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The gut microbiota in adults with cystic fibrosis compared to colorectal cancer.
Caley LR, Wood HM, Bottomley D, Fuentes Balaguer A, Wilkinson L, Dyson J, Young C, White H, Benton S, Brearley M, Quirke P, Peckham DG. Caley LR, et al. Among authors: peckham dg. J Cyst Fibros. 2023 Dec 15:S1569-1993(23)01728-9. doi: 10.1016/j.jcf.2023.12.004. Online ahead of print. J Cyst Fibros. 2023. PMID: 38104000 Free article.
Studies assessing the impact of dietary or other interventions and the longer-term use of CFTR modulators on reducing this potentially pro-oncogenic milieu are needed....
Studies assessing the impact of dietary or other interventions and the longer-term use of CFTR modulators on reducing this potentiall …
Long-term safety and efficacy of tezacaftor-ivacaftor in individuals with cystic fibrosis aged 12 years or older who are homozygous or heterozygous for Phe508del CFTR (EXTEND): an open-label extension study.
Flume PA, Biner RF, Downey DG, Brown C, Jain M, Fischer R, De Boeck K, Sawicki GS, Chang P, Paz-Diaz H, Rubin JL, Yang Y, Hu X, Pasta DJ, Millar SJ, Campbell D, Wang X, Ahluwalia N, Owen CA, Wainwright CE; VX14-661-110 study group. Flume PA, et al. Lancet Respir Med. 2021 Jul;9(7):733-746. doi: 10.1016/S2213-2600(20)30510-5. Epub 2021 Feb 10. Lancet Respir Med. 2021. PMID: 33581080
Here, we present results of study 661-110 (EXTEND), a 96-week open-label extension study that assessed long-term safety, tolerability, and efficacy of tezacaftor-ivacaftor in participants aged 12 years or older with cystic fibrosis who were homozygous or heterozygous for t …
Here, we present results of study 661-110 (EXTEND), a 96-week open-label extension study that assessed long-term safety, tolerability …
Enteral tube feeding in adults with cystic fibrosis; patient choice and impact on long term outcomes.
White H, Morton AM, Conway SP, Peckham DG. White H, et al. Among authors: peckham dg. J Cyst Fibros. 2013 Dec;12(6):616-22. doi: 10.1016/j.jcf.2013.05.003. Epub 2013 Jun 14. J Cyst Fibros. 2013. PMID: 23770301 Free article.
BACKGROUND: Enteral tube feeding (ETF) has been evaluated in paediatric and mixed child and adult populations with cystic fibrosis, demonstrating positive outcomes from 6 months to 2 years post insertion. No studies have examined the longer term nutritional and clinical ou …
BACKGROUND: Enteral tube feeding (ETF) has been evaluated in paediatric and mixed child and adult populations with cystic fibrosis, demonstr …
Ten years of viral and non-bacterial serology in adults with cystic fibrosis.
Clifton IJ, Kastelik JA, Peckham DG, Hale A, Denton M, Etherington C, Conway SP. Clifton IJ, et al. Among authors: peckham dg. Epidemiol Infect. 2008 Jan;136(1):128-34. doi: 10.1017/S0950268807008278. Epub 2007 Mar 12. Epidemiol Infect. 2008. PMID: 17352838 Free PMC article.
The presence of viral infection in association with a pulmonary exacerbation did not adversely affect lung function or inflammatory markers in the short term. Adults with CF have a lower incidence of respiratory viral infections associated with pulmonary exacerbations requ …
The presence of viral infection in association with a pulmonary exacerbation did not adversely affect lung function or inflammatory markers …
Improvement in patient compliance with long-term oxygen therapy following formal assessment with training.
Peckham DG, McGibbon K, Tonkinson J, Plimbley G, Pantin C. Peckham DG, et al. Respir Med. 1998 Oct;92(10):1203-6. doi: 10.1016/s0954-6111(98)90422-x. Respir Med. 1998. PMID: 9926150 Free article.
In the Department of Respiratory Medicine, North Staffordshire Hospital, patients fulfilling the Department of Health criteria for long-term oxygen therapy (LTOT) attend a practical teaching session on the use of their oxygen concentrator before commencing therapy. ...
In the Department of Respiratory Medicine, North Staffordshire Hospital, patients fulfilling the Department of Health criteria for long-t …