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Design, Characterization and Pharmacokinetic-Pharmacodynamic Evaluation of Poloxamer and Kappa-Carrageenan-Based Dual-Responsive In Situ Gel of Nebivolol for Treatment of Open-Angle Glaucoma.
Pharmaceutics. 2023 Jan 25;15(2):405. doi: 10.3390/pharmaceutics15020405.
Pharmaceutics. 2023.
PMID: 36839727
Free PMC article.
Lower systemic exposure of the optimized gel indicates that the systemic side effects can be significantly reduced compared to the NEB suspension, particularly in the long-term management of glaucoma....
Lower systemic exposure of the optimized gel indicates that the systemic side effects can be significantly reduced compared to the NEB suspe …
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