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Regression of Fibrosis Stage With Treatment Reduces Long-Term Risk of Liver Cancer in Patients With Hemochromatosis Caused by Mutation in HFE.
Bardou-Jacquet E, Morandeau E, Anderson GJ, Ramm GA, Ramm LE, Morcet J, Bouzille G, Dixon J, Clouston AD, Lainé F, Turlin B, Powell LW, Deugnier YM. Bardou-Jacquet E, et al. Among authors: ramm ga. Clin Gastroenterol Hepatol. 2020 Jul;18(8):1851-1857. doi: 10.1016/j.cgh.2019.10.010. Epub 2019 Oct 14. Clin Gastroenterol Hepatol. 2020. PMID: 31622736 Free article.
In patients with fibrosis regression to a stage F2 or less, the long-term risk for liver cancer is significantly reduced....
In patients with fibrosis regression to a stage F2 or less, the long-term risk for liver cancer is significantly reduced....
Diagnosing schistosomiasis-induced liver morbidity: implications for global control.
Olveda DU, Inobaya M, Olveda RM, Vinluan ML, Ng SK, Weerakoon K, McManus DP, Ramm GA, Harn DA, Li Y, Lam AK, Guevarra JR, Ross AG. Olveda DU, et al. Among authors: ramm ga. Int J Infect Dis. 2017 Jan;54:138-144. doi: 10.1016/j.ijid.2016.10.024. Epub 2016 Nov 2. Int J Infect Dis. 2017. PMID: 27816660 Free article.
CONCLUSIONS: The findings of this study demonstrated that praziquantel treatment had a short-term impact on both the prevalence and intensity of infection, but less of an impact on established morbidity. ...
CONCLUSIONS: The findings of this study demonstrated that praziquantel treatment had a short-term impact on both the prevalence and i …
Should HFE p.C282Y homozygotes with moderately elevated serum ferritin be treated? A randomised controlled trial comparing iron reduction with sham treatment (Mi-iron).
Ong SY, Dolling L, Dixon JL, Nicoll AJ, Gurrin LC, Wolthuizen M, Wood EM, Anderson GJ, Ramm GA, Allen KJ, Olynyk JK, Crawford D, Kava J, Ramm LE, Gow P, Durrant S, Powell LW, Delatycki MB. Ong SY, et al. Among authors: ramm ga. BMJ Open. 2015 Aug 12;5(8):e008938. doi: 10.1136/bmjopen-2015-008938. BMJ Open. 2015. PMID: 26270952 Free PMC article. Clinical Trial.
We present here methods for a study that aims to evaluate whether non-specific symptoms and hepatic fibrosis markers improve with short-term normalisation of SF in p.C282Y homozygotes with moderate elevation of SF. ...
We present here methods for a study that aims to evaluate whether non-specific symptoms and hepatic fibrosis markers improve with short-t …
Pathophysiology of iron toxicity.
Britton RS, Ramm GA, Olynyk J, Singh R, O'Neill R, Bacon BR. Britton RS, et al. Among authors: ramm ga. Adv Exp Med Biol. 1994;356:239-53. doi: 10.1007/978-1-4615-2554-7_26. Adv Exp Med Biol. 1994. PMID: 7887229 Review.
Reduced cellular ATP levels, impaired cellular calcium homeostasis, and damage to DNA may all contribute to hepatocellular injury in iron overload. Long-term dietary iron overload in rats can lead to increased collagen gene expression and hepatic fibrosis, perhaps due to a …
Reduced cellular ATP levels, impaired cellular calcium homeostasis, and damage to DNA may all contribute to hepatocellular injury in iron ov …