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Loss of p19Arf promotes fibroblast survival during leucine deprivation.
Roby KC, Lieberman A, Kim BJ, Rodríguez NZ, Posimo JM, Tsang T, Verginadis II, Puré E, Brady DC, Koumenis C, Ryeom S. Roby KC, et al. Among authors: pure e. Biol Open. 2022 Feb 15;11(2):bio058728. doi: 10.1242/bio.058728. Epub 2022 Feb 17. Biol Open. 2022. PMID: 34994382 Free PMC article.
Here, we show that prolonged leucine deprivation results in increased expression and nuclear localization of p19Arf, triggering apoptosis in primary murine adult lung fibroblasts (ALFs). In contrast, the absence of p19Arf during long-term leucine deprivation resulted in in …
Here, we show that prolonged leucine deprivation results in increased expression and nuclear localization of p19Arf, triggering apoptosis in …
Hematopoietic stem cell function requires 12/15-lipoxygenase-dependent fatty acid metabolism.
Kinder M, Wei C, Shelat SG, Kundu M, Zhao L, Blair IA, Puré E. Kinder M, et al. Among authors: pure e. Blood. 2010 Jun 17;115(24):5012-22. doi: 10.1182/blood-2009-09-243139. Epub 2010 Mar 31. Blood. 2010. PMID: 20357242 Free PMC article.
Furthermore, we demonstrate that 12/15-LOX is required for the maintenance of long-term HSC quiescence and number. The defect in HSCs is cell-autonomous and associated with a selective reduction in 12/15-LOX-mediated generation of bioactive lipid mediators and reactive oxy …
Furthermore, we demonstrate that 12/15-LOX is required for the maintenance of long-term HSC quiescence and number. The defect in HSCs …
Combined effects of cholesterol reduction and apolipoprotein A-I expression on atherosclerosis in LDL receptor deficient mice.
Kawashiri MA, Zhang Y, Puré E, Rader DJ. Kawashiri MA, et al. Among authors: pure e. Atherosclerosis. 2002 Nov;165(1):15-22. doi: 10.1016/s0021-9150(02)00103-x. Atherosclerosis. 2002. PMID: 12208466 Free article.
Although co-expression of the LDL receptor and apoA-I reduced atherosclerosis by 37% in the aorta and 32% in the aortic root compared with controls, the reduction in atherosclerosis was no different than that seen with expression of the LDL receptor alone or apoA-I alone. In summ …
Although co-expression of the LDL receptor and apoA-I reduced atherosclerosis by 37% in the aorta and 32% in the aortic root compared with c …
Unresponsiveness to 2,4-dinitro-1-fluoro-benzene after treatment with monoclonal antibodies to leukocyte function-associated molecule-1 and intercellular adhesion molecule-1 during sensitization.
Scheynius A, Camp RL, Puré E. Scheynius A, et al. Among authors: pure e. J Immunol. 1996 Mar 1;156(5):1804-9. J Immunol. 1996. PMID: 8596030
Together these data indicate that inhibition of LFA-1/intercellular adhesion molecule-1 mediated interactions between APCs and T cells during sensitization induced long term, Ag-specific, hyporesponsiveness of mice to the hapten 2,4-dinitro-1-fluoro-benzene....
Together these data indicate that inhibition of LFA-1/intercellular adhesion molecule-1 mediated interactions between APCs and T cells durin …
High levels of CD44 expression distinguish virgin from antigen-primed B cells.
Camp RL, Kraus TA, Birkeland ML, Puré E. Camp RL, et al. Among authors: pure e. J Exp Med. 1991 Mar 1;173(3):763-6. doi: 10.1084/jem.173.3.763. J Exp Med. 1991. PMID: 1997654 Free PMC article.
Cell sorting experiments with B cells isolated from trinitrophenyl-keyhole limpet hemocyanin-immunized mice demonstrate that both short-term antigen-specific, IgG-secreting cells and long-term antigen-primed B cells are exclusively CD44high. ...
Cell sorting experiments with B cells isolated from trinitrophenyl-keyhole limpet hemocyanin-immunized mice demonstrate that both short-t …
T cell-derived B cell differentiation factor(s). Effect on the isotype switch of murine B cells.
Isakson PC, Puré E, Vitetta ES, Krammer PH. Isakson PC, et al. Among authors: pure e. J Exp Med. 1982 Mar 1;155(3):734-48. doi: 10.1084/jem.155.3.734. J Exp Med. 1982. PMID: 7038025 Free PMC article.
The addition of supernatants from concanavalin A (Con A)-induced alloreactive (AKR anti-B6) long-term T cell lines (PK 7.1.1a and 7.1.2) or a T cell hybridoma (FS7-6.18) to LPS-treated B cells resulted in a marked increase in IgG PFC (3--10-fold higher than in cultures tre …
The addition of supernatants from concanavalin A (Con A)-induced alloreactive (AKR anti-B6) long-term T cell lines (PK 7.1.1a and 7.1 …