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Page 1
State of the Science in Dried Blood Spots.
Freeman JD, Rosman LM, Ratcliff JD, Strickland PT, Graham DR, Silbergeld EK. Freeman JD, et al. Among authors: ratcliff jd. Clin Chem. 2018 Apr;64(4):656-679. doi: 10.1373/clinchem.2017.275966. Epub 2017 Nov 29. Clin Chem. 2018. PMID: 29187355 Review.
Strengths of DBS enable its application in most clinical and laboratory settings, and the removal of phlebotomy and the need for refrigeration have expanded biosampling to hard-to-reach and vulnerable populations. Weaknesses may limit adoption in the near term because DBS …
Strengths of DBS enable its application in most clinical and laboratory settings, and the removal of phlebotomy and the need for refrigerati …
Recurrent Neural Network based Time-Series Modeling for Long-term Prognosis Following Acute Traumatic Brain Injury.
Nayebi A, Tipirneni S, Foreman B, Ratcliff J, Reddy CK, Subbian V. Nayebi A, et al. Among authors: ratcliff j. AMIA Annu Symp Proc. 2022 Feb 21;2021:900-909. eCollection 2021. AMIA Annu Symp Proc. 2022. PMID: 35309007 Free PMC article.
We developed a prognostic model for longer-term outcome prediction in traumatic brain injury (TBI) using an attention-based recurrent neural network (RNN). ...
We developed a prognostic model for longer-term outcome prediction in traumatic brain injury (TBI) using an attention-based recurrent …
Clinical validation of optimised RT-LAMP for the diagnosis of SARS-CoV-2 infection.
Lim B, Ratcliff J, Nawrot DA, Yu Y, Sanghani HR, Hsu CC, Peto L, Evans S, Hodgson SH, Skeva A, Adam M, Panopoulou M, Zois CE, Poncin K, Vasudevan SR, Dai S, Ren S, Chang H, Cui Z, Simmonds P, Huang WE, Andersson MI. Lim B, et al. Among authors: ratcliff j. Sci Rep. 2021 Aug 10;11(1):16193. doi: 10.1038/s41598-021-95607-1. Sci Rep. 2021. PMID: 34376716 Free PMC article.
We then developed freeze-dried master mix for single step RT-LAMP reaction, simplifying the operation for end users and improving long-term storage and transportation. The assay can detect as low as 13 copies of SARS-CoV2 RNA per reaction (25-muL). ...
We then developed freeze-dried master mix for single step RT-LAMP reaction, simplifying the operation for end users and improving long-te …
Initial and intermediate-term treatment of the phantom thrombus (primary non-occlusive mural thrombus on normal arteries).
DeKornfeld GM, Boll J, Ziegler KR, Ratcliff J, Naslund TC, Garrard CL, Valentine RJ, Curci JA. DeKornfeld GM, et al. Among authors: ratcliff j. Vasc Med. 2018 Dec;23(6):549-554. doi: 10.1177/1358863X18788952. Epub 2018 Aug 19. Vasc Med. 2018. PMID: 30124120
In patients with a phantom thrombus, a strategy of therapeutic anticoagulation for management of the embolic source seems to be safe and effective over both the short and intermediate-term....
In patients with a phantom thrombus, a strategy of therapeutic anticoagulation for management of the embolic source seems to be safe and eff …
Assessment of cytokines, microRNA and patient related outcome measures in conversion disorder/functional neurological disorder (CD/FND): The CANDO clinical feasibility study.
van der Feltz-Cornelis C, Brabyn S, Ratcliff J, Varley D, Allgar V, Gilbody S, Clarke C, Lagos D. van der Feltz-Cornelis C, et al. Among authors: ratcliff j. Brain Behav Immun Health. 2021 Feb 24;13:100228. doi: 10.1016/j.bbih.2021.100228. eCollection 2021 May. Brain Behav Immun Health. 2021. PMID: 34589743 Free PMC article.
BACKGROUND: Conversion disorder/functional neurological disorder (CD/FND) occurs often in neurological settings and can lead to long-term distress, disability and demand on health care services. Systemic low-grade inflammation might play a role, however, the pathogenic mec …
BACKGROUND: Conversion disorder/functional neurological disorder (CD/FND) occurs often in neurological settings and can lead to long-term …
Intracranial Hypertension and Cerebral Perfusion Pressure Insults in Adult Hypertensive Intraventricular Hemorrhage: Occurrence and Associations With Outcome.
Ziai WC, Thompson CB, Mayo S, McBee N, Freeman WD, Dlugash R, Ullman N, Hao Y, Lane K, Awad I, Hanley DF; Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage (CLEAR III) Investigators. Ziai WC, et al. Crit Care Med. 2019 Aug;47(8):1125-1134. doi: 10.1097/CCM.0000000000003848. Crit Care Med. 2019. PMID: 31162192 Free PMC article. Clinical Trial.
CONCLUSIONS: Elevated intracranial pressure and inadequate cerebral perfusion pressure are not infrequent during extraventricular drainage for severe intraventricular hemorrhage, and level and duration predict higher short-term mortality and long-term mortality. Bur …
CONCLUSIONS: Elevated intracranial pressure and inadequate cerebral perfusion pressure are not infrequent during extraventricular drainage f …