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Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes.
Suzuki T, Asami M, Hoffmann M, Lu X, Gužvić M, Klein CA, Perry ACF. Suzuki T, et al. Among authors: perry acf. Nat Commun. 2016 Sep 13;7:12676. doi: 10.1038/ncomms12676. Nat Commun. 2016. PMID: 27623537 Free PMC article.
We here challenge this view and demonstrate that mouse embryos in the mitotic cell cycle can also directly reprogram sperm for full-term development. Developmentally incompetent haploid embryos (parthenogenotes) injected with sperm developed to produce healthy offspring at …
We here challenge this view and demonstrate that mouse embryos in the mitotic cell cycle can also directly reprogram sperm for full-term
National Athletic Trainers' Association position statement: safe weight loss and maintenance practices in sport and exercise.
Turocy PS, DePalma BF, Horswill CA, Laquale KM, Martin TJ, Perry AC, Somova MJ, Utter AC; National Athletic Trainers’ Association. Turocy PS, et al. Among authors: perry ac. J Athl Train. 2011 May-Jun;46(3):322-36. doi: 10.4085/1062-6050-46.3.322. J Athl Train. 2011. PMID: 21669104 Free PMC article.
In some cases, a registered nutritionist may have equivalent credentials and be the commonly used term. All weight management and exercise protocols used to achieve these goals should be safe and based on the most current evidence. ...
In some cases, a registered nutritionist may have equivalent credentials and be the commonly used term. All weight management and exe …
Full-term mouse development by abolishing Zn2+-dependent metaphase II arrest without Ca2+ release.
Suzuki T, Yoshida N, Suzuki E, Okuda E, Perry AC. Suzuki T, et al. Among authors: perry ac. Development. 2010 Aug;137(16):2659-69. doi: 10.1242/dev.049791. Epub 2010 Jun 30. Development. 2010. PMID: 20591924 Free article.
Here, we delineate the role of Ca(2+) release during mII exit in wild-type mouse eggs and show that it is dispensable for full-term development. Exit from mII can be induced by Zn(2+)-specific sequestration without Ca(2+) release, eliciting Cyclin B degradation in a manner …
Here, we delineate the role of Ca(2+) release during mII exit in wild-type mouse eggs and show that it is dispensable for full-term d …
Effects of sibutramine treatment in obese adolescents: a randomized trial.
Berkowitz RI, Fujioka K, Daniels SR, Hoppin AG, Owen S, Perry AC, Sothern MS, Renz CL, Pirner MA, Walch JK, Jasinsky O, Hewkin AC, Blakesley VA; Sibutramine Adolescent Study Group. Berkowitz RI, et al. Among authors: perry ac. Ann Intern Med. 2006 Jul 18;145(2):81-90. doi: 10.7326/0003-4819-145-2-200607180-00005. Ann Intern Med. 2006. PMID: 16847290 Clinical Trial.
LIMITATIONS: The 1-year study duration precluded assessment of long-term weight maintenance and putative health benefits and harms, and 24% and 38% of the sibutramine and placebo groups, respectively, did not complete follow-up. ...
LIMITATIONS: The 1-year study duration precluded assessment of long-term weight maintenance and putative health benefits and harms, a …
Mammalian Emi2 mediates cytostatic arrest and transduces the signal for meiotic exit via Cdc20.
Shoji S, Yoshida N, Amanai M, Ohgishi M, Fukui T, Fujimoto S, Nakano Y, Kajikawa E, Perry AC. Shoji S, et al. Among authors: perry ac. EMBO J. 2006 Feb 22;25(4):834-45. doi: 10.1038/sj.emboj.7600953. Epub 2006 Feb 2. EMBO J. 2006. PMID: 16456547 Free PMC article.
We here present evidence that a conserved 71 kDa mammalian orthologue of Xenopus XErp1/Emi2, which we term endogenous meiotic inhibitor 2 (Emi2) is an essential CSF component. ...
We here present evidence that a conserved 71 kDa mammalian orthologue of Xenopus XErp1/Emi2, which we term endogenous meiotic inhibit …
Physical and psychological changes with vigorous exercise in sedentary primigravidae.
Marquez-Sterling S, Perry AC, Kaplan TA, Halberstein RA, Signorile JF. Marquez-Sterling S, et al. Among authors: perry ac. Med Sci Sports Exerc. 2000 Jan;32(1):58-62. doi: 10.1097/00005768-200001000-00010. Med Sci Sports Exerc. 2000. PMID: 10647530 Clinical Trial.
There were no significant differences between E and C groups in any pregnancy outcome measures. All babies were delivered healthy at term. CONCLUSIONS: These data suggest that a vigorous exercise program can lead to significant improvements in aerobic fitness at similar la …
There were no significant differences between E and C groups in any pregnancy outcome measures. All babies were delivered healthy at term
Mice cloned from embryonic stem cells.
Wakayama T, Rodriguez I, Perry AC, Yanagimachi R, Mombaerts P. Wakayama T, et al. Among authors: perry ac. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14984-9. doi: 10.1073/pnas.96.26.14984. Proc Natl Acad Sci U S A. 1999. PMID: 10611324 Free PMC article.
Nuclei from the ES cell line E14 also were shown to direct development to term. We present evidence that the nuclei of ES cells at G(1)- or G(2)/M-phases are efficiently able to support full development. ...
Nuclei from the ES cell line E14 also were shown to direct development to term. We present evidence that the nuclei of ES cells at G( …
Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei.
Wakayama T, Perry AC, Zuccotti M, Johnson KR, Yanagimachi R. Wakayama T, et al. Among authors: perry ac. Nature. 1998 Jul 23;394(6691):369-74. doi: 10.1038/28615. Nature. 1998. PMID: 9690471
Once transferred, many of these embryos implanted and, although most were subsequently resorbed, a significant proportion (2 to 2.8%) developed to term. These experiments show that for mammals, nuclei from terminally differentiated, adult somatic cells of known phenotype i …
Once transferred, many of these embryos implanted and, although most were subsequently resorbed, a significant proportion (2 to 2.8%) develo …
Effects of acute inhalation of the bronchodilator, albuterol, on power output.
Signorile JF, Kaplan TA, Applegate B, Perry AC. Signorile JF, et al. Among authors: perry ac. Med Sci Sports Exerc. 1992 Jun;24(6):638-42. Med Sci Sports Exerc. 1992. PMID: 1318486 Clinical Trial.
These results indicate an ergogenic effect of the bronchodilator on short-term power output independent of impact on respiratory smooth muscle, with no effect on cardiac response....
These results indicate an ergogenic effect of the bronchodilator on short-term power output independent of impact on respiratory smoo …