Primary Outcome Measures in Pediatric Septic Shock Trials: A Systematic Review.
Menon K, McNally JD, Zimmerman JJ, Agus MS, O'Hearn K, Watson RS, Wong HR, Duffett M, Wypij D, Choong K.
Menon K, et al.
Pediatr Crit Care Med. 2017 Mar;18(3):e146-e154. doi: 10.1097/PCC.0000000000001078.
Pediatr Crit Care Med. 2017.
PMID: 28099233
Free PMC article.
Review.
CONCLUSIONS: Our review found that use of mortality alone as a primary outcome in pediatric septic shock trials was associated with significant limitations and that long-term patient-centered outcomes were not used in this setting. Composite outcomes incorporating mortalit …
CONCLUSIONS: Our review found that use of mortality alone as a primary outcome in pediatric septic shock trials was associated with signific …