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Circulating adrenomedullin estimates survival and reversibility of organ failure in sepsis: the prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock-1 (AdrenOSS-1) study.
Mebazaa A, Geven C, Hollinger A, Wittebole X, Chousterman BG, Blet A, Gayat E, Hartmann O, Scigalla P, Struck J, Bergmann A, Antonelli M, Beishuizen A, Constantin JM, Damoisel C, Deye N, Di Somma S, Dugernier T, François B, Gaudry S, Huberlant V, Lascarrou JB, Marx G, Mercier E, Oueslati H, Pickkers P, Sonneville R, Legrand M, Laterre PF; AdrenOSS-1 study investigators. Mebazaa A, et al. Crit Care. 2018 Dec 21;22(1):354. doi: 10.1186/s13054-018-2243-2. Crit Care. 2018. PMID: 30583748 Free PMC article.
In the present prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock 1 (, AdrenOSS-1) study, we assessed relationships between circulating bio-ADM during the initial intensive care unit (ICU) stay and short-term outcome in order to e …
In the present prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock 1 (, AdrenOSS-1) study, we asse …
Sevoflurane for procedural sedation in critically ill patients: A pharmacokinetic comparative study between burn and non-burn patients.
Perbet S, Bourdeaux D, Lenoire A, Biboulet C, Pereira B, Sadoune M, Plaud B, Launay JM, Bazin JE, Sautou V, Mebazaa A, Houze P, Constantin JM, Legrand M; PRONOBURN group. Perbet S, et al. Anaesth Crit Care Pain Med. 2018 Dec;37(6):551-556. doi: 10.1016/j.accpm.2018.02.001. Epub 2018 Feb 15. Anaesth Crit Care Pain Med. 2018. PMID: 29455032
The sevoflurane was administered with an expired fraction target of 2% during short-term procedural sedation. Plasma concentrations of sevoflurane, hexafluoroisopropanolol (HFIP) and free fluoride ions were recorded at different times. ...
The sevoflurane was administered with an expired fraction target of 2% during short-term procedural sedation. Plasma concentrations o …
A pharmacokinetic study of 48-hour sevoflurane inhalation using a disposable delivery system (AnaConDa®) in ICU patients.
Perbet S, Bourdeaux D, Sautou V, Pereira B, Chabanne R, Constantin JM, Chopineau J, Bazin JE. Perbet S, et al. Minerva Anestesiol. 2014 Jun;80(6):655-65. Epub 2013 Nov 13. Minerva Anestesiol. 2014. PMID: 24226486 Free article.
BACKGROUND: Little is known regarding sevoflurane kinetics and toxicity during long-term sedation of intensive care unit (ICU) patients using the AnaConDa system. ...
BACKGROUND: Little is known regarding sevoflurane kinetics and toxicity during long-term sedation of intensive care unit (ICU) patien …
Influence of opioid choice on mechanical ventilation duration and ICU length of stay.
Futier E, Chanques G, Cayot Constantin S, Vernis L, Barres A, Guerin R, Chartier C, Perbet S, Petit A, Jabaudon M, Bazin JE, Constantin JM. Futier E, et al. Among authors: perbet s. Minerva Anestesiol. 2012 Jan;78(1):46-53. Epub 2011 Nov 5. Minerva Anestesiol. 2012. PMID: 21971434 Free article.
CONCLUSION: Our study suggests that using a short-acting opiate with short context-sensitive half-life in an analgesia-based sedation protocol may significantly decrease the duration of mechanical ventilation and the ICU length of stay even though not significantly in long ter …
CONCLUSION: Our study suggests that using a short-acting opiate with short context-sensitive half-life in an analgesia-based sedation protoc …
Infectious complications in out-of-hospital cardiac arrest patients in the therapeutic hypothermia era.
Mongardon N, Perbet S, Lemiale V, Dumas F, Poupet H, Charpentier J, Péne F, Chiche JD, Mira JP, Cariou A. Mongardon N, et al. Among authors: perbet s. Crit Care Med. 2011 Jun;39(6):1359-64. doi: 10.1097/CCM.0b013e3182120b56. Crit Care Med. 2011. PMID: 21336107
We investigated the infectious complications in cardiac arrest survivors and assessed their impact on morbidity and long-term outcome. DESIGN: Retrospective review of a prospectively acquired intensive care unit database. ...CONCLUSIONS: Infectious complications are freque …
We investigated the infectious complications in cardiac arrest survivors and assessed their impact on morbidity and long-term outcome …
A recruitment maneuver increases oxygenation after intubation of hypoxemic intensive care unit patients: a randomized controlled study.
Constantin JM, Futier E, Cherprenet AL, Chanques G, Guerin R, Cayot-Constantin S, Jabaudon M, Perbet S, Chartier C, Jung B, Guelon D, Jaber S, Bazin JE. Constantin JM, et al. Among authors: perbet s. Crit Care. 2010;14(2):R76. doi: 10.1186/cc8989. Epub 2010 Apr 28. Crit Care. 2010. PMID: 20426859 Free PMC article. Clinical Trial.
CONCLUSIONS: Recruitment maneuver following intubation in hypoxemic patients improved short-term oxygenation, and was not associated with increased adverse effects. ...
CONCLUSIONS: Recruitment maneuver following intubation in hypoxemic patients improved short-term oxygenation, and was not associated …
Femoral vs jugular venous catheterization and risk of nosocomial events in adults requiring acute renal replacement therapy: a randomized controlled trial.
Parienti JJ, Thirion M, Mégarbane B, Souweine B, Ouchikhe A, Polito A, Forel JM, Marqué S, Misset B, Airapetian N, Daurel C, Mira JP, Ramakers M, du Cheyron D, Le Coutour X, Daubin C, Charbonneau P; Members of the Cathedia Study Group. Parienti JJ, et al. JAMA. 2008 May 28;299(20):2413-22. doi: 10.1001/jama.299.20.2413. JAMA. 2008. PMID: 18505951 Clinical Trial.
CONTEXT: Based on concerns about the risk of infection, the jugular site is often preferred over the femoral site for short-term dialysis vascular access. OBJECTIVE: To determine whether jugular catheterization decreases the risk of nosocomial complications compared with f …
CONTEXT: Based on concerns about the risk of infection, the jugular site is often preferred over the femoral site for short-term dial …