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Cord-Blood-Stem-Cell-Derived Conventional Dendritic Cells Specifically Originate from CD115-Expressing Precursors.
Plantinga M, de Haar CG, Dünnebach E, van den Beemt DAMH, Bloemenkamp KWM, Mokry M, Boelens JJ, Nierkens S. Plantinga M, et al. Cancers (Basel). 2019 Feb 5;11(2):181. doi: 10.3390/cancers11020181. Cancers (Basel). 2019. PMID: 30764500 Free PMC article.
The discovery of a committed DC precursor in CB-derived stem cell cultures further enables utilization of conventional DC-based vaccines to provide powerful antitumor activity and long-term memory immunity....
The discovery of a committed DC precursor in CB-derived stem cell cultures further enables utilization of conventional DC-based vaccines to …
Generation of a cord blood-derived Wilms Tumor 1 dendritic cell vaccine for AML patients treated with allogeneic cord blood transplantation.
de Haar C, Plantinga M, Blokland NJ, van Til NP, Flinsenberg TW, Van Tendeloo VF, Smits EL, Boon L, Spel L, Boes M, Boelens JJ, Nierkens S. de Haar C, et al. Among authors: plantinga m. Oncoimmunology. 2015 May 27;4(11):e1023973. doi: 10.1080/2162402X.2015.1023973. eCollection 2015 Nov. Oncoimmunology. 2015. PMID: 26451309 Free PMC article.
As the elicitation of tumor-antigen specific cytotoxic T lymphocytes (CTLs) is associated with reduced relapses and enhanced survival, enhanced priming of these CTLs using an anti-AML vaccine may result in long-term immunity against AML. Cord blood (CB), as allogeneic HCT …
As the elicitation of tumor-antigen specific cytotoxic T lymphocytes (CTLs) is associated with reduced relapses and enhanced survival, enhan …