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Year | Number of Results |
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2013 | 1 |
2018 | 3 |
2019 | 1 |
2024 | 0 |
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Page 1
Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose.
PLoS One. 2018 Dec 26;13(12):e0208973. doi: 10.1371/journal.pone.0208973. eCollection 2018.
PLoS One. 2018.
PMID: 30586434
Free PMC article.
To connect diet and molecular changes, here we performed short- and long-term feeding of mice with standard chow diet (SCD) and high-fat diet (HFD), with or without glucose or fructose supplementation, and quantified liver metabolites, 861 proteins, and 1,815 protein level …
To connect diet and molecular changes, here we performed short- and long-term feeding of mice with standard chow diet (SCD) and high- …
FoxO Transcription Factors Are Critical Regulators of Diabetes-Related Muscle Atrophy.
O'Neill BT, Bhardwaj G, Penniman CM, Krumpoch MT, Suarez Beltran PA, Klaus K, Poro K, Li M, Pan H, Dreyfuss JM, Nair KS, Kahn CR.
O'Neill BT, et al.
Diabetes. 2019 Mar;68(3):556-570. doi: 10.2337/db18-0416. Epub 2018 Dec 6.
Diabetes. 2019.
PMID: 30523026
Free PMC article.
These same genes were increased 1.4- to 3.3-fold in muscle from humans with type 1 diabetes after short-term insulin deprivation. Thus, FoxO-regulated genes play a rate-limiting role in increased protein degradation and muscle atrophy in insulin-deficient diabetes....
These same genes were increased 1.4- to 3.3-fold in muscle from humans with type 1 diabetes after short-term insulin deprivation. Thu …
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Attenuation of PKCδ enhances metabolic activity and promotes expansion of blood progenitors.
Rao TN, Gupta MK, Softic S, Wang LD, Jang YC, Thomou T, Bezy O, Kulkarni RN, Kahn CR, Wagers AJ.
Rao TN, et al.
EMBO J. 2018 Dec 14;37(24):e100409. doi: 10.15252/embj.2018100409. Epub 2018 Nov 16.
EMBO J. 2018.
PMID: 30446598
Free PMC article.
PKCdelta-deficient mice showed a pronounced increase in HSPC numbers, increased competence in reconstituting lethally irradiated recipients, enhanced long-term competitive advantage in serial transplantation studies, and an augmented HSPC recovery during stress. ...
PKCdelta-deficient mice showed a pronounced increase in HSPC numbers, increased competence in reconstituting lethally irradiated recipients, …
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Absence of diabetes and pancreatic exocrine dysfunction in a transgenic model of carboxyl-ester lipase-MODY (maturity-onset diabetes of the young).
Ræder H, Vesterhus M, El Ouaamari A, Paulo JA, McAllister FE, Liew CW, Hu J, Kawamori D, Molven A, Gygi SP, Njølstad PR, Kahn CR, Kulkarni RN.
Ræder H, et al.
PLoS One. 2013;8(4):e60229. doi: 10.1371/journal.pone.0060229. Epub 2013 Apr 2.
PLoS One. 2013.
PMID: 23565203
Free PMC article.
Following confirmation of murine pancreatic expression of the human transgene by real-time quantitative PCR, we phenotyped the mouse model fed a normal chow and compared it with mice fed a 60% high fat diet (HFD) as well as the effects of short-term and long-term ce …
Following confirmation of murine pancreatic expression of the human transgene by real-time quantitative PCR, we phenotyped the mouse model f …
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