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A Proinflammatory Stimulus Disrupts Hippocampal Plasticity and Learning via Microglial Activation and 25-Hydroxycholesterol.
Izumi Y, Cashikar AG, Krishnan K, Paul SM, Covey DF, Mennerick SJ, Zorumski CF. Izumi Y, et al. Among authors: paul sm. J Neurosci. 2021 Dec 8;41(49):10054-10064. doi: 10.1523/JNEUROSCI.1502-21.2021. Epub 2021 Nov 1. J Neurosci. 2021. PMID: 34725187 Free PMC article.
Wild-type microglia produced higher levels of 25HC than Ch25h knock-out (KO) microglia with or without LPS. LPS treatment also disrupts long-term potentiation (LTP) in hippocampal slices via induction of a form of NMDA receptor-dependent metaplasticity. ...
Wild-type microglia produced higher levels of 25HC than Ch25h knock-out (KO) microglia with or without LPS. LPS treatment also disrupts long …
Distinct attentional function profiles in older adults receiving cancer chemotherapy.
Utne I, Løyland B, Grov EK, Rasmussen HL, Torstveit AH, Cooper BA, Mastick J, Mazor M, Wong M, Paul SM, Conley YP, Jahan T, Ritchie C, Levine JD, Miaskowski C. Utne I, et al. Among authors: paul sm. Eur J Oncol Nurs. 2018 Oct;36:32-39. doi: 10.1016/j.ejon.2018.08.006. Epub 2018 Aug 22. Eur J Oncol Nurs. 2018. PMID: 30322507 Free PMC article.
Scoliosis in Fibrous Dysplasia/McCune-Albright Syndrome: Factors Associated With Curve Progression and Effects of Bisphosphonates.
Berglund JA, Tella SH, Tuthill KF, Kim L, Guthrie LC, Paul SM, Stanton R, Collins MT, Boyce AM. Berglund JA, et al. Among authors: paul sm. J Bone Miner Res. 2018 Sep;33(9):1641-1648. doi: 10.1002/jbmr.3446. Epub 2018 May 22. J Bone Miner Res. 2018. PMID: 29669167 Free article. Clinical Trial.
Scoliosis is a complication of fibrous dysplasia/McCune-Albright syndrome (FD/MAS); however, risk factors and long-term outcomes are unknown. Bisphosphonates are commonly used; however, it is unknown whether their use decrease the risk of progressive scoliosis. ...Current …
Scoliosis is a complication of fibrous dysplasia/McCune-Albright syndrome (FD/MAS); however, risk factors and long-term outcomes are …
Preoperative Pain, Symptoms, and Psychological Factors related to Higher Acute Pain Trajectories during Hospitalization for Total Knee Arthroplasty.
Lindberg MF, Miaskowski C, Rustøen T, Rosseland LA, Paul SM, Lerdal A. Lindberg MF, et al. Among authors: paul sm. PLoS One. 2016 Sep 1;11(9):e0161681. doi: 10.1371/journal.pone.0161681. eCollection 2016. PLoS One. 2016. PMID: 27583551 Free PMC article.
Future research needs to test the efficacy of interventions that modify patients' perceptions of living with OA and pain intensity before surgery on short and long term postoperative outcomes....
Future research needs to test the efficacy of interventions that modify patients' perceptions of living with OA and pain intensity before su …
Cancer Among Children With Perinatal Exposure to HIV and Antiretroviral Medications--New Jersey, 1995-2010.
Ivy W 3rd, Nesheim SR, Paul SM, Ibrahim AR, Chan M, Niu X, Lampe MA. Ivy W 3rd, et al. Among authors: paul sm. J Acquir Immune Defic Syndr. 2015 Sep 1;70(1):62-6. doi: 10.1097/QAI.0000000000000695. J Acquir Immune Defic Syndr. 2015. PMID: 26017660 Free PMC article.
BACKGROUND: Concerns remain regarding the cancer risk associated with perinatal antiretroviral (ARV) exposure among infants. No excessive cancer risk has been found in short-term studies. METHODS: Children born to HIV-infected women (HIV-exposed) in New Jersey from 1995 to …
BACKGROUND: Concerns remain regarding the cancer risk associated with perinatal antiretroviral (ARV) exposure among infants. No excessive ca …
Persistent arm pain is distinct from persistent breast pain following breast cancer surgery.
Langford DJ, Paul SM, West C, Abrams G, Elboim C, Levine JD, Hamolsky D, Luce JA, Kober KM, Neuhaus JM, Cooper BA, Aouizerat BE, Miaskowski C. Langford DJ, et al. Among authors: paul sm. J Pain. 2014 Dec;15(12):1238-47. doi: 10.1016/j.jpain.2014.08.013. J Pain. 2014. PMID: 25439319 Free PMC article.
Persistent arm pain was associated with sustained interference with daily functioning and upper body mobility impairments. Long-term management of persistent pain following breast cancer surgery is warranted to improve the quality of survivorship for these women....
Persistent arm pain was associated with sustained interference with daily functioning and upper body mobility impairments. Long-term …
Persistent breast pain following breast cancer surgery is associated with persistent sensory changes, pain interference, and functional impairments.
Langford DJ, Paul SM, West C, Levine JD, Hamolsky D, Elboim C, Schmidt BL, Cooper BA, Abrams G, Aouizerat BE, Miaskowski C. Langford DJ, et al. Among authors: paul sm. J Pain. 2014 Dec;15(12):1227-37. doi: 10.1016/j.jpain.2014.08.014. J Pain. 2014. PMID: 25439318 Free PMC article.
Pervasive sensory loss and the association between persistent breast pain and sustained interference with function suggest the need for long-term clinical follow-up....
Pervasive sensory loss and the association between persistent breast pain and sustained interference with function suggest the need for long …
Bisphosphonate treatment for children with disabling conditions.
Boyce AM, Tosi LL, Paul SM. Boyce AM, et al. Among authors: paul sm. PM R. 2014 May;6(5):427-36. doi: 10.1016/j.pmrj.2013.10.009. Epub 2013 Dec 22. PM R. 2014. PMID: 24368091 Free PMC article. Review.
Although bisphosphonates are commonly prescribed for treatment of adult osteoporosis, their use in pediatric patients is controversial because of the lack of long-term safety and efficacy data....
Although bisphosphonates are commonly prescribed for treatment of adult osteoporosis, their use in pediatric patients is controversial becau …
The major brain cholesterol metabolite 24(S)-hydroxycholesterol is a potent allosteric modulator of N-methyl-D-aspartate receptors.
Paul SM, Doherty JJ, Robichaud AJ, Belfort GM, Chow BY, Hammond RS, Crawford DC, Linsenbardt AJ, Shu HJ, Izumi Y, Mennerick SJ, Zorumski CF. Paul SM, et al. J Neurosci. 2013 Oct 30;33(44):17290-300. doi: 10.1523/JNEUROSCI.2619-13.2013. J Neurosci. 2013. PMID: 24174662 Free PMC article.
In hippocampal slices, 24(S)-HC enhances the ability of subthreshold stimuli to induce long-term potentiation (LTP). 24(S)-HC also reverses hippocampal LTP deficits induced by the NMDAR channel blocker ketamine. ...
In hippocampal slices, 24(S)-HC enhances the ability of subthreshold stimuli to induce long-term potentiation (LTP). 24(S)-HC also re …
Sustained response and prevention of damage progression in patients with neonatal-onset multisystem inflammatory disease treated with anakinra: a cohort study to determine three- and five-year outcomes.
Sibley CH, Plass N, Snow J, Wiggs EA, Brewer CC, King KA, Zalewski C, Kim HJ, Bishop R, Hill S, Paul SM, Kicker P, Phillips Z, Dolan JG, Widemann B, Jayaprakash N, Pucino F, Stone DL, Chapelle D, Snyder C, Butman JA, Wesley R, Goldbach-Mansky R. Sibley CH, et al. Among authors: paul sm. Arthritis Rheum. 2012 Jul;64(7):2375-86. doi: 10.1002/art.34409. Arthritis Rheum. 2012. PMID: 22294344 Free PMC article. Clinical Trial.
OBJECTIVE: Blocking interleukin-1 with anakinra in patients with the autoinflammatory syndrome neonatal-onset multisystem inflammatory disease (NOMID) reduces systemic and organ-specific inflammation. However, the impact of long-term treatment has not been established. Thi …
OBJECTIVE: Blocking interleukin-1 with anakinra in patients with the autoinflammatory syndrome neonatal-onset multisystem inflammatory disea …
27 results