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Clinical Correlation of Multiple Sclerosis Immunopathologic Subtypes.
Tobin WO, Kalinowska-Lyszczarz A, Weigand SD, Guo Y, Tosakulwong N, Parisi JE, Metz I, Frischer JM, Lassmann H, Brück W, Linbo L, Lucchinetti CF. Tobin WO, et al. Neurology. 2021 Nov 9;97(19):e1906-e1913. doi: 10.1212/WNL.0000000000012782. Epub 2021 Sep 9. Neurology. 2021. PMID: 34504026 Free PMC article.
Similarly, patients with pattern III pathology were likely to have progressive disease compared to patients with patterns I or II when followed up for 5 years (24% overall, p = 0.49), with no differences in long-term survival, despite a more fulminant attack presentation. …
Similarly, patients with pattern III pathology were likely to have progressive disease compared to patients with patterns I or II when follo …
Inflammatory cortical demyelination in early multiple sclerosis.
Lucchinetti CF, Popescu BF, Bunyan RF, Moll NM, Roemer SF, Lassmann H, Brück W, Parisi JE, Scheithauer BW, Giannini C, Weigand SD, Mandrekar J, Ransohoff RM. Lucchinetti CF, et al. N Engl J Med. 2011 Dec 8;365(23):2188-97. doi: 10.1056/NEJMoa1100648. N Engl J Med. 2011. PMID: 22150037 Free PMC article.
Twenty-five patients with cortical demyelination had definite multiple sclerosis (81% of 31 patients who underwent long-term follow-up), as did 33 patients without cortical demyelination (72% of 46 patients who underwent long-term follow-up). ...
Twenty-five patients with cortical demyelination had definite multiple sclerosis (81% of 31 patients who underwent long-term follow-u …
Clinical and radiographic spectrum of pathologically confirmed tumefactive multiple sclerosis.
Lucchinetti CF, Gavrilova RH, Metz I, Parisi JE, Scheithauer BW, Weigand S, Thomsen K, Mandrekar J, Altintas A, Erickson BJ, König F, Giannini C, Lassmann H, Linbo L, Pittock SJ, Brück W. Lucchinetti CF, et al. Brain. 2008 Jul;131(Pt 7):1759-75. doi: 10.1093/brain/awn098. Epub 2008 Jun 5. Brain. 2008. PMID: 18535080 Free PMC article.
Although lesion size >5 cm was associated with a slightly higher EDSS at last follow-up, long-term prognosis in patients with disease duration >10 years was better (EDSS 1.5) compared with a population-based multiple sclerosis cohort matched for disease duration (EDS …
Although lesion size >5 cm was associated with a slightly higher EDSS at last follow-up, long-term prognosis in patients with dise …