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The effects of long-term lactate and high-intensity interval training (HIIT) on brain neuroplasticity of aged mice.
Lei Z, Mozaffaritabar S, Kawamura T, Koike A, Kolonics A, Kéringer J, Pinho RA, Sun J, Shangguan R, Radák Z. Lei Z, et al. Among authors: radak z. Heliyon. 2024 Jan 10;10(2):e24421. doi: 10.1016/j.heliyon.2024.e24421. eCollection 2024 Jan 30. Heliyon. 2024. PMID: 38293399 Free PMC article.
Subsequently, in the 2nd experiment, we investigated the long-term effects of 500 mg/kg lactate intervention and HIIT on brain neuroplasticity in aged mice (25-27 months). ...In summary, the present study proved that long-term HIIT and lactate treatment have positiv …
Subsequently, in the 2nd experiment, we investigated the long-term effects of 500 mg/kg lactate intervention and HIIT on brain neurop …
Long-term iron supplementation combined with vitamin B6 enhances maximal oxygen uptake and promotes skeletal muscle-specific mitochondrial biogenesis in rats.
Zhou L, Mozaffaritabar S, Kolonics A, Kawamura T, Koike A, Kéringer J, Gu Y, Karabanov R, Radák Z. Zhou L, et al. Among authors: radak z. Front Nutr. 2024 Jan 15;10:1335187. doi: 10.3389/fnut.2023.1335187. eCollection 2023. Front Nutr. 2024. PMID: 38288063 Free PMC article.
METHODS: In this study, we orally administered an iron-based supplement to rats for 30 consecutive days at a dosage of 0.66 mg iron/kg body weight and vitamin B6 at a dosage of 0.46 mg/kg. RESULTS: Our findings reveal that long-term iron supplementation, in combination wit …
METHODS: In this study, we orally administered an iron-based supplement to rats for 30 consecutive days at a dosage of 0.66 mg iron/kg body …
DNA methylation clock DNAmFitAge shows regular exercise is associated with slower aging and systemic adaptation.
Jokai M, Torma F, McGreevy KM, Koltai E, Bori Z, Babszki G, Bakonyi P, Gombos Z, Gyorgy B, Aczel D, Toth L, Osvath P, Fridvalszky M, Teglas T, Posa A, Kujach S, Olek R, Kawamura T, Seki Y, Suzuki K, Tanisawa K, Goto S, Kerepesi C, Boldogh I, Ba X, Davies KJA, Horvath S, Radak Z. Jokai M, et al. Among authors: radak z. Geroscience. 2023 Oct;45(5):2805-2817. doi: 10.1007/s11357-023-00826-1. Epub 2023 May 20. Geroscience. 2023. PMID: 37209203 Free PMC article.
Here, we examine the relationship between physical fitness and DNAm-based biomarkers in adults aged 33-88 with a wide range of physical fitness (including athletes with long-term training history). Higher levels of VO(2)max (rho = 0.2, p = 6.4E - 4, r = 0.19, p = 1.2E - 3) …
Here, we examine the relationship between physical fitness and DNAm-based biomarkers in adults aged 33-88 with a wide range of physical fitn …
Late-afternoon endurance exercise is more effective than morning endurance exercise at improving 24-h glucose and blood lipid levels.
Kim HK, Furuhashi S, Takahashi M, Chijiki H, Nanba T, Inami T, Radak Z, Sakamoto S, Shibata S. Kim HK, et al. Among authors: radak z. Front Endocrinol (Lausanne). 2022 Jul 19;13:957239. doi: 10.3389/fendo.2022.957239. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35928886 Free PMC article. Clinical Trial.
Therefore, the effects of exercise on glucose and blood lipid levels at different times of the day may differ. This study aimed to investigate the effects of short-term endurance exercise intervention in the morning versus late afternoon on 24-h blood glucose variability a …
Therefore, the effects of exercise on glucose and blood lipid levels at different times of the day may differ. This study aimed to investiga …
Issues on Trainability.
Radak Z, Taylor AW. Radak Z, et al. Front Physiol. 2022 Jan 24;12:790196. doi: 10.3389/fphys.2021.790196. eCollection 2021. Front Physiol. 2022. PMID: 35140629 Free PMC article. Review.
The most beneficial training load could easily be different for skeletal muscle, brain, the gastro-intestinal track, or the immune systems. Hence, the term of non-responders should be used with caution and just referred to a given organ, cell type, molecular signaling, or …
The most beneficial training load could easily be different for skeletal muscle, brain, the gastro-intestinal track, or the immune systems. …
Does Compression Sensory Axonopathy in the Proximal Tibia Contribute to Noncontact Anterior Cruciate Ligament Injury in a Causative Way?-A New Theory for the Injury Mechanism.
Sonkodi B, Bardoni R, Hangody L, Radák Z, Berkes I. Sonkodi B, et al. Among authors: radak z. Life (Basel). 2021 May 14;11(5):443. doi: 10.3390/life11050443. Life (Basel). 2021. PMID: 34069060 Free PMC article.
The presynaptic modulation of the primary sensory axons by the fatigued and microdamaged proprioceptive sensory fibers in the proximal tibia induces the activation of N-methyl-D-aspartate receptors in the dorsal horn of the spinal cord, through a process that could have long t
The presynaptic modulation of the primary sensory axons by the fatigued and microdamaged proprioceptive sensory fibers in the proximal tibia …
Physical Training Inhibits the Fibrosis Formation in Alzheimer's Disease Kidney Influencing the TGFβ Signaling Pathways.
Szegeczki V, Perényi H, Horváth G, Hinnah B, Tamás A, Radák Z, Ábrahám D, Zákány R, Reglodi D, Juhász T. Szegeczki V, et al. Among authors: radak z. J Alzheimers Dis. 2021;81(3):1195-1209. doi: 10.3233/JAD-201206. J Alzheimers Dis. 2021. PMID: 33896841 Free PMC article.
OBJECTIVE: A protective role of increased physical activity has been proven in AD and in kidney fibrosis, but it is not clear whether TGFbeta signalization is involved in this effect. METHODS: The effects of long-term training on fibrosis were investigated in the kidneys o …
OBJECTIVE: A protective role of increased physical activity has been proven in AD and in kidney fibrosis, but it is not clear whether TGFbet …
Exercise-mitigated sex-based differences in aging: from genetic alterations to heart performance.
Börzsei D, Priksz D, Szabó R, Bombicz M, Karácsonyi Z, Puskás LG, Fehér LZ, Radák Z, Kupai K, Berkó AM, Varga C, Juhász B, Pósa A. Börzsei D, et al. Among authors: radak z. Am J Physiol Heart Circ Physiol. 2021 Feb 1;320(2):H854-H866. doi: 10.1152/ajpheart.00643.2020. Epub 2020 Dec 18. Am J Physiol Heart Circ Physiol. 2021. PMID: 33337964 Free article.
Exercise-moderated fundamental genetic alterations may have contributed to the functional adaptation of the heart.NEW & NOTEWORTHY Voluntary exercise has proved to be an effective therapeutic tool to improve cardiac function in aged rats with clearly visible sex differences. …
Exercise-moderated fundamental genetic alterations may have contributed to the functional adaptation of the heart.NEW & NOTEWORTHY Volun …
Effects of Nitric Oxide Synthase Inhibition on Fiber-Type Composition, Mitochondrial Biogenesis, and SIRT1 Expression in Rat Skeletal Muscle.
Suwa M, Nakano H, Radak Z, Kumagai S. Suwa M, et al. Among authors: radak z. J Sports Sci Med. 2015 Aug 11;14(3):548-55. eCollection 2015 Sep. J Sports Sci Med. 2015. PMID: 26336341 Free PMC article.
The purpose of the present study was to investigate the influence of long-term inhibition of nitric oxide synthases (NOS) on the fiber-type composition, metabolic regulators such as and silent information regulator of transcription 1 (SIRT1) and peroxisome proliferator-act …
The purpose of the present study was to investigate the influence of long-term inhibition of nitric oxide synthases (NOS) on the fibe …
19 results