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β(1)-adrenergic receptor polymorphisms and response to β-blockade in the African-American study of kidney disease and hypertension (AASK).
Lee J, Aziz H, Liu L, Lipkowitz M, O'Connor DT, Richard E, Brophy V, Wassel CL, Blantz R; AASK Study Investigators; Bhatnagar V. Lee J, et al. Am J Hypertens. 2011 Jun;24(6):694-700. doi: 10.1038/ajh.2011.39. Epub 2011 Mar 17. Am J Hypertens. 2011. PMID: 21415838 Clinical Trial.
CONCLUSIONS: Ser49/Gly49 was predictive of blood pressure response to metoprolol only among more obese African Americans with early hypertensive nephrosclerosis. In contrast to other studies suggesting increased short-term responsiveness to beta-blockers with Arg389, Arg38 …
CONCLUSIONS: Ser49/Gly49 was predictive of blood pressure response to metoprolol only among more obese African Americans with early hyperten …
The role of translational research in addressing health disparities: a conceptual framework.
Fleming ES, Perkins J, Easa D, Conde JG, Baker RS, Southerland WM, Dottin R, Benabe JE, Ofili EO, Bond VC, McClure SA, Sayre MH, Beanan MJ, Norris KC. Fleming ES, et al. Ethn Dis. 2008 Spring;18(2 Suppl 2):S2-155-60. Ethn Dis. 2008. PMID: 18646340 Free PMC article.
Translational research has tremendous potential as a tool to reduce health disparities in the United States, but a lack of common understanding about the scope of this dynamic, multidisciplinary approach to research has limited its use. The term "translational research" is …
Translational research has tremendous potential as a tool to reduce health disparities in the United States, but a lack of common understand …