epub 2012 Aug 2. Am J Respir Crit Care Med. 2012. PMID: 22859526
RATIONALE: Choice and intensity of early (first 48 h) sedation may affect short- and long-term outcome. OBJECTIVES: To investigate the relationships between early sedation and time to extubation, delirium, and hospital and 180-day mortality among ventilated critically ill …
RATIONALE: Choice and intensity of early (first 48 h) sedation may affect short- and long-term outcome. OBJECTIVES: To investigate th …
Differences in immune response may explain lower survival among older men with pneumonia.
Reade MC, Yende S, D'Angelo G, Kong L, Kellum JA, Barnato AE, Milbrandt EB, Dooley C, Mayr FB, Weissfeld L, Angus DC; Genetic and Inflammatory Markers of Sepsis Investigators. Reade MC, et al. Crit Care Med. 2009 May;37(5):1655-62. doi: 10.1097/CCM.0b013e31819da853. Crit Care Med. 2009. PMID: 19325487 Free PMC article.
Patterns of inflammatory, coagulation, and fibrinolysis biomarkers among men may explain reduced short-term and long-term survival....
Patterns of inflammatory, coagulation, and fibrinolysis biomarkers among men may explain reduced short-term and long-term surv …