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Dietary Emulsifier-Induced Low-Grade Inflammation Promotes Colon Carcinogenesis.
Viennois E, Merlin D, Gewirtz AT, Chassaing B. Viennois E, et al. Cancer Res. 2017 Jan 1;77(1):27-40. doi: 10.1158/0008-5472.CAN-16-1359. Epub 2016 Nov 7. Cancer Res. 2017. PMID: 27821485 Free PMC article.
The increased risks conferred by inflammatory bowel disease (IBD) to the development of colorectal cancer gave rise to the term "colitis-associated cancer" and the concept that inflammation promotes colon tumorigenesis. ...
The increased risks conferred by inflammatory bowel disease (IBD) to the development of colorectal cancer gave rise to the term "coli …
Biomarkers of Inflammatory Bowel Disease: From Classical Laboratory Tools to Personalized Medicine.
Viennois E, Zhao Y, Merlin D. Viennois E, et al. Inflamm Bowel Dis. 2015 Oct;21(10):2467-74. doi: 10.1097/MIB.0000000000000444. Inflamm Bowel Dis. 2015. PMID: 25985250 Free PMC article. Review.
The current method of diagnostic remains a critical challenge for physicians in part due to their invasiveness and also for their limitations in term of diagnosis, prognosis, disease activity and severity assessment, and therapeutic outcomes. ...
The current method of diagnostic remains a critical challenge for physicians in part due to their invasiveness and also for their limitation …
Leptin transcriptionally enhances peptide transporter (hPepT1) expression and activity via the cAMP-response element-binding protein and Cdx2 transcription factors.
Nduati V, Yan Y, Dalmasso G, Driss A, Sitaraman S, Merlin D. Nduati V, et al. J Biol Chem. 2007 Jan 12;282(2):1359-73. doi: 10.1074/jbc.M604267200. Epub 2006 Sep 8. J Biol Chem. 2007. PMID: 16963449 Free article.
To begin elucidating inflammatory hPepT1 signaling, we herein investigated the long term leptin treatments, on PepT1 expression and activity in Caco2-BBE cells, and began to reveal the involved signaling pathways. ...
To begin elucidating inflammatory hPepT1 signaling, we herein investigated the long term leptin treatments, on PepT1 expression and a …