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An artificial intelligence-generated model predicts 90-day survival in alcohol-associated hepatitis: A global cohort study.
Dunn W, Li Y, Singal AK, Simonetto DA, Díaz LA, Idalsoaga F, Ayares G, Arnold J, Ayala-Valverde M, Perez D, Gomez J, Escarate R, Fuentes-López E, Ramirez-Cadiz C, Morales-Arraez D, Zhang W, Qian S, Ahn JC, Buryska S, Mehta H, Dunn N, Waleed M, Stefanescu H, Bumbu A, Horhat A, Attar B, Agrawal R, Cabezas J, Echavaría V, Cuyàs B, Poca M, Soriano G, Sarin SK, Maiwall R, Jalal PK, Higuera-de-la-Tijera F, Kulkarni AV, Rao PN, Guerra-Salazar P, Skladaný L, Kubánek N, Prado V, Clemente-Sanchez A, Rincon D, Haider T, Chacko KR, Romero GA, Pollarsky FD, Restrepo JC, Toro LG, Yaquich P, Mendizabal M, Garrido ML, Marciano S, Dirchwolf M, Vargas V, Jiménez C, Hudson D, García-Tsao G, Ortiz G, Abraldes JG, Kamath PS, Arrese M, Shah VH, Bataller R, Arab JP. Dunn W, et al. Among authors: rao pn. Hepatology. 2024 Apr 12. doi: 10.1097/HEP.0000000000000883. Online ahead of print. Hepatology. 2024. PMID: 38607809
BACKGROUND AIMS: Alcohol-associated hepatitis (AH) poses significant short-term mortality. Existing prognostic models lack precision for 90-day mortality. ...
BACKGROUND AIMS: Alcohol-associated hepatitis (AH) poses significant short-term mortality. Existing prognostic models lack precision …
APASL clinical practice guidelines on the management of acute kidney injury in acute-on-chronic liver failure.
Maiwall R, Singh SP, Angeli P, Moreau R, Krag A, Singh V, Singal AK, Tan SS, Puri P, Mahtab M, Lau G, Ning Q, Sharma MK, Rao PN, Kapoor D, Gupta S, Duseja A, Wadhawan M, Jothimani D, Saigal S, Taneja S, Shukla A, Puri P, Govil D, Pandey G, Madan K, Eapen CE, Benjamin J, Chowdhury A, Singh S, Salao V, Yang JM, Hamid S, Shalimar, Jasuja S, Kulkarni AV, Niriella MA, Tevethia HV, Arora V, Mathur RP, Roy A, Jindal A, Saraf N, Verma N, De A, Choudhary NS, Mehtani R, Chand P, Rudra O, Sarin SK. Maiwall R, et al. Among authors: rao pn. Hepatol Int. 2024 Apr 5. doi: 10.1007/s12072-024-10650-0. Online ahead of print. Hepatol Int. 2024. PMID: 38578541
Acute-on-chronic liver failure (ACLF) is a syndrome that is characterized by the rapid development of organ failures predisposing these patients to a high risk of short-term early death. The main causes of organ failure in these patients are bacterial infections and system …
Acute-on-chronic liver failure (ACLF) is a syndrome that is characterized by the rapid development of organ failures predisposing these pati …
MELD 3.0 adequately predicts mortality and renal replacement therapy requirements in patients with alcohol-associated hepatitis.
Díaz LA, Fuentes-López E, Ayares G, Idalsoaga F, Arnold J, Valverde MA, Perez D, Gómez J, Escarate R, Villalón A, Ramírez CA, Hernandez-Tejero M, Zhang W, Qian S, Simonetto DA, Ahn JC, Buryska S, Dunn W, Mehta H, Agrawal R, Cabezas J, García-Carrera I, Cuyàs B, Poca M, Soriano G, Sarin SK, Maiwall R, Jalal PK, Abdulsada S, Higuera-de-la-Tijera F, Kulkarni AV, Rao PN, Salazar PG, Skladaný L, Bystrianska N, Clemente-Sanchez A, Villaseca-Gómez C, Haider T, Chacko KR, Romero GA, Pollarsky FD, Restrepo JC, Castro-Sanchez S, Toro LG, Yaquich P, Mendizabal M, Garrido ML, Marciano S, Dirchwolf M, Vargas V, Jiménez C, Louvet A, García-Tsao G, Roblero JP, Abraldes JG, Shah VH, Kamath PS, Arrese M, Singal AK, Bataller R, Arab JP. Díaz LA, et al. Among authors: rao pn. JHEP Rep. 2023 Mar 15;5(8):100727. doi: 10.1016/j.jhepr.2023.100727. eCollection 2023 Aug. JHEP Rep. 2023. PMID: 37456675 Free PMC article.
Using a global cohort, we assessed the ability of the MELD 3.0 score to predict short-term mortality in AH. METHODS: This was a retrospective cohort study of patients admitted to hospital with AH from 2009 to 2019. ...However, further prospective studies are needed to vali …
Using a global cohort, we assessed the ability of the MELD 3.0 score to predict short-term mortality in AH. METHODS: This was a retro …
Pathophysiology and management of liver cirrhosis: from portal hypertension to acute-on-chronic liver failure.
Jagdish RK, Roy A, Kumar K, Premkumar M, Sharma M, Rao PN, Reddy DN, Kulkarni AV. Jagdish RK, et al. Among authors: rao pn. Front Med (Lausanne). 2023 Jun 15;10:1060073. doi: 10.3389/fmed.2023.1060073. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37396918 Free PMC article. Review.
In contrast to the classical natural history of cirrhosis and its complications which follows an insidious trajectory, acute-on-chronic failure (ACLF) leads to a rapidly downhill course with high short-term mortality unless intervened at the early stages. The management of …
In contrast to the classical natural history of cirrhosis and its complications which follows an insidious trajectory, acute-on-chronic fail …
INASL-SAASL Consensus Statements on NAFLD Name Change to MAFLD.
Singh SP, Duseja A, Mahtab MA, Anirvan P, Acharya SK, Akbar SMF, Butt AS, Dassanayake A, De A, Dhakal GP, Hamid S, Madan K, Panigrahi MK, Rao PN, Saigal S, Satapathy SK, Shalimar, Shrestha A, Shukla A, Sudhamshu KC, Wijewantha H. Singh SP, et al. Among authors: rao pn. J Clin Exp Hepatol. 2023 May-Jun;13(3):518-522. doi: 10.1016/j.jceh.2022.12.011. Epub 2023 Jan 20. J Clin Exp Hepatol. 2023. PMID: 37250868 Review.
Proponents of name change to MAFLD opined that NAFLD does not reflect current knowledge, and the term MAFLD was suggested as a more appropriate overarching term. ...
Proponents of name change to MAFLD opined that NAFLD does not reflect current knowledge, and the term MAFLD was suggested as a more a …
Clinicopathological Profile and Outcome of a Large Cohort of Patients with Nonalcoholic Fatty Liver Disease from South Asia: Interim Results of the Indian Consortium on Nonalcoholic Fatty Liver Disease.
Duseja A, Singh SP, Mehta M, Shalimar, Venkataraman J, Mehta V, Devadas K, Kar SK, Goyal O, Nagral A, Saigal S, Nijhawan S, Praharaj D, Shukla A, Sharma B, Narayanasamy K, Kumar P, Rao PN, Arora A, Mehta R, Asati P, Ranjan P, Koshy A, Alam S, Mukewar S, Mukewar S, Mohan Prasad VG, Rastogi M, Sanyal AJ. Duseja A, et al. Among authors: rao pn. Metab Syndr Relat Disord. 2022 Apr;20(3):166-173. doi: 10.1089/met.2021.0104. Epub 2022 Jan 25. Metab Syndr Relat Disord. 2022. PMID: 35085026
Background: Previous data from South Asia and India had shown that patients with nonalcoholic fatty liver disease (NAFLD) have mild liver disease severity. There are no data regarding long-term clinical outcomes in patients with NAFLD from South Asia. The aim of the study …
Background: Previous data from South Asia and India had shown that patients with nonalcoholic fatty liver disease (NAFLD) have mild liver di …
Safety Assessment of Autologous Stem Cell Combination Therapy in Patients With Decompensated Liver Cirrhosis: A Pilot Study.
Sharma M, Pondugala PK, Jaggaihgari S, Mitnala S, Krishna VV, Jaishetwar G, Naik P, Kumar P, Kulkarni A, Gupta R, Singh JR, Darisetty S, Sekharan A, Reddy DN, Rao GV, Syeda F, Jagtap N, Rao PN. Sharma M, et al. Among authors: rao pn. J Clin Exp Hepatol. 2022 Jan-Feb;12(1):80-88. doi: 10.1016/j.jceh.2021.03.010. Epub 2021 Apr 2. J Clin Exp Hepatol. 2022. PMID: 35068788 Free PMC article.
BACKGROUND: Haematopoietic stem cell (HSC) infusion has demonstrated short-term improvement in liver functions in patients with chronic liver disease. ...
BACKGROUND: Haematopoietic stem cell (HSC) infusion has demonstrated short-term improvement in liver functions in patients with chron …
'First week' is the crucial period for deciding living donor liver transplantation in patients with acute-on-chronic liver failure.
Choudhury A, Vijayaraghavan R, Maiwall R, Kumar M, Duan Z, Yu C, Hamid SS, Jafri W, Butt AS, Devarbhavi H, Ning Q, Ma K, Tan SS, Shukla A, Dhiman R, Duseja A, Taneja S, Eapen CE, Goel A, Treeprasertsuk S, Al-Mahtab M, Ghazinyan H, Kim DJ, Sahu MK, Lee GH, Lesmana LA, Lesmana RC, Shah S, Abbas Z, Sollano JD, Rao PN, Kulkarni A, Shiha G, Shrestha A, Dokmeci A, Yuen MF, Payawal DA, Kalista KF, Prasad VGM, Lau GK, Karim F, Jain P, Kumar G, Arora V, Pamecha V, Sinha P, Sarin SK; APASL ACLF Research Consortium (AARC) for APASL ACLF Working Party. Choudhury A, et al. Among authors: rao pn. Hepatol Int. 2021 Dec;15(6):1376-1388. doi: 10.1007/s12072-021-10206-6. Epub 2021 Oct 4. Hepatol Int. 2021. PMID: 34608586
BACKGROUND AND AIMS: Acute-on-chronic liver failure (ACLF) is a rapidly progressive illness with high short-term mortality. Timely liver transplant (LT) may improve survival. ...
BACKGROUND AND AIMS: Acute-on-chronic liver failure (ACLF) is a rapidly progressive illness with high short-term mortality. Timely li …
Midodrine Improves the Tolerability of Diuretics in Patients with Acute-on-Chronic Liver Failure-A Pilot Study.
Kulkarni AV, Kumar P, Sharma M, Ravikumar ST, Tevethia H, Vasireddy S, Gupta R, Reddy DN, Rao PN. Kulkarni AV, et al. Among authors: rao pn. J Clin Exp Hepatol. 2021 Sep-Oct;11(5):573-578. doi: 10.1016/j.jceh.2020.12.002. Epub 2020 Dec 17. J Clin Exp Hepatol. 2021. PMID: 34511818 Free PMC article.
BACKGROUND: Acute-on-chronic liver failure (ACLF) is a syndrome of acute portal hypertension with high short-term mortality. ACLF patients have low mean arterial pressure (MAP), systemic vascular resistance, and high cardiac output. ...
BACKGROUND: Acute-on-chronic liver failure (ACLF) is a syndrome of acute portal hypertension with high short-term mortality. ACLF pat …
Comparative accuracy of prognostic models for short-term mortality in acute-on-chronic liver failure patients: CAP-ACLF.
Verma N, Dhiman RK, Singh V, Duseja A, Taneja S, Choudhury A, Sharma MK, Eapen CE, Devarbhavi H, Al Mahtab M, Shukla A, Hamid SS, Jafri W, Butt AS, Ning Q, Chen T, Tan SS, Lesmana LA, Lesmana CRA, Sahu MK, Hu J, Lee GH, Sood A, Midha V, Goyal O, Ghazinian H, Kim DJ, Treeprasertsuk S, Mohan Prasad VG, Dokmeci AK, Sollano JD, Shah S, Payawal DA, Rao PN, Kulkarni A, Lau GK, Duan Z, Chen Y, Yokosuka O, Abbas Z, Karim F, Chowdhury D, Prasad AS, Sarin SK; APASL ACLF Working Party. Verma N, et al. Among authors: rao pn. Hepatol Int. 2021 Jun;15(3):753-765. doi: 10.1007/s12072-021-10175-w. Epub 2021 Jun 25. Hepatol Int. 2021. PMID: 34173167
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