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Spirometry services in England post-pandemic and the potential role of AI support software: a qualitative study of challenges and opportunities.
Doe G, Taylor SJ, Topalovic M, Russell R, Evans RA, Maes J, Van Orshovon K, Sunjaya A, Scott D, Prevost AT, El-Emir E, Harvey J, Hopkinson NS, Kon SS, Patel S, Jarrold I, Spain N, Man WD, Hutchinson A. Doe G, et al. Among authors: prevost at. Br J Gen Pract. 2023 Nov 30;73(737):e915-e923. doi: 10.3399/BJGP.2022.0608. Print 2023 Dec. Br J Gen Pract. 2023. PMID: 37903639 Free PMC article.
BACKGROUND: Spirometry services to diagnose and monitor lung disease in primary care were identified as a priority in the NHS Long Term Plan, and are restarting post-COVID-19 pandemic in England; however, evidence regarding best practice is limited. ...
BACKGROUND: Spirometry services to diagnose and monitor lung disease in primary care were identified as a priority in the NHS Long Term …
Integrated Short-term Palliative Rehabilitation to improve quality of life and equitable care access in incurable cancer (INSPIRE): a multinational European research project.
Bayly J, Ahmedzai HH, Blandini MG, Bressi B, Caraceni AT, Carvalho Vasconcelos J, Costi S, Fugazzaro S, Guberti M, Guldin MB, Hauken M, Higginson I, Laird BJA, Ling J, Normand C, Nottelmann L, Oldervoll L, Payne C, Prevost AT, Stene GB, Vanzulli E, Veber E, Economos G, Maddocks M. Bayly J, et al. Among authors: prevost at. Palliat Care Soc Pract. 2023 Jun 14;17:26323524231179979. doi: 10.1177/26323524231179979. eCollection 2023. Palliat Care Soc Pract. 2023. PMID: 37377743 Free PMC article.
OBJECTIVES: To test the clinical and cost-effectiveness of an integrated short-term palliative rehabilitation intervention, to optimise function and quality of life in people affected by incurable cancer. ...
OBJECTIVES: To test the clinical and cost-effectiveness of an integrated short-term palliative rehabilitation intervention, to optimi …
Mortality of Care Home Residents and Community-Dwelling Controls During the COVID-19 Pandemic in 2020: Matched Cohort Study.
Gulliford MC, Prevost AT, Clegg A, Rezel-Potts E. Gulliford MC, et al. Among authors: prevost at. J Am Med Dir Assoc. 2022 Jun;23(6):923-929.e2. doi: 10.1016/j.jamda.2022.04.003. Epub 2022 Apr 13. J Am Med Dir Assoc. 2022. PMID: 35561757 Free PMC article.
METHODS: All-cause mortality was evaluated and adjusted rate ratios by negative binomial regression were adjusted for age, sex, number of long-term conditions, frailty category, region, calendar month or week, and clustering by family practice. ...Excess deaths for care ho …
METHODS: All-cause mortality was evaluated and adjusted rate ratios by negative binomial regression were adjusted for age, sex, number of lo …
Correction of congenital macrostomia by double reversing Z-plasty: A technical note.
Oliver C, Prévost A, Cavalier Z, Corre P, Lauwers F, Bertin H. Oliver C, et al. Among authors: prevost a. J Stomatol Oral Maxillofac Surg. 2022 Oct;123(5):527-531. doi: 10.1016/j.jormas.2022.03.016. Epub 2022 Mar 26. J Stomatol Oral Maxillofac Surg. 2022. PMID: 35346869
We here propose a technical note to refine and provide additional information for good achievement of "Double Reversing Z-Plasty" for correction of macrostomia. Our case series also reports good long-term functional and esthetic results obtained with this technique, especi …
We here propose a technical note to refine and provide additional information for good achievement of "Double Reversing Z-Plasty" for correc …
Final results of the IFCT-0803 study, a phase II study of cetuximab, pemetrexed, cisplatin, and concurrent radiotherapy in patients with locally advanced, unresectable, stage III, non-squamous, non-small-cell lung cancer.
Trédaniel J, Barlési F, Le Péchoux C, Lerouge D, Pichon É, Le Moulec S, Moreau L, Friard S, Westeel V, Petit L, Carré O, Guichard F, Raffy O, Villa J, Prévost A, Langlais A, Morin F, Wislez M, Giraud P, Zalcman G, Mornex F; French Cooperative Thoracic Intergroup (IFCT). Trédaniel J, et al. Among authors: prevost a. Cancer Radiother. 2022 Sep;26(5):670-677. doi: 10.1016/j.canrad.2021.12.005. Epub 2022 Mar 5. Cancer Radiother. 2022. PMID: 35260342 Free article. Clinical Trial.
Concurrent platinum-based chemoradiotherapy is the backbone treatment, which is followed by maintenance immunotherapy, yet with poor long-term prognosis. This phase II trial (IFCT-0803) sought to evaluate whether adding cetuximab to cisplatin and pemetrexed chemoradiothera …
Concurrent platinum-based chemoradiotherapy is the backbone treatment, which is followed by maintenance immunotherapy, yet with poor long- …
Cost Effectiveness of Ranibizumab vs Aflibercept vs Bevacizumab for the Treatment of Macular Oedema Due to Central Retinal Vein Occlusion: The LEAVO Study.
Pennington B, Alshreef A, Flight L, Metry A, Poku E, Hykin P, Sivaprasad S, Prevost AT, Vasconcelos JC, Murphy C, Kelly J, Yang Y, Lotery A, Williams M, Brazier J. Pennington B, et al. Among authors: prevost at. Pharmacoeconomics. 2021 Aug;39(8):913-927. doi: 10.1007/s40273-021-01026-5. Epub 2021 Apr 26. Pharmacoeconomics. 2021. PMID: 33900585 Free PMC article. Clinical Trial.
We performed a within-trial analysis using the efficacy, safety, resource use and health utility data from a randomised controlled trial (LEAVO) over 100 weeks. We built a discrete event simulation to model long-term outcomes. We estimated utilities using the Visual-Functi …
We performed a within-trial analysis using the efficacy, safety, resource use and health utility data from a randomised controlled trial (LE …
Who will benefit from bariatric surgery for diabetes? A protocol for an observational cohort study.
Kenkre JS, Ahmed AR, Purkayastha S, Malallah K, Bloom S, Blakemore AI, Prevost AT, Tan T. Kenkre JS, et al. Among authors: prevost at. BMJ Open. 2021 Feb 10;11(2):e042355. doi: 10.1136/bmjopen-2020-042355. BMJ Open. 2021. PMID: 33568372 Free PMC article.
The most effective treatment for obesity and T2DM is bariatric or metabolic surgery; it can lead to long-term diabetes remission with 4 in 10 of those undergoing surgery having normal blood glucose on no medication 1 year postoperatively. ...
The most effective treatment for obesity and T2DM is bariatric or metabolic surgery; it can lead to long-term diabetes remission with …
Comparative Healthcare Research Outcomes of Novel Surgery in prostate cancer (IP4-CHRONOS): A prospective, multi-centre therapeutic phase II parallel Randomised Control Trial.
Reddy D, Shah TT, Dudderidge T, McCracken S, Arya M, Dobbs C, Emberton M, Fiorentino F, Day E, Prevost AT, Staffurth J, Sydes M, Winkler M, Ahmed HU. Reddy D, et al. Among authors: prevost at. Contemp Clin Trials. 2020 Jun;93:105999. doi: 10.1016/j.cct.2020.105999. Epub 2020 Apr 14. Contemp Clin Trials. 2020. PMID: 32302790
INTRODUCTION: Focal therapy (FT) targets individual areas of cancer within the prostate, providing oncological control with minimal side-effects. Early evidence demonstrates encouraging short-medium-term outcomes. With no randomized controlled trials (RCT) comparing FT to …
INTRODUCTION: Focal therapy (FT) targets individual areas of cancer within the prostate, providing oncological control with minimal side-eff …
Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials.
Santhakumaran S, Gordon A, Prevost AT, O'Kane C, McAuley DF, Shankar-Hari M. Santhakumaran S, et al. Among authors: prevost at. Crit Care. 2019 May 3;23(1):156. doi: 10.1186/s13054-019-2446-1. Crit Care. 2019. PMID: 31053084 Free PMC article.
HTE was quantified both in additive (difference in risk difference (RD)) and multiplicative (ratio of relative risks (RR)) scales using estimated treatment differences from a logistic regression model with treatment risk as the interaction term. RESULTS: The ratio of the o …
HTE was quantified both in additive (difference in risk difference (RD)) and multiplicative (ratio of relative risks (RR)) scales using esti …
Lightmasks that prevent dark adaptation for non-central diabetic macular oedema: the CLEOPATRA RCT.
Sivaprasad S, Vasconcelos J, Holmes H, Murphy C, Kelly J, Hykin P, Prevost AT. Sivaprasad S, et al. Among authors: prevost at. Southampton (UK): NIHR Journals Library; 2019 Feb. Southampton (UK): NIHR Journals Library; 2019 Feb. PMID: 30830734 Free Books & Documents. Review.
Therefore, a lightmask emitting 500- to 505-nm light and worn at night during sleep may prevent rod-related dark adaptation and, thereby, reduce the retinal oxygen consumption and improve or prevent progression of DMO and diabetic retinopathy as evidenced in small short-term …
Therefore, a lightmask emitting 500- to 505-nm light and worn at night during sleep may prevent rod-related dark adaptation and, thereby, re …
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