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Page 1
Low-grade chronic inflammation and immune alterations in childhood and adolescent cancer survivors: A contribution to accelerated aging?
Sulicka-Grodzicka J, Surdacki A, Seweryn M, Mikołajczyk T, Rewiuk K, Guzik T, Grodzicki T. Sulicka-Grodzicka J, et al. Cancer Med. 2021 Mar;10(5):1772-1782. doi: 10.1002/cam4.3788. Epub 2021 Feb 19. Cancer Med. 2021. PMID: 33605556 Free PMC article.
BACKGROUND: The long-term consequences of chemotherapy and radiotherapy result in a high prevalence and early onset of age-related chronic diseases in survivors. ...
BACKGROUND: The long-term consequences of chemotherapy and radiotherapy result in a high prevalence and early onset of age-related ch …
Association of Circulating Monocyte Chemoattractant Protein-1 Levels With Cardiovascular Mortality: A Meta-analysis of Population-Based Studies.
Georgakis MK, de Lemos JA, Ayers C, Wang B, Björkbacka H, Pana TA, Thorand B, Sun C, Fani L, Malik R, Dupuis J, Engström G, Orho-Melander M, Melander O, Boekholdt SM, Zierer A, Elhadad MA, Koenig W, Herder C, Hoogeveen RC, Kavousi M, Ballantyne CM, Peters A, Myint PK, Nilsson J, Benjamin EJ, Dichgans M. Georgakis MK, et al. JAMA Cardiol. 2021 May 1;6(5):587-592. doi: 10.1001/jamacardio.2020.5392. JAMA Cardiol. 2021. PMID: 33146689 Free PMC article.
CONCLUSIONS AND RELEVANCE: Higher circulating MCP-1 levels are associated with higher long-term cardiovascular mortality in community-dwelling individuals free of overt cardiovascular disease. ...
CONCLUSIONS AND RELEVANCE: Higher circulating MCP-1 levels are associated with higher long-term cardiovascular mortality in community …
Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke: Meta-Analysis of Population-Based Studies Involving 17 180 Individuals.
Georgakis MK, Malik R, Björkbacka H, Pana TA, Demissie S, Ayers C, Elhadad MA, Fornage M, Beiser AS, Benjamin EJ, Boekholdt SM, Engström G, Herder C, Hoogeveen RC, Koenig W, Melander O, Orho-Melander M, Schiopu A, Söderholm M, Wareham N, Ballantyne CM, Peters A, Seshadri S, Myint PK, Nilsson J, de Lemos JA, Dichgans M. Georgakis MK, et al. Circ Res. 2019 Sep 27;125(8):773-782. doi: 10.1161/CIRCRESAHA.119.315380. Epub 2019 Sep 3. Circ Res. 2019. PMID: 31476962 Free PMC article.
Conclusions: Higher circulating levels of MCP-1 are associated with increased long-term risk of stroke. Our findings along with genetic and experimental evidence suggest that MCP-1 signaling might represent a therapeutic target to lower stroke risk.Visual Overview: An onli …
Conclusions: Higher circulating levels of MCP-1 are associated with increased long-term risk of stroke. Our findings along with genet …
Short-term exposure to ambient air pollution and circulating biomarkers of endothelial cell activation: The Framingham Heart Study.
Li W, Dorans KS, Wilker EH, Rice MB, Ljungman PL, Schwartz JD, Coull BA, Koutrakis P, Gold DR, Keaney JF Jr, Vasan RS, Benjamin EJ, Mittleman MA. Li W, et al. Environ Res. 2019 Apr;171:36-43. doi: 10.1016/j.envres.2018.10.027. Epub 2018 Oct 28. Environ Res. 2019. PMID: 30654247 Free PMC article.
BACKGROUND: Short-term exposure to air pollution has been associated with cardiovascular events, potentially by promoting endothelial cell activation and inflammation. ...CONCLUSIONS: We did not find evidence of positive associations between short-term air pollution …
BACKGROUND: Short-term exposure to air pollution has been associated with cardiovascular events, potentially by promoting endothelial …
Short-Term Exposure to Ambient Air Pollution and Biomarkers of Systemic Inflammation: The Framingham Heart Study.
Li W, Dorans KS, Wilker EH, Rice MB, Ljungman PL, Schwartz JD, Coull BA, Koutrakis P, Gold DR, Keaney JF Jr, Vasan RS, Benjamin EJ, Mittleman MA. Li W, et al. Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1793-1800. doi: 10.1161/ATVBAHA.117.309799. Epub 2017 Jul 27. Arterioscler Thromb Vasc Biol. 2017. PMID: 28751572 Free PMC article.
OBJECTIVE: The objective of this study is to examine associations between short-term exposure to ambient air pollution and circulating biomarkers of systemic inflammation in participants from the Framingham Offspring and Third Generation cohorts in the greater Boston area. …
OBJECTIVE: The objective of this study is to examine associations between short-term exposure to ambient air pollution and circulatin …
50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study.
Schnabel RB, Yin X, Gona P, Larson MG, Beiser AS, McManus DD, Newton-Cheh C, Lubitz SA, Magnani JW, Ellinor PT, Seshadri S, Wolf PA, Vasan RS, Benjamin EJ, Levy D. Schnabel RB, et al. Lancet. 2015 Jul 11;386(9989):154-62. doi: 10.1016/S0140-6736(14)61774-8. Epub 2015 May 7. Lancet. 2015. PMID: 25960110 Free PMC article.
BACKGROUND: Comprehensive long-term data on atrial fibrillation trends in men and women are scant. ...
BACKGROUND: Comprehensive long-term data on atrial fibrillation trends in men and women are scant. ...
Atrial fibrillation patterns and risks of subsequent stroke, heart failure, or death in the community.
Lubitz SA, Moser C, Sullivan L, Rienstra M, Fontes JD, Villalon ML, Pai M, McManus DD, Schnabel RB, Magnani JW, Yin X, Levy D, Pencina MJ, Larson MG, Ellinor PT, Benjamin EJ. Lubitz SA, et al. J Am Heart Assoc. 2013 Sep 3;2(5):e000126. doi: 10.1161/JAHA.113.000126. J Am Heart Assoc. 2013. PMID: 24002369 Free PMC article.
BACKGROUND: Atrial fibrillation (AF) patterns and their relations with long-term prognosis are uncertain, partly because pattern definitions are challenging to implement in longitudinal data sets. ...CONCLUSIONS: In our community-based AF sample, only 10% had AF without ea …
BACKGROUND: Atrial fibrillation (AF) patterns and their relations with long-term prognosis are uncertain, partly because pattern defi …
Long-term C-reactive protein variability and prediction of metabolic risk.
Chen TH, Gona P, Sutherland PA, Benjamin EJ, Wilson PW, Larson MG, Vasan RS, Robins SJ. Chen TH, et al. Am J Med. 2009 Jan;122(1):53-61. doi: 10.1016/j.amjmed.2008.08.023. Am J Med. 2009. PMID: 19114172 Free PMC article.
An additional 24% to 51% of men and 24% to 50% of women occupied an adjacent quintile. Intermediate-term CRP variability (over 4 years) was similar to long-term variability. ...CONCLUSION: The results of this longitudinal analysis suggest the intraindividual, long- …
An additional 24% to 51% of men and 24% to 50% of women occupied an adjacent quintile. Intermediate-term CRP variability (over 4 year …