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C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation.
Nature. 2023 Oct;622(7983):611-618. doi: 10.1038/s41586-023-06607-2. Epub 2023 Sep 12.
Nature. 2023.
PMID: 37699522
Targeted delivery of the TcdB enzymatic domain, through fusion with a detoxified diphtheria toxin, into peptidergic sensory neurons that express exogeneous diphtheria toxin receptor (an approach we term toxogenetics) is sufficient to induce neurogenic inflammation and reca …
Targeted delivery of the TcdB enzymatic domain, through fusion with a detoxified diphtheria toxin, into peptidergic sensory neurons that exp …
Stress ulcer prophylaxis versus placebo-a blinded randomized control trial to evaluate the safety of two strategies in critically ill infants with congenital heart disease (SUPPRESS-CHD).
Mills KI, Albert BD, Bechard LJ, Duggan CP, Kaza A, Rakoff-Nahoum S, Vlamakis H, Sleeper LA, Newburger JW, Priebe GP, Mehta NM.
Mills KI, et al. Among authors: rakoff nahoum s.
Trials. 2020 Jun 29;21(1):590. doi: 10.1186/s13063-020-04513-w.
Trials. 2020.
PMID: 32600393
Free PMC article.
Registered 12 September 2018, https://clinicaltrials.gov/ct2/show/NCT03667703?term=SUPPRESS+CHD&draw=2&rank=1 . All WHO Trial Registration Data Set Criteria are met in this manuscript....
Registered 12 September 2018, https://clinicaltrials.gov/ct2/show/NCT03667703?term=SUPPRESS+CHD&draw=2&rank=1 . All WHO Trial …
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Distribution and storage of inflammatory memory in barrier tissues.
Ordovas-Montanes J, Beyaz S, Rakoff-Nahoum S, Shalek AK.
Ordovas-Montanes J, et al. Among authors: rakoff nahoum s.
Nat Rev Immunol. 2020 May;20(5):308-320. doi: 10.1038/s41577-019-0263-z. Epub 2020 Feb 3.
Nat Rev Immunol. 2020.
PMID: 32015472
Free PMC article.
Review.
To effectively inform future responses, these past experiences can be stored in cell types that are long-term residents or essential constituents of tissues. There is an emerging understanding that, in addition to antigen-specific immune cells, diverse haematopoietic, stro …
To effectively inform future responses, these past experiences can be stored in cell types that are long-term residents or essential …
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